Galanin: A New Multifunctional Peptide in the Neuro-endocrine System

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Discovery of galanin....Pages 3-15
On the solution structure of galanin....Pages 17-25
Cloning and expression of porcine and bovine galanin....Pages 27-36
Galanin gene expression....Pages 37-42
Neuroendocrine regulation of galanin gene expression....Pages 43-65
Front Matter....Pages 67-67
Localization of galanin cell bodies in the brain by immunocytochemistry and in situ hybridization histochemistry....Pages 69-92
Distribution of galanin binding sites in the central nervous system....Pages 93-106
Coexistence of galanin-like immunoreactivity with classical transmitters and other neuropeptides in the CNS....Pages 107-116
Galanin: Distribution, ontogeny and expression following manipulation of the endocrine and nervous systems....Pages 117-134
Galanin in enteric neurons....Pages 135-147
Front Matter....Pages 149-149
An overview of galanin’s actions on the endocrine pancreas....Pages 151-176
Galanin and the regulation of insulin secretion....Pages 177-184
Structure-function relationships of galanin....Pages 185-196
Front Matter....Pages 197-197
The galanin receptor: Functional and molecular characterization in the pancreatic beta cell....Pages 199-211
Galanin receptor ligands in the hippocampus: Galanin, N-terminal galanin fragments and analogs....Pages 213-220
Galanin/5-HT interactions in the rat central nervous system. Relevance for depression....Pages 221-235
Galanin inhibits β-cell electrical activity by a G-protein-regulated sulphonylurea-insensitive mechanism....Pages 237-245
Galanin regulation of acetylcholine release and carbachol-stimulated phosphoinositide turnover in rat ventral hippocampus....Pages 247-258
Front Matter....Pages 259-259
Galanin in a parasympathetic ganglion....Pages 261-274
Galanin and gastrointestinal function....Pages 275-286
Front Matter....Pages 259-259
Galanin in primary sensory neurons: Response to lesions....Pages 287-293
Galanin in sensory functions....Pages 295-303
Front Matter....Pages 305-305
Role of galanin in control of hypothalamic pituitary function....Pages 307-319
Role of galanin in prolactin and growth hormone secretion in rats....Pages 321-329
On the interations of galanin within the hypothalamic-pituitary axis of the rat....Pages 331-341
Galanin and the control of growth hormone secretion in man....Pages 343-354
Front Matter....Pages 355-355
The functions of galanin in the septo-hippocampal system of the adult and the aged rat: Electrophysiological and anatomical observations....Pages 357-366
Galanin reduces anoxic release of glutamate by an action on ATP sensitive K+ channels....Pages 367-376
Behavioral actions of galanin and galanin fragments....Pages 377-392
Hypothalamic galanin in relation to feeding behavior and endocrine systems....Pages 393-406
Galanin in the primate CNS and dementing neurologic diseases....Pages 407-417
Senile dementia of the Alzheimer type is accompanied by hypertrophy of galanin axons, reservation of receptors and tissue specific expression of the galanin gene in the nucleus basalis Meynert....Pages 419-427
Back Matter....Pages 429-433