Epigenetic Biomarkers and Diagnostics

Content: 
Front Matter,Copyright,List of Contributors,PrefaceEntitled to full textChapter 1 - Epigenetic Biomarkers: New Findings, Perspectives, and Future Directions in Diagnostics, Pages 1-18, José Luis García-Giménez, Toshikazu Ushijima, Trygve O. Tollefsbol
Chapter 2 - The Importance of Biobanks in Epigenetic Studies, Pages 19-35, Lorena Peiró-Chova, Olga Bahamonde Ponce, Carolina Abril-Tormo, Jacobo Martínez-Santamaría, José Antonio López-Guerrero, Peter H.J. Riegman
Chapter 3 - Epigenetic Mechanisms as Key Regulators in Disease: Clinical Implications, Pages 37-66, Abdelhalim Boukaba, Fabian Sanchis-Gomar, José Luis García-Giménez
Chapter 4 - The Evolution of New Technologies and Methods in Clinical Epigenetics Research, Pages 67-89, Tandy L.D. Petrov, Nicole C. Riddle
Chapter 5 - Biomarkers and Methodologies for Monitoring Epigenetic Drug Effects in Cancer, Pages 91-118, Marianne B. Treppendahl, Lasse Sommer Kristensen, Kirsten Grønbæk
Chapter 6 - Genome-Wide Techniques for the Study of Clinical Epigenetic Biomarkers, Pages 119-135, Eneda Toska, F. Javier Carmona Sanz
Chapter 7 - Sequenom MassARRAY Technology for the Analysis of DNA Methylation: Clinical Applications, Pages 137-153, Enrique J. Busó, Marisa Iborra
Chapter 8 - The Role of Methylation-Specific PCR and Associated Techniques in Clinical Diagnostics, Pages 155-173, Fang Zhao, Bharati Bapat
Chapter 9 - Pyrosequencing and Its Application in Epigenetic Clinical Diagnostics, Pages 175-194, Ana-Maria Florea
Chapter 10 - Mass Spectrometry for the Identification of Posttranslational Modifications in Histones and Its Application in Clinical Epigenetics, Pages 195-214, Roberta Noberini, Alessandro Cuomo, Tiziana Bonaldi
Chapter 11 - High-Throughput Analysis of Noncoding RNAs: Implications in Clinical Epigenetics, Pages 215-238, Valerio Costa, Maria R. Matarazzo, Miriam Gagliardi, Roberta Esposito, Alfredo Ciccodicola
Chapter 12 - Circulating Noncoding RNAs as Clinical Biomarkers, Pages 239-258, Francesco Russo, Flavia Scoyni, Alessandro Fatica, Marco Pellegrini, Alfredo Ferro, Alfredo Pulvirenti, Rosalba Giugno
Chapter 13 - DNA Methylation Biomarkers in Lung Cancer, Pages 259-273, Juan Sandoval, Paula Lopez Serra
Chapter 14 - DNA Methylation Alterations as Biomarkers for Prostate Cancer, Pages 275-296, João Ramalho-Carvalho, Rui Henrique, Carmen Jerónimo
Chapter 15 - DNA Methylation in Breast Cancer, Pages 297-312, Raimundo Cervera, Alberto Ramos, Ana Lluch, Joan Climent
Chapter 16 - DNA Methylation in Obesity and Associated Diseases, Pages 313-329, Ana B. Crujeiras, Angel Diaz-Lagares
Chapter 17 - DNA Methylation Biomarkers in Asthma and Allergy, Pages 331-350, Avery DeVries, Donata Vercelli
Chapter 18 - DNA Methylation for Prediction of Adverse Pregnancy Outcomes, Pages 351-376, Deepali Sundrani, Vinita Khot, Sadhana Joshi
Chapter 19 - Epigenetics in Infectious Diseases, Pages 377-400, Genevieve Syn, Jenefer M. Blackwell, Sarra E. Jamieson
Chapter 20 - DNA Methylation in Neurodegenerative Diseases, Pages 401-415, Sahar Al-Mahdawi, Sara Anjomani Virmouni, Mark A. Pook
Chapter 21 - The Histone Code and Disease: Posttranslational Modifications as Potential Prognostic