Glaucoma: An Open Window to Neurodegeneration and Neuroprotection

Content: 
Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection
Page iii

Copyright page
Page iv

List of Contributors
Pages v-ix

Preface
Page xi

Epidemiology of primary glaucoma: prevalence, incidence, and blinding effects Review Article
Pages 3-14
Claudio Cedrone, Raffaele Mancino, Angelica Cerulli, Massimo Cesareo, Carlo Nucci

Predictive models to estimate the risk of glaucoma development and progression Review Article
Pages 15-24
Felipe A. Medeiros, Robert N. Weinreb

Intraocular pressure and central corneal thickness Review Article
Pages 25-30
Gianluca Manni, Francesco Oddone, Vincenzo Parisi, Adriana Tosto, Marco Centofanti

Angle-closure: risk factors, diagnosis and treatment Review Article
Pages 31-45
Nishani Amerasinghe, Tin Aung

Early diagnosis in glaucoma Review Article
Pages 47-57
David F. Garway-Heath

Monitoring glaucoma progression Review Article
Pages 59-73
Paolo Brusini

Standard automated perimetry and algorithms for monitoring glaucoma progression Review Article
Pages 77-99
G.L. Scuderi, M. Cesareo, A. Perdicchi, S.M. Recupero

Short-wavelength automated perimetry and frequency-doubling technology perimetry in glaucoma Review Article
Pages 101-124
Paolo Fogagnolo, Luca Rossetti, Stefano Ranno, Antonio Ferreras, Nicola Orzalesi

Scanning laser polarimetry and confocal scanning laser ophthalmoscopy: technical notes on their use in glaucoma Review Article
Pages 125-138
Felicia Ferreri, Pasquale Aragona, Giuseppe Ferreri

The role of OCT in glaucoma management Review Article
Pages 139-148
Monica M. Pagliara, Domenico Lepore, Emilio Balestrazzi

Functional laser Doppler flowmetry of the optic nerve: physiological aspects and clinical applications Review Article
Pages 149-163
Charles E. Riva, Benedetto Falsini

Advances in neuroimaging of the visual pathways and their use in glaucoma Review Article
Pages 165-177
Francesco Giuseppe Garaci, Valeria Cozzolino, Carlo Nucci, Fabrizio Gaudiello, Andrea Ludovici, Tommaso Lupattelli, Roberto Floris, Giovanni Simonetti

Primary open angle glaucoma: an overview on medical therapy Review Article
Pages 181-193
Michele Vetrugno, Francesco Cantatore, Giuseppe Ruggeri, Paolo Ferreri, Alfonso Montepara, Alessandra Quinto, Carlo Sborgia

The treatment of normal-tension glaucoma Review Article
Pages 195-210
Priya V. Desai, Joseph Caprioli

The management of exfoliative glaucoma Review Article
Pages 211-224
Robert Ritch

Laser therapies for glaucoma: new frontiers Review Article
Pages 225-236
G.L. Scuderi, N. Pasquale

Modulation of wound healing during and after glaucoma surgery Review Article
Pages 237-254
Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, Peng Tee Khaw

Surgical alternative to trabeculectomy Review Article
Pages 255-261
Roberto G. Carassa

Modern aqueous shunt implantation: future challenges Review Article
Pages 263-276
Keith Barton, Dale K. Heuer

Model systems for experimental studies: retinal ganglion cells in culture Review Article
Pages 279-284
Emilie Goodyear, Leonard A. Levin

Rat models for glaucoma research Review Article
Pages 285-301
John C. Morrison, Elaine Johnson, William O. Cepurna

Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection Review Article
Pages 303-321
Gareth R. Howell, Richard T. Libby, Simon W.M. John

Clinical trials in neuroprotection Review Article
Pages 323-335
Scott M. Whitcup

Pathogenesis of ganglion “cell death” in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria Review Article
Pages 339-352
Neville N. Osborne

Astrocytes in glaucomatous optic neuropathy Review Article
Pages 353-373
M. Rosario Hernandez, Haixi Miao, Thomas Lukas

Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation Review Article
Pages 375-384
Michal Schwartz, Anat London

Oxidative stress and glaucoma: injury in the anterior segment of the eye Review Article
Pages 385-407
S.C. Sacc`, A. Izzotti

TNF-α signaling in glaucomatous neurodegeneration Review Article
Pages 409-421
Gülgün Tezel

Involvement of the Bcl2 gene family in the signaling and control of retinal ganglion cell death Review Article
Pages 423-435
Robert W. Nickells, Sheila J. Semaan, Cassandra L. Schlamp

Assessment of neuroprotection in the retina with DARC Review Article
Pages 437-450
Li Guo, M. Francesca Cordeiro

Potential roles of (endo)cannabinoids in the treatment of glaucoma: from intraocular pressure control to neuroprotection Review Article
Pages 451-464
Carlo Nucci, Monica Bari, Arnoldo Spanò, MariaTiziana Corasaniti, Giacinto Bagetta, Mauro Maccarrone, Luigi Antonio Morrone

Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration Review Article
Pages 465-478
Yeni Yücel, Neeru Gupta

Changes of central visual receptive fields in experimental glaucoma Review Article
Pages 479-491
S.C. Sharma

Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma Review Article
Pages 495-510
Masaaki Seki, Stuart A. Lipton

Stem cells for neuroprotection in glaucoma Review Article
Pages 511-519
N.D. Bull, T.V. Johnson, K.R. Martin

The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells Review Article
Pages 521-540
N.G.F. Cooper, A. Laabich, W. Fan, X. Wang

Evidence of the neuroprotective role of citicoline in glaucoma patients Review Article
Pages 541-554
Vincenzo Parisi, Giovanni Coppola, Marco Centofanti, Francesco Oddone, Anna Maria Angrisani, Lucia Ziccardi, Benedetto Ricci, Luciano Quaranta, Gianluca Manni

Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon Review Article
Pages 555-573
S. Pucci, P. Mazzarelli, F. Missiroli, F. Regine, F. Ricci

Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection Review Article
Pages 575-582
Rossella Russo, Federica Cavaliere, Laura Rombol`, Micaela Gliozzi, Angelica Cerulli, Carlo Nucci, Elisa Fazzi, Giacinto Bagetta, Maria Tiziana Corasaniti, Luigi Antonio Morrone

17β-Estradiol prevents retinal ganglion cell loss induced by acute rise of intraocular pressure in rat Review Article
Pages 583-590
Rossella Russo, Federica Cavaliere, Chizuko Watanabe, Carlo Nucci, Giacinto Bagetta, Maria Tiziana Corasaniti, Shinobu Sakurada, Luigi Antonio Morrone

Subject Index
Pages 591-622