Founder mutations in inherited cardiac diseases in the Netherlands

Content: 
Front Matter....Pages -
Introduction....Pages 1-2
Founder mutations among the Dutch*....Pages 3-12
Recurrent and Founder Mutations in the Netherlands: the Long-QT Syndrome*....Pages 13-19
Founder mutations in the Netherlands: SCN5a 1795insD, the first described arrhythmia overlap syndrome and one of the largest and best characterised families worldwide*....Pages 21-27
Founder mutations in the Netherlands: familial idiopathic ventricular fibrillation and DPP6*....Pages 29-35
Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands*....Pages 37-42
Recurrent and founder mutations in the Netherlands: cardiac Troponin I (TNNI3) gene mutations as a cause of severe forms of hypertrophic and restrictive cardiomyopathy*....Pages 43-50
Recurrent and founder mutations in the Netherlands: mutation p.K217del in troponin T2, causing dilated cardiomyopathy*....Pages 51-57
Recurrent and founder mutations in the Netherlands: the cardiac phenotype of DES founder mutations p.S13F and p.N342D*....Pages 59-68
Recurrent and founder mutations in the Netherlands: Plakophilin-2 p.Arg79X mutation causing arrhythmogenic right ventricular cardiomyopathy/dysplasia*....Pages 69-79
Recurrent and founder mutations in the Netherlands – Phospholamban p.Arg14del mutation causes arrhythmogenic cardiomyopathy*....Pages 81-87
Recurrent and founder mutations in the Netherlands: Extensive clinical variability in Marfan syndrome patients with a single novel recurrent fibrillin-1 missense mutation*....Pages 89-94
Founder mutations in the Netherlands: geographical distribution of the most prevalent mutations in the low-density lipoprotein receptor and apolipoprotein B genes*....Pages 95-102