GeNeDis 2014: Neurodegeneration

Front Matter....Pages i-xiv
Molecular Neuropathology of Alzheimer Dementia and Therapeutic Approaches....Pages 1-1
Toxic Tau Aggregation in AD....Pages 3-9
RNA Binding Proteins and the Genesis of Neurodegenerative Diseases....Pages 11-15
Individual Severity of AD-Type Lesions, Aß Oligomers, and Comorbidity in the Brain Aging....Pages 17-17
The Influence of Immunomodulatory Treatment on the Clinical Course of Multiple Sclerosis....Pages 19-24
Notch Signaling and Ageing....Pages 25-36
Pro-oxidant DNA Breakage Induced by the Interaction of L-DOPA with Cu(II): A Putative Mechanism of Neurotoxicity....Pages 37-51
Superconductivity in Human Body; Myth or Necessity....Pages 53-58
Molecular Genetics of Huntington’s Disease....Pages 59-65
Altered Galectin Glycosylation: Potential Factor for the Diagnostics and Therapeutics of Various Cardiovascular and Neurological Disorders....Pages 67-84
Analytic Considerations and Axiomatic Approaches to the Concept Cell Death and Cell Survival Functions in Biology and Cancer Treatment....Pages 85-105
Possible Role of Resveratrol Targeting Estradiol and Neprilysin Pathways in Lipopolysaccharide Model of Alzheimer Disease....Pages 107-118
Synthesis and Antiepileptic Activity of Schiff’s Bases of Dialkylamino Alkoxy Isatin Derivatives....Pages 119-128
Synthesis and Screening of Biologically Significant 5-Hydroxy Isatin Derivatives for Antioxidant Activity....Pages 129-137
Modeling Neural Circuits in Parkinson’s Disease....Pages 139-147
Neuropathology of Parkinsonism in Alzheimer’s Disease....Pages 149-149
Towards an Expert System for Accurate Diagnosis and Progress Monitoring of Parkinson’s Disease....Pages 151-164
Kinesia Paradoxa: A Challenging Parkinson’s Phenomenon for Simulation....Pages 165-177
Towards the Development of a Device to Improve the Gait of Patients Suffering from Parkinson’s Disease....Pages 179-179
Adaptations in Aquatic Organisms for Increased Sensitivity to Light and Differences from Humans....Pages 181-186
The Impact of Physicochemical and Molecular Properties in Drug Design: Navigation in the “Drug-Like” Chemical Space....Pages 187-194
Advanced Drug Delivery Nanosystems: Perspectives and Regulatory Issues....Pages 195-198
Bio-inspired Chimeric Drug Delivery nano Systems (Chi-DDnSs): Their Fractal Hologram and Regulatory Aspects....Pages 199-200
Amphiphilic Cyclodextrin Nanoparticles for Effective and Safe Delivery of Anticancer Drugs....Pages 201-201
The Innovations in Science and Technology as a Demand for Bio-better Medicines in Europe....Pages 203-208
The Safety of Biological Medicines for Rheumatoid Arthritis....Pages 209-210
The Fractal Analysis as a Complementary Approach to Predict the Stability of Drug Delivery nano Systems (DDnSs) in Aqueous and Biological Media: A Regulatory Proposal or a Dream?....Pages 211-212
Nanothermodynamics Mediates Drug Delivery....Pages 213-220
The Neurodegenerative Potential of Chronic Stress: A Link Between Depression and Alzheimer’s Disease....Pages 221-222
Back Matter....Pages 223-224