Evaluating and Standardizing Therapeutic Agents, 1890-1950

Cover......Page 1
Contents......Page 6
List of Figures......Page 8
List of Tables......Page 10
Acknowledgements......Page 11
Notes on Contributors......Page 12
Introduction: Evaluating and Standardizing Therapeutic Agents, 1890–1950......Page 16
1 Paul Ehrlich’s Standardization of Serum: Wertbestimmung and Its Meaning for Twentieth-Century Biomedicine......Page 28
2 Evaluation as a Practical Technique of Administration: The Regulation and Standardization of Diphtheria Serum......Page 46
3 From Diphtheria to Tetanus: The Development of Evaluation Methods for Sera in Imperial Germany......Page 67
4 The Construction of a Culture of Standardization at the Institut Pasteur (1885–1900)......Page 86
5 Quality Control and the Politics of Serum Production in France......Page 104
6 ‘The Geneva serum is excellent!’ Autonomy and Isolation in the Swiss Cantons During the Early Years of Diphtheria Serum: The Case of Geneva......Page 120
7 The State, the Serum Institutes and the League of Nations......Page 133
8 Questions of Quality: The Danish State Serum Institute, Thorvald Madsen and Biological Standardization......Page 154
9 ‘The Wright Way’: The Production and Standardization of Therapeutic Vaccines in Britain, 1902–13......Page 168
10 The Visible Industrialist: Standards and the Manufacture of Sex Hormones......Page 189
11 ‘We need for digitalis preparations what the state has established for serumtherapy …’ From Collecting Plants to International Standardization: The Case of Strophanthin, 1900–38......Page 217
12 Changing Regulations and Risk Assessments: National Responses to the Introduction of Inactivated Polio Vaccine in the UK and West Germany......Page 244
13 Standardization Before Biomedicine: On Early Forms of Regulatory Objectivity......Page 267
E......Page 277
K......Page 278
P......Page 279
W......Page 280
Z......Page 281