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ویرایش:
نویسندگان: V A Tutelyan
سری:
ISBN (شابک) : 9780124058620, 0124058620
ناشر: Elsevier
سال نشر: 2013
تعداد صفحات: 363
زبان: English
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود)
حجم فایل: 4 مگابایت
در صورت تبدیل فایل کتاب Genetically modified food sources: safety assessment and control به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.
توجه داشته باشید کتاب منابع غذایی اصلاح شده ژنتیکی: ارزیابی و کنترل ایمنی نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
Front Cover......Page 1
Genetically Modified Food Sources......Page 4
Copyright Page......Page 5
Contents......Page 6
Authors......Page 10
Editors......Page 12
Reviewers......Page 14
Abbreviations......Page 16
Introduction......Page 18
1 Fundamental Concepts of Development of Genetically Engineered Plants......Page 26
References......Page 37
2 World Production of Genetically Engineered Crops......Page 42
References......Page 48
3 Legislation and Regulation of Production and Sales of Food Derived From Genetically Modified Plants in the Russian Federa .........Page 50
References......Page 54
4 Principles of Human Health Safety Assessment of Genetically Modified Plants Used in the Russian Federation......Page 56
Assessment of Potential for Toxicity......Page 58
Assessment of Potential for Allergenicity......Page 61
4.3 Novel Approaches to Safety Assessment......Page 62
Proteomic Analysis......Page 63
Assessment of Sensitive Biomarkers......Page 64
Conclusion......Page 65
References......Page 66
Introduction......Page 68
Donor Organism......Page 69
Safety Assessment of Soybean Line 40-3-2 Conducted in the Russian Federation......Page 70
Biochemical Composition of Soybean 40-3-2 and Soybean Protein Concentrate......Page 71
Toxicological Assessment of Soybean 40-3-2......Page 75
Assessment of Biochemical Parameters......Page 76
Assessment of Sensitive Biomarkers......Page 79
Hematological Assessments......Page 80
Assessment of Dietary and Nutritional Value of Protein Derived from Transgenic Soybean Line 40-3-2......Page 81
Potential Effect on Humoral Component of Immune System......Page 84
Assessment of a Potential Sensibilization Effect of Transgenic Soybean......Page 85
Potential Effect of Soybean on Susceptibility of Mice to Salmonella typhimurium......Page 86
Mathematical Processing of Experimental Data......Page 87
Results......Page 88
Assessment of Potential Genotoxicity of Transgenic Soybean......Page 89
Assessment of Potential Effect of Transgenic Soybean 40-3-2 on Reproduction......Page 91
Conclusions......Page 93
Method of Genetic Transformation......Page 94
Biochemical Composition of Transgenic Soybean and Soybean Protein Concentrate......Page 95
Assessment of Biochemical Parameters......Page 99
Assessment of Sensitive Biomarkers......Page 103
Morphological Assessment......Page 106
Assessment of Biological Value and Digestibility of Protein Derived from Transgenic Soybean Line A2704-12......Page 107
Potential Effect on Cellular Component of Immune System......Page 110
Potential Effect of Soybean on Susceptibility of Mice to Salmonella typhimurium......Page 111
Assessment of Potential Impact of Transgenic Soybean Line A2704-12 on Immune System in Studies on Rats......Page 112
Assessment of Potential Genotoxicity of Transgenic Soybean Line A2704-12......Page 113
Assessment of Technological Parameters......Page 114
Recipient Organism......Page 115
Biochemical Composition of Transgenic Soybean and Soybean Protein Concentrate......Page 116
Assessment of Proximate Parameters......Page 120
Assessment of Sensitive Biomarkers......Page 122
Morphological Assessments......Page 126
Potential Effect of Soybean on Susceptibility of Mice to Salmonella typhimurium......Page 128
Assessment of Potential Impact of Transgenic Soybean Line A5547-127 on Immune System in Studies on Rats......Page 129
Assessment of Potential Genotoxicity of Transgenic Soybean Line A5547-127......Page 131
Assessment of Technological Parameters......Page 132
Recipient Organism......Page 133
