Free Radicals in Synthesis and Biology

Front Matter....Pages i-xx
Captodative Substituent Effects in Synthesis....Pages 1-26
The Influence of gem.-Substitution on the CC-Bond....Pages 27-36
Iodine Atom Transfer Reactions in Organic Synthesis....Pages 37-51
ALKYL Iodides as Source of ALKYL Radicals, useful for Selective Syntheses....Pages 53-69
Introduction of a Single Electron-Withdrawing Carbon-Substituent into π-Deficient N-Heteroarenes by Means of Free-Radical Reactions: Strategies and Synthetic Applications....Pages 71-79
Free Radical Synthesis of Pyridylderivatives: Influence of the Solvent....Pages 81-88
Photoinitiated Radical Reactions of l-(4′-Pyridyl)-4-Pyridone and its N-Protio and N-Methyl Derivatives. Dimerization and Polymerization Reactions....Pages 89-95
Radical Reactions with Organocobalt Complexes....Pages 97-106
New Ways of Generating Stannyl Radicals for Organic Syntheses....Pages 107-114
Silanes as New Reducing Agents in Organic Synthesis....Pages 115-123
ACYL, IMIDOYL, and Other Hetero-Substituted Free Radicals as Intermediates in the Synthesis of Cyclic Organic Compounds....Pages 125-134
Some Studies on Carbonyl Radical Cyclizations and on the Synthesis of 2-Deoxy-β-D-Glycosides by Stereoselective Radical Reactions....Pages 135-143
Stereoselective Formation of Linear AZA-Triquinanes by Three Consecutive Radical Ring Closures....Pages 145-153
Synthetic Applications of Substitution and Addition Reactions Promoted by Cerium(IV) Ammonium Nitrate....Pages 155-185
Use of Homolytic Redox Processes in Organic Syntheses....Pages 187-212
One-Electron Redox Reactions Between Radicals and Molecules. Dominance of Inner-Sphere Mechanisms....Pages 213-231
Electron-Transfer Photosensitization in the Oxidation of Alkyl Aromatics and Heteroaromatics....Pages 233-251
Selenium Radical Ions in Organic Synthesis....Pages 253-262
A Synthetically Useful Source of Alkyl and Acyl Radicals....Pages 263-268
Chlorination by Hypochlorous Acid. Free-Radical Versus Electrophilic Reactions....Pages 269-282
Induced Decomposition of Peroxycompounds in Synthesis: Free Radical Functionalization of Crown Ethers....Pages 283-292
Unwanted Synthesis in Combustion and Pyrolysis; Soot and Dioxins....Pages 293-302
Polar Effects on Radical Addition Reactions: An Ambiphilic Radical....Pages 303-316
The Effect of Temperature in the Reactions of Arenesulphonyl Radicals....Pages 317-324
Synthesis of New 5-Nitroimidazoles Highly Active Against Anaerobes by Substitution Reactions which Proceed via Radical and Radical-Anion Intermediates....Pages 325-333
Detection of Free Radicals in Biochemistry by Electron Spin Resonance Spectroscopy....Pages 335-359
Error in Enzymic Stereospecificity as a Probe for the Occurrence of Radical Intermediates....Pages 361-372
Kinetics of Peroxyl Radical Reactions in Model Biomembranes....Pages 373-390
Rearrangements of Optically Pure Hydroperoxides....Pages 391-406
In Vivo Detection of Free Radical Metabolites....Pages 407-421
The Involvement of Free Radicals in the Metabolism of Drugs....Pages 423-436
The Formation of Fluorescent Pigments due to Radicals in Biological Tissues....Pages 437-460
The Chemistry/Biochemistry Interface in Free-Radical Reactions....Pages 461-468
Back Matter....Pages 469-474
....Pages 475-482