Epigenetics

CoverPage_978-0879697310_0879697318......Page 1
FrontMatter......Page 2
TitlePage......Page 4
CopyRight......Page 5
Participants_Lists......Page 6
Participants_Pictures......Page 16
Forward......Page 24
Sponsors......Page 25
Contents......Page 26
Ch01_Mechanism of Mouse Germ Cell Specification......Page 30
Ch02_Epigenetic Mechanisms in Early Mammalian Development......Page 40
Ch03_Nuclear Cloning, Epigenetic Reprogramming, and Cellular Differentiation......Page 48
Ch04_Chromosome Loops, Insulators, and Histone Methylation......Page 58
CH05_Genomic Imprinting--Antagonistic Mechanisms in the Germ Line and Early Embryo......Page 68
Ch06_Drosophila Su(Hw) Regulates an Evolutionarily Conserved Silencer of Mouse H19......Page 76
Ch07_The Air Noncoding RNA--An Imprinted cis-silencing Transcript......Page 84
Ch08_The (Dual) Origin of Epigenetics......Page 96
Ch09_Sex and X Chromosome-wide Repression in Caenorhabditis elegans......Page 100
Ch10_Targeting Dosage Compensation to the X Chromosome of Drosophila Males......Page 110
Ch11_Mammalian X Chromosome Inactivation--An Epigenetics Paradigm......Page 118
Ch12_A Continuity of X-Chromosome Silence from Gamete to Zygote......Page 132
Ch13_Reading the DNA Methylation Signal......Page 142
Ch14_Genome Defense and DNA Methylation in Neurospora......Page 148
Ch15_Role of De Novo DNA Methyltransferases in Initiation of Genomic Imprinting......Page 154
Ch16_Gene Repression Paradigms in Animal Cells......Page 160
Ch17_Control of Development and Transposon Movement by DNA Methylation......Page 168
Ch18_DNA Methylation of the Endogenous PAI Genes in Arabidopsis......Page 174
Ch19_Induced and Natural Epigenetic Variation......Page 184
Ch20_Linking Covalent Histone Modifications to Epigenetics......Page 190
Ch21_Steps Toward Understanding the Inheritance of Repressive Methyl-Lysine Marks in Histones......Page 200
Ch22_Noncovalent Modification of Chromatin......Page 212
Ch23_Acetylation of Yeast Histone H4 Lysine 16......Page 222
Ch24_Histone Deposition Proteins......Page 230
Ch25_Trilogies of Histone Lysine Methylation as Epigenetic Landmarks......Page 238
Ch26_Histone H3 Amino-Terminal Tail Phosphorylation and Acetylation......Page 248
Ch27_Structural Characterization of Histone H2A Variants......Page 256
Ch28_Epigenetics, Histone H3 Variants, and the Inheritance of Chromatin States......Page 264
Ch29_Chromatin Boundaries and Chromatin Domains......Page 274
Ch30_Do Higher-Order Chromatin Structure and Nuclear Reorganization vs Hox Gene Expression......Page 280
Ch31_SIR1 and the Origin of Epigenetic States in Saccharomyces cerevisiae......Page 288
Ch32_Analyzing Heterochromatin Formation Using Chromosome 4 of Drosophila......Page 296
Ch33_Two Distinct Nucleosome Assembly Pathways......Page 302
Ch34_The Chromatin Accessibility Complex- Chromatin Dynamics through Nucleosome Sliding......Page 310
Ch35_Histone H2B Ubiquitylation and Deubiquitylation in Genomic Regulation......Page 318
Ch36_Polycomb Silencing Mechanisms in Drosophila......Page 330
Ch37_Mechanism of Polycomb Group Gene Silencing......Page 338
Ch38_Emerging Roles of Polycomb Silencing in X-Inactivation and Stem Cell Maintenance......Page 348
Ch39_The Function of Telomere Clustering in Yeast- The Circe Effect......Page 356
Ch40_Genetic Instability in Aging Yeast- A Metastable Hyperrecombinational State......Page 368
Ch41_Restructuring the Genome in Response to Adaptive Challenge......Page 378
Ch42_Poetry of b1 Paramutation- cis- and trans-Chromatin Communication......Page 384
Ch43_RNA Silencing Pathways in Plants......Page 392
Ch44_Transposons, Tandem Repeats, and the Silencing of Imprinted Genes......Page 400
Ch45_Transposon Silencing and Imprint Establishment in Mammalian Germ Cells......Page 410
Ch46_RNA Interference, Heterochromatin, and Centromere Function......Page 418
Ch47_RNA Interference, Transposon Silencing, and Cosuppression in the C elegans......Page 426
Ch48_Plant RNA Interference in Vitro......Page 432
Ch49_A Conserved microRNA Signal Specifies Leaf Polarity......Page 438
Ch50_RNA interference and epigenetic control of heterochromatin assembly......Page 448
Ch51_Regulation of Caenorhabditis elegans RNA Interference by the daf-2 Insulin Stress......Page 458
Ch52_Interrelationship of RNA Interference and Transcriptional Gene Silencing in Drosophila......Page 462
Ch53_Functional Identification of Cancer-relevant Genes through Large-Scale RNA Interference Screens in Mammalian Cells......Page 468
Ch54_The New Field Of Epigenomics- Implications for Cancer......Page 476
Ch55_Epigenetic Regulation in the Control of Flowering......Page 486
Ch56_Transposons and Tandem Repeats Are Not Involved in the Control of Genomic Imprinting......Page 494
Ch57_Toward Molecular Understanding of Polar Overdominance at the Ovine Callipyge Locus......Page 506
Ch58_Dscam-mediated Self- versus Non-Self-Recognition by Individual Neurons......Page 514
Ch59_Prions of Yeast Are Genes Made of Protein- Amyloids and Enzymes......Page 518
Ch60_A Possible Epigenetic Mechanism for the Persistence of Memory......Page 526
Ch61_An Epigenetic Hypothesis for Human Brain Laterality, Handedness, and Psychosis Development......Page 528
Ch62_Summary Epigenetics—from Phenomenon to Field......Page 536