Registration Status of GM Soybean Line MON 89788......Page 134
Assessment of Potential Toxicity of GM Soybean Line MON 89788 in Chronic Experiment in Rats......Page 135
Genotoxicity Studies of GM Soybean Line MON 89788 in Experiment in Mice......Page 145
Assessment of Potential Impact on Immune System of GM Soybean Line MON 89788 in Experiment in Mice......Page 146
Assessment of Potential Allergenicity of GM Soybean Line MON 89788 in Experiments in Rats......Page 148
Assessment of Technological Parameters of Soybean Line MON 89788......Page 149
Recipient Organism......Page 150
Safety Assessment of Transgenic Maize Line GA 21 Conducted in the Russian Federation......Page 151
Biochemical Composition of Maize Grain......Page 152
Toxicological Assessment of Transgenic Maize Line GA 21......Page 154
Assessment of Biochemical Parameters......Page 157
Hematological Assessments......Page 159
Morphological Assessments......Page 160
Potential Effect on Humoral Component of Immune System......Page 161
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 162
Assessment of Potential Impact of Transgenic Maize Line GA 21 on Immune System in Studies on Rats......Page 163
Assessment of Potential Genotoxicity of Transgenic Maize GA 21......Page 164
Assessment of Technological Parameters......Page 166
Method of Genetic Transformation......Page 167
Conclusions......Page 183
Biochemical Composition of Grain......Page 184
Toxicological Assessment of Transgenic Maize Line NK 603......Page 187
Assessment of Sensitive Biomarkers......Page 190
Hematological Assessments......Page 193
Morphological Assessments......Page 194
Potential Effect on Cellular Component of Immune System......Page 195
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 196
Assessment of Potential Impact of Transgenic Maize Line NK 603 on Immune System in Studies on Rats......Page 197
Assessment of Potential Genotoxicicity of Transgenic Maize......Page 198
Assessment of Technological Parameters......Page 199
Method of Genetic Transformation......Page 200
Biochemical Composition of Transgenic Maize Grain......Page 168
Assessment of Proximate Parameters......Page 171
Assessment of Sensitive Biomarkers......Page 174
Hematological Assessments......Page 176
Morphological Assessments......Page 177
Potential Effect on Humoral Component of Immune System......Page 178
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 179
Assessment of Potential Impact of Transgenic Maize Line MON 810 on Immune System in Studies on Rats......Page 180
Assessment of Potential Genotoxicity of Transgenic Maize MON 810......Page 181
Assessment of Technological Parameters......Page 182
Biochemical Composition of Transgenic Maize Grain......Page 201
Toxicological Assessment of Transgenic Maize Line MON 863......Page 204
Assessment of Sensitive Biomarkers......Page 206
Morphological Assessments......Page 209
Potential Effect on Humoral Component of Immune System......Page 210
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 211
Assessment of Potential Impact of Transgenic Maize Line MON 863 on Immune System in Studies on Rats......Page 212
Assessment of Potential Genotoxicity of Transgenic Maize......Page 213
Assessment of Technological Parameters......Page 214
Recipient Organism......Page 215
Global Registration Status of Maize Line Bt11......Page 216
Biochemical Composition of Transgenic Maize Grain......Page 217
Toxicological Assessment of Transgenic Maize Line Bt11......Page 220
Hematological Assessments......Page 222
Potential Effect on Humoral Component of Immune System......Page 225
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 226
Assessment of Potential Impact of Transgenic Maize Line Bt11 on Immune System in Studies on Rats......Page 227
Assessment of Potential Genotoxicicity of Transgenic Maize......Page 228
Assessment of Technological Parameters......Page 229
Donor Organism......Page 230
Safety Assessment of Transgenic Maize Line T25 Conducted in the Russian Federation......Page 231
Biochemical Composition of Transgenic Maize Grain......Page 232
