Extracellular Nucleotides and Nucleosides: Release, Receptors, and Physiological & Pathophysiological Effects

Content: 
Series Editors
Page ii

Contributors
Pages xiii-xv

Foreword: Extracellular Nucleotide and Nucleoside Signaling: First Principles
Pages xvii-xxii
Erik M Schwiebert

Preface
Pages xxiii-xxiv

Introduction: ATP and Its Metabolites as Potent Extracellular Agents Original Research Article
Pages 1-27
Geoffrey Burnstock

Cellular Mechanisms and Physiology of Nucleotide and Nucleoside Release from Cells: Current Knowledge, Novel Assays to Detect Purinergic Agonists, and Future Directions Original Research Article
Pages 31-58
Erik M Schwiebert, Akos Zsembery, John P Geibel

Molecular and Biological Properties of P2Y Receptors Original Research Article
Pages 59-96
Eduardo R Lazarowski

Extracellular ATP-Gated P2X Purinergic Receptor Channels Original Research Article
Pages 97-150
Amanda Taylor Boyce, Erik M Schwiebert

Molecular and Cell Biology of Adenosine Receptors Original Research Article
Pages 151-181
B.R Cobb, J.P Clancy

Relating the Structure of ATP-Gated Ion Channel Receptors to Their Function Original Research Article
Pages 183-202
Terrance M Egan, Keisuke Migita, Mark M Voigt

Epithelial Purinergic Receptors and Signaling in Health and Disease Original Research Article
Pages 205-241
Gavin M Braunstein, Erik M Schwiebert

Nucleotide Release and Purinergic Signaling in the Vasculature Driven by the Red Blood Cell Original Research Article
Pages 243-268
Randy S Sprague, Mary L Ellsworth, Hans H Detrich

A Purine Signal for Functional Hyperemia in Skeletal and Cardiac Muscle Original Research Article
Pages 269-305
Thomas Forrester

Purinergic Receptors in the Nervous System Original Research Article
Pages 307-368
Geoffrey Burnstock

Purinergic (P2) Receptors in the Kidney Original Research Article
Pages 369-394
Jens Leipziger, Matthew A Bailey, Robert J Unwin

Purinergic Receptors and Hepatobiliary Function Original Research Article
Pages 395-414
Andrew P Feranchak, J.Gregory Fitz

ATP in the Treatment of Advanced Cancer Original Research Article
Pages 415-452
Edward H Abraham, Anna Y Salikhova, Eliezer Rapaport

Purinergic Receptors in the Glomerulus and Vasculature of the Kidney Original Research Article
Pages 453-478
Edward W. Inscho

Index
Pages 479-497