Function and Specificity of γ/δ T Cells: International Workshop, Schloß Elmau, Bavaria, FRG October 14–16, 1990

Front Matter....Pages I-XII
Front Matter....Pages 1-1
Genetic Organization of the Human T Cell Receptor Gamma Locus....Pages 3-9
Front Matter....Pages 11-11
Development of Human T Cells Expressing TCR γδ In Vitro ....Pages 13-15
From the Developmental Expression of γδ T Cell Receptors to the Implications in the Acquisition of Tolerance....Pages 17-23
Culture Conditions Dictate Whether Mouse Fetal Thymus Lobes Generate Predominantly γ/δ or α/βT Cells....Pages 25-28
Preferential Development of γ/δ- Bearing T Cells in Athymic Nude Bone Marrow....Pages 29-32
Developmentally Ordered Expression of γδTCR Vδ7 Subfamily Genes....Pages 33-38
Front Matter....Pages 39-39
Tissue Distribution and Repertoire Selection of Human γδT Cells: Comparison With the Murine System....Pages 41-46
Evidence For Controlled Gene Rearrangements and Cytokine Production During Development of Human TCRγδ+ Lymphocytes....Pages 47-55
Thymic and Extrathymic Development of Human γ/δT Cells....Pages 57-63
Differential Effects of Anti-CD3 Antibodies In Vivo and In Vitro on α β and γ δ T Cell Differentiation....Pages 65-69
The Beginning and the End of the Development of TCRγδ Cells in the Thymus....Pages 71-80
Cyclosporin A (CsA) Prevents the Generation of Mature Thymic α/βT Cells but Spares γ/δ T Lymphocytes....Pages 81-89
Front Matter....Pages 91-91
Lack of Alloantigen-Specific Cytotoxic T Cell Activity in the TCR-γδT Cell Subpopulation of Alloantigen-Immune Chickens....Pages 93-97
Thymic Nurse Cells: a Site for Positive Selection and Differentiation of T Cells....Pages 99-105
Marked Variations in γδT Cell Numbers and Distribution Throughout the Life of Sheep....Pages 107-111
γ/δT-Lymphocyte Subsets in Swine....Pages 113-117
Front Matter....Pages 119-119
Mechanisms of Development of αβ T Cell Antigen Receptor-Bearing Cells in γδ T Cell Antigen Receptor Transgenic Mice....Pages 121-131
Ligand Specificity and Repertoire Development of Murine TCRγδ Cells....Pages 133-139
Front Matter....Pages 141-141
Specificity of Mycobacteria/Self-Reactive γδ Cells....Pages 143-150
Modulation of Murine Self Antigens by Mycobacterial Components....Pages 151-157
Front Matter....Pages 141-141
In Vitro Activation of Human γ/δT Cells by Bacteria: Evidence for Specific Interleukin Secretion and Target Cell Lysis....Pages 159-165
A Dichotomy Between the Cytolytic Activity and Antigen-Induced Proliferative Response of Human γδ T Cells....Pages 167-172
Analysis of Primary T Cell Responses to Intact and Fractionated Microbial Pathogens....Pages 173-178
Function and Specificity of Human Vγ9/Vδ2 T Lymphocytes....Pages 179-182
Daudi Cell Specificity Correlates With the Use of a Vγ9-Vδ2 Encoded TCRγδ....Pages 183-188
TCT.1: A Target Structure for a Subpopulation of Human γ/δ T Lymphocytes....Pages 189-195
Activation and Deactivation of Cloned γ/δT Cells....Pages 197-202
γδ T Cells in Leprosy Lesions....Pages 203-207
Modifications of γδ T Lymphocytes in the Rheumatoid Arthritis Joint....Pages 209-213
Phenotypic and Functional Heterogeneity of Double Negative (CD4-CD8-) αβ TcR+ T Cell Clones....Pages 215-220
Front Matter....Pages 221-221
Specificity of Human T Lymphocytes Expressing a γ/δT Cell Antigen Receptor. Recognition of a Polymorphic Determinant of HLA Class I Molecules by a γ/δ + Clone....Pages 223-227
Antigens and Antigen-Presenting Molecules for γδ T Cells....Pages 229-234
Correlation Between TCRV Gene Usage and Antigen Specificities in Human γδ T Cells....Pages 235-238
Qa-1 Restricted γδ T Cells Can Help B Cells....Pages 239-244
Front Matter....Pages 245-245
CD5 B Cells in the Mouse....Pages 247-251
Front Matter....Pages 253-253
Selection of Vδ+ T Cell Receptors of Intestinal Intraepithelial Lymphocytes is Dependent on Class II Histocompatibility Antigen Expression....Pages 255-267
The Role of Fetal Epithelial Tissues in the Maturation/Differentiation of Bone Marrow-Derived Precursors into Dendritic Epidermal T Cells (DETC) of the Mouse....Pages 269-277
Phenotypic and Functional Characterization of Human TCRγδ+ Intestinal Intraepithelial Lymphocytes....Pages 279-283
A Search for Cells Carrying the γ/δ T Cell Receptor in Mice Infected with Leishmania major ....Pages 285-289
Involvement of γδ T Cells in Respiratory Virus Infections....Pages 291-296