Toxicological Assessment of Transgenic Maize Line T25......Page 234
Assessment of Biochemical Parameters......Page 237
Assessment of Sensitive Biomarkers......Page 238
Morphological Assessments......Page 240
Potential Effect on Humoral Component of Immune System......Page 241
Potential Effect of Transgenic Maize on Susceptibility of Mice to Salmonella typhimurium......Page 242
Assessment of Potential Impact of Transgenic Maize Line T25 on Immune System in Studies on Rats......Page 243
Assessment of Potential Genotoxicicity of Transgenic Maize......Page 244
Assessment of Technological Parameters......Page 245
Method of Genetic Transformation......Page 246
Biochemical Composition of Transgenic Maize Grain......Page 247
Toxicological Assessment of Transgenic Maize Line MON 88017......Page 248
Assessment of Potential Genotoxicity of Transgenic Maize MON 88017......Page 256
Assessment of Potential Impact of Transgenic Maize Line MON 88017 on Immune System in Studies on Mice......Page 258
Assessment of Potential Allergenicity of Transgenic Maize line MON 88017......Page 261
Assessment of Technological Parameters of Maize Line MON 88017......Page 262
Donor Organism......Page 263
Global Registration Status of Maize Line MIR604......Page 264
Toxicological Assessment of Transgenic Maize Line MIR604......Page 265
Assessment of Potential Genotoxicity of Transgenic Maize MIR604......Page 275
Assessment of Potential Impact of Transgenic Maize Line MIR604 on Immune System in Studies on Mice......Page 276
Assessment of Technological Parameters of Maize Line MIR604......Page 278
Donor Organism......Page 280
Global Registration Status of Maize Line 3272......Page 281
Assessment of Potential Toxicity of GM Maize Line 3272 in Experiment in Rats......Page 282
Genotoxicity Assessment of GM Maize Line 3272 in an Experiment in Mice......Page 291
Immunological Assessment of GM Maize Line 3272 in Mice......Page 293
Allergological Assessments of Maize Line 3272 in Experiments in Rats......Page 294
Conclusions......Page 296
Method of Genetic Transformation......Page 297
Biochemical Composition of Transgenic Rice......Page 298
Toxicological Assessment of Transgenic Rice Line LLRICE62......Page 301
Assessment of Biochemical Parameters......Page 302
Hematological Assessments......Page 307
Potential Effect on Humoral Component of Immune System......Page 308
Potential Effect of Transgenic Rice on Susceptibility of Mice to Salmonella typhimurium......Page 309
Assessment of Potential Impact of Transgenic Rice Line LLRICE62 on Immune System in Studies on Rats......Page 310
Assessment of Potential Genotoxicity of Rice Line LLRICE62......Page 311
Conclusions......Page 313
Method of Genetic Transformation......Page 314
Safety Assessment of Transgenic Potato Resistant Against Colorado Potato Beetle Conducted in the Russian Federation......Page 315
Biochemical Composition of Superior NewLeaf Potato......Page 316
Toxicological Assessment of Transgenic Potato......Page 318
Assessment of Biochemical Parameters......Page 320
Assessment of Sensitive Biomarkers......Page 321
Morphological Assessments......Page 323
Potential Effect on Cellular Component of Immune System......Page 324
Assessment of Potential Impact of Transgenic Potato on Immune System in Studies on Rats......Page 325
Assessment of Potential Genotoxicity of Transgenic Potato......Page 327
Conclusions......Page 328
References......Page 329
6.1 Control of Food Products Containing Genetically Modified Ingredients......Page 332
Identification of Recombinant DNA by Polymerase Chain Reaction (PCR) Method......Page 335
Identification of Recombinant DNA with Biological Microchips......Page 338
Quantitative Detection of Recombinant DNA by Real-Time PCR Analysis......Page 340
References......Page 342
7 Monitoring of Food Products Derived from Genetically Modified Organisms of Plant Origin in the Russian Federation......Page 344
References......Page 352
8 Information Service for the Use of Novel Biotechnologies in the Food Industry......Page 354
References......Page 356
Index......Page 358