Experimental Cardiac Hypertrophy and Heart Failure

Front Matter....Pages I-1
Quantitative aspects of the calcium concept of excitation contraction coupling — a critical evaluation....Pages 2-12
Calcium-induced calcium release in sarcoplasmic reticulum vesicles purified from rabbit fast skeletal muscle....Pages 13-17
Ca 2+ control of actin-myosin interaction....Pages 18-25
Investigations on glycerinated cardiac muscle fibres in relation to the problem of regulation of cardiac contractility — effects of Ca ++ and c-AMP)....Pages 26-33
The rate-limiting step in muscle contraction....Pages 34-39
Calcium activation and maximum unloaded shortening velocity. Investigations on glycerinated skeletal and heart muscle preparations....Pages 40-46
Some aspects on the regulation of carbohydrate and lipid metabolism in cardiac tissue....Pages 47-56
The influence of various precursors on the concentration of energy-rich phosphates and pyridine nucleotides in cardiac tissue and its possible meaning for anoxic survival....Pages 57-61
Effects of carbocromene on performance and oxidation of FFA and glucose in isolated atria....Pages 62-65
Prospects of X-ray microanalysis in the study of pathophysiology of myocardial contraction....Pages 66-72
Alterations in excitation of mammalian myocardium as a function of chronic loading and their implications in the mechanical events....Pages 73-80
Subcellular changes during cardiac hypertrophy and heart failure due to bacterial endocarditis....Pages 81-91
Characterization of cardiac microsomes from spontaneously hypertonic rats....Pages 92-96
Functional alterations of cardiac subcellular structures during energy deficiency in relation to the metabolic state of the heart muscle cell....Pages 97-104
Aorto-caval fistula in the rat. An experimental model of heart volume overloading....Pages 105-108
Quantitative ultrastructure of the myocardium in chronic aortic valve disease....Pages 109-117
Differences between transmitter depletion in human heart hypertrophy and experimental cardiac hypertrophy in Goldblatt rats....Pages 118-125
Alterations of substances (DNA, myoglobin, myosin, protein) in experimentally induced cardiac hypertrophy and under the influence of drugs (isoproterenol, cytostatics, strophanthin)....Pages 126-138
Increased uracil nucleotide metabolism during the induction of cardiac hypertrophy by β-stimulation in rats....Pages 139-142
Experimental systolic and diastolic overloading in rats: total proteins turnover rate. Enzymatic and structural properties of myosin....Pages 143-148
Mechanism of physiologic versus pathologic ventricular hypertrophy process: Enhanced or depressed myosin ATPase activity and contractility governed by type, degree and duration of inciting stress....Pages 149-156
Cooperative effects of calcium on myofibrillar ATPase of normal and hypertrophied heart....Pages 157-162
The myofibrillar ATPase activity and the substructure of myosin in the hypertrophied left ventricle of the rat....Pages 163-170
Mitochondrial Proliferation in Cardiac Hypertrophy....Pages 171-178
The functional significance of altered tension dependent heat in thyrotoxic myocardial hypertrophy....Pages 179-184
Oxygen consumption and substrate uptake of the hypertrophied rat heart in situ....Pages 185-192
Intracellular oxygen utilization in mechanically overloaded rat heart....Pages 193-198
Myocardial flow reserve in experimental cardiac hypertrophy....Pages 199-206
Significance of the hexose monophosphate shunt in experimentally induced cardiac hypertrophy....Pages 207-213
The behavior of some enzymes of the hypertrophied and postnatally developing myocardium of the rat....Pages 214-220
Immunological parameters in patients with congestive cardiomyopathy....Pages 221-222
On the mechanism of elevation of cardiac muscle functional capabilities in adaptation to exercise....Pages 223-233
Systolic stress, coronary hemodynamics and metabolic reserve in experimental and clinical cardiac hypertrophy....Pages 234-243
Contracture type and fibrosis type of decreased myocardial distensibility. Different changes in elasticity of myocardium in hypoxia and hypertrophy....Pages 244-252
Elastic and contractile properties of the myocardium in experimental cardiac hypertrophy of the rat Methodological and pathophysiological considerations....Pages 253-261
Comparative studies of ventricular ejection phase parameters for the detection of impaired cardiac function....Pages 262-269
Maximum contractility of the experimentally hypertrophied heart in situ and survival of the acute coronary occlusion....Pages 270-278
Influence of acute alcohol intoxication on the left ventricular pressure-volume relations of the rat heart....Pages 279-280
The contribution of neural pathways to blood volume homeostasis in the subhuman primate....Pages 281-288
Electrolyte and water balance in cardiac insufficiency. Recent clinical and experimental data....Pages 289-293
Back Matter....Pages 294-305