Germ-Free Biology Experimental and Clinical Aspects: Proceedings of an International Symposium on Gnotobiology held in Buffalo, New York, June 9–11, 1968

Front Matter....Pages i-xii
The Application of Laminar Flow Rooms to Patient Isolation....Pages 1-10
Technical Advances in Patient Isolation....Pages 11-18
Laminar Air Flow Unit for Patients Undergoing Cancer Chemotherapy....Pages 19-26
Psychologic Adaptation of Patients During Treatment of Acute Leukemia in Life Island Isolator....Pages 27-34
Fever and Infection in Patients Treated with Intensive Antineoplastic Chemotherapy in an Isolator....Pages 35-43
Gnotobiotic Man....Pages 45-61
Penicillin Prophylaxis of Post-Operative Clostridial Gangrene in Monocontaminated Guinea Pigs....Pages 63-64
Intestinal Monocontamination in the Neonatal Pig: Microbiological and Microscopic Studies....Pages 65-73
The Peribronchial Lymphocytic Tissue in Germfree, Defined-Flora, Conventional and Chronic Murine Pneumonia-Affected Rats....Pages 75-84
Bacterial Burden and Wound Repair in Conventional and Germfree Rats....Pages 85-95
Effect of Type of Diet on Cholesterol Absorption and Bile Salt Excretion in Germfree and Conventional Chicks....Pages 97-105
Infectivity of Avian Reoviruses for Day-Old Chicks Under Germ-free and Isolation Conditions....Pages 107-109
Erythropoietic Response of Germfree Mice to Erythropoietin....Pages 111-116
Viral Status of Germfree Rodents; Present and Future....Pages 117-124
Leukemia in Germfree AKR Mice....Pages 125-134
Reticular Neoplasms in Irradiated and Unirradiated Germfree Mice....Pages 135-141
Comparison Between the Effects of a Single Dose of a Chemical Carcinogen on Gnotobiotic and Conventional Mice....Pages 143-148
Rous Sarcoma Virus in Germfree Rats....Pages 149-152
7, 12-Dimethylbenz(α) Anthracene-Induced Malignant Lymphoma in Germfree Mice....Pages 153-161
Gnotobiotes as Useful Tools in Studies in Carcinogenesis with Cycasin, a Natural Glucoside....Pages 163-167
Bidirectional Permeation of Water and Amino Acids in the Cecum of Germfree Rats....Pages 169-170
Recent Progress in Studies on a Bioactive Pigment (“Alpha Pigment”) Isolated from Cecal Contents of Germfree Rodents....Pages 171-172
Kinin-Forming Activity in Cecal Contents of Germ-Free and Conventional Mice....Pages 173-177
Effects of Clostridium Difficile, Lactobacillus Casei, Bacillus Subtilis and Lactobacillus sp. as Mono- and Dicontaminants on the Cecum of Germfree Mice....Pages 179-180
Similarities Between Germfree Mice and Mice with an Antibiotic Decontaminated Digestive Tract....Pages 181-189
The Effect of Intestinal Flora on Toxicity of Nitrogen Mustard....Pages 191-196
Effects of the Normal Flora on Host Defenses Against Microbial Invasion....Pages 197-206
Ageing and Resistance to Infection in Germfree C3Hf Mice....Pages 207-217
Studies of the Effects of Immune Serum on the Course of E. Coli Infections in Gnotobiotic Pigs....Pages 219-225
Differentiation of Potentially Immunocompetent Cells in the Mouse....Pages 227-235
A Comparative Study of the Immune Reaction in Germfree and Conventional Mice....Pages 237-248
Development of Immunologic Competence in Germfree and Conventional Mice....Pages 249-258
The True Primary Immune Response in Germfree Colostrum-Deprived Piglets....Pages 259-267
Hemolytic Plaque-Forming Cells and Antigen-Sensitive Units in Spleens of Germfree and Conventional Mice....Pages 269-275
Severity of the Parent to F 1 Graft-Versus-Host Reaction in Irradiated Germfree Mice....Pages 277-286
Diet and Immune Mechanisms....Pages 287-292
The Response of Germfree Rats to Dietary Cholesterol....Pages 293-295
The Absorption of Fat by Germfree and Conventionalized Rats....Pages 297-300
Protein Metabolism in Germfree Rats Fed Chemically Defined, Water-Soluble Diet and Semisynthetic Diet....Pages 301-305
Sudden Death in Germfree Mice Reared Through Successive Generations on Chemically Defined Liquid Diet....Pages 307-315
The Nephropathy of Acute Choline Deficiency in Germfree, Conventionalized and Open Animal Room Rats....Pages 317-323
Comparison of the 1- 14 C-Glucose Metabolism between Red Blood Cells of Germfree and Pathogen-Free Rats on Riboflavin and Thiamine Deficient Diets....Pages 325-332
Nutritional Control of Nematode Development....Pages 333-341
Gnotobiotics and Human Cell Culture....Pages 343-356
Ethylene-Oxide Sterilization of Plastic-Film Isolators: A Six-Year Study of Operational Efficiency....Pages 357-365
Reproduction in Germfree Beagles....Pages 367-371
The Animal Technician: Resident and Transient Microorganisms....Pages 373-382
In Vitro Colony-Forming Cells in the Bone Marrow of Germfree Mice....Pages 383-388
Microbic Interactions in the Gnotobiotic Mouse....Pages 389-398
Germ-Free Mice and Lymphocyte Differentiation....Pages 399-407
Back Matter....Pages 409-423