Excitatory Amino Acids

Front Matter....Pages i-xvii
Twenty-five Years of Excitatory Amino Acid Research....Pages 1-39
Regulatory Aspects of Endogenous Glutamate in Brain....Pages 41-46
Metabolic Precursors of the Transmitter Pools of Glutamate and Aspartate....Pages 47-56
Glia–Neuronal Interrelationships in the Metabolism of Excitatory Amino Acids....Pages 57-66
The Compartmentation and Turnover of Glutamate and GABA: A Better Understanding by the Use of Drugs....Pages 67-83
Immunocytochemical Localization of Enzymes Involved in the Metabolism of Excitatory Amino Acids....Pages 85-100
Antibodies for the Localization of Excitatory Amino Acids....Pages 101-116
Identification of Pathways for Acidic Amino Acid Transmitters and Search for New Candidates: Sulphur-containing Amino Acids....Pages 117-129
Excitatory Amino Acids as Transmitters in the Olfactory System....Pages 131-142
Amino Acids as Excitatory Transmitters in the Retina....Pages 143-157
Mechanisms of Reuptake of Neurotransmitters from the Synaptic Cleft....Pages 159-172
Glutamate Transport in the Synaptic Vesicle....Pages 173-195
Presynaptic Receptors for Excitatory Amino Acid Transmitters....Pages 197-207
Some Comparative Aspects of the Pharmacology of Excitatory Amino Acids in Spinal Cord and Hippocampus....Pages 209-226
Pharmacology of Excitatory Amino Acids on Spinal Cord Neurones....Pages 227-238
L-Glutamic Acid Receptors on Locust Muscle: Pharmacological Properties and Single Receptor Channel Studies....Pages 239-249
Discrimination of Excitatory Amino Acid Receptor Sub-types Using Radioligand Binding Techniques....Pages 251-262
Anatomical Organization of NMDA, Kainate and Quisqualate Receptors....Pages 263-277
Functions and Regulations of Glutamate Receptors....Pages 279-299
Functional Reconstitution of Binding-ion Channel Activity and Immunochemical Characterization of Brain Synaptic Membrane Glutamate Binding Protein....Pages 301-321
Analysis of Excitatory Amino Acid Receptor Function with 22Na+ Fluxes in Brain Slices....Pages 323-335
Glutamate Receptors and Glutamate Corticofugal Pathways....Pages 337-354
The Neuropharmacology of Quinolinic Acid and the Kynurenines....Pages 355-365
Endogenous Excitotoxins: Focus on Quinolinic Acid....Pages 367-380
Interactions of Acidic Peptides: Excitatory Amino Acid Receptors....Pages 381-396
Extracellular Concentration of Excitatory Amino Acids: Effects of Hyperexcitation, Hypoglycemia and Ischemia....Pages 397-408
Excitatory Amino Acids: Approaches to Rational Anticonvulsant Therapy....Pages 409-422
Back Matter....Pages 423-436
....Pages 437-508