Genetics of Immunological Diseases

Front Matter....Pages I-XI
Front Matter....Pages 1-1
The Long-Range Mapping of Mammalian Chromosomes....Pages 3-12
The Use of Interspecific Mouse Crosses for Gene Localization: Present Status and Future Perspectives....Pages 13-17
X-Chromosome Gene Order in Different Mus Species Crosses....Pages 18-24
Bayesian Multilocus Linkage Mapping....Pages 25-32
The Rat Gene Map....Pages 33-38
Linkage and Synteny Homologies in Mouse and Man....Pages 39-40
Molecular Analysis of the Aniridia — Wilms’ Tumor Syndrome....Pages 41-46
Approaching the Mouse Steel Locus from Closely Linked Molecular Markers....Pages 47-52
Front Matter....Pages 53-53
Probing Mouse Origins with Random DNA Probes....Pages 55-63
Mouse t Haplotypes: A Tale of Tails and a Misunderstood Selfish Chromosome....Pages 64-69
Contrasting Patterns of Evolution in the Proximal and Distal Regions of the Mouse t Complex....Pages 70-76
From Phenotype to Gene: Molecular Cloning in the Brachyury (T) Locus Region....Pages 77-81
Murine Hox Genes — A Multigene Family....Pages 82-86
Expression of the Homeobox Genes Hox 2.1 and 2.6 During Mouse Development....Pages 87-93
Studies of V(D)J Recombination with Extrachromosomal Substrates....Pages 94-99
Transcription Factors in Terminally Differentiated B Cells....Pages 100-106
Selective and Neutral Evolution in the Murine Igh-V Locus....Pages 107-115
The Organization of the Immunoglobulin Kappa Locus in Mice....Pages 116-129
Conservation of the Organization of the pre-B Cell Specific VpreB1/VpreB2/λ5 Loci in the Genus Mus ....Pages 130-135
The Omega and Iota Surrogate Immunoglobulin Light Chains....Pages 136-139
Front Matter....Pages 53-53
MHC Class I Gene Expression by Tumors: Immunotherapeutic Implications....Pages 140-147
Identification of Regulatory Elements Associated with a Class I MHC Gene....Pages 148-154
Tind, Tsu and Tthy form a Trimolecular Complex Encoded Within the Tsu Locus on Chromosome 12 of the Mouse....Pages 155-162
Front Matter....Pages 163-163
 Lps Gene-Associated Functions....Pages 165-170
The Immunobiology of the T Cell Response to Mls Locus Disparate Stimulator Cells....Pages 171-176
Genetic Analysis of Serologically Undefined Determinants: A T Cell “Clonological” Analysis of the Mls System....Pages 177-182
X-Chromosome Linked Mutations Affecting Mosaic Expression of the Mouse X Chromosome....Pages 183-190
Mosaic Analysis of the Effects of a Novel X-Chromosome Mutation of the Haematopoietic System....Pages 191-196
The scid Mouse Mutant....Pages 197-202
Aberrant Igh Locus Rearrangements in A-MuLV pre B Lines of scid Mice: Evidence for Deregulated D-J Recombination....Pages 203-210
V H Family Usage and Binding Analyses of Polyreactive Monoclonal Autoantibodies Derived from Nonimmunized Adult BALB/c Mice....Pages 211-215
Pleiotropic Effects of Deleterious Alleles at the “Motheaten” Locus....Pages 216-222
Characterization of Mott Cell Hybridomas from Autoimmune “Viable Motheaten” Mutant Mice....Pages 223-226
A Molecular Genetic Approach to gld “Autoimmune” Disease....Pages 227-232
Genetic Analysis of BALB/cJ Subline Resistance to Actively Induced Experimental Allergic Orchitis (EAO) and Experimental Allergic Encephalomyelitis (EAE)....Pages 233-239
Genetic Control of Murine Susceptibility to 3-Methylcholanthrene-Induced T Cell Lymphoma....Pages 240-242
Multigenic Control of Colon Carcinogenesis in Mice Treated with 1,2-Dimethylhydrazine....Pages 243-249
Effect of the Gv-1 Locus on Moloney Ecotropic Murine Leukemia Virus Induced Disease in Inbred Wild Mice....Pages 250-255
Reverse Genetics Approaches for Cloning RIL-1 , a Major Locus Involved in Susceptibility to Leukemia....Pages 256-263
Genetic Map Location of Afr-1 : Results From Four Genetic Crosses....Pages 264-267
Front Matter....Pages 163-163
The Effect of the nude Gene on Plasmacytoma Development in BALB/cAn Mice....Pages 268-275
Organization of the Distal End of Mouse Chromosome 4....Pages 276-288
Susceptibility and Resistance to Plasmacytomagenesis: Possible Role of Genes That Modify Efficiency of Chromatin Repair....Pages 289-294
A Molecular Characterization of BALB/c Congenic C.D2 -Idh-1 b , Lsh r , Rep-1 b , Pep-3 b Mice....Pages 295-300
Analysis of Lsh Gene Expression in Congenic B10.L-Lsh’ Mice....Pages 301-309
Identification of a Linkage Group Including the Bcg Gene by Restriction Fragment Length Polymorphism Analysis....Pages 310-315
Continuous Expression of I-A by Murine Peritoneal Macrophages IS Linked to the Bcg Gene....Pages 316-324
Chromosomal Location of the Gene Determining Resistance to Plasmodium chabaudi AS....Pages 325-328
From Phenotype to Gene: A Molecular Analysis of Complex Loci Involved in Developmental and Immunological Dysregulation....Pages 329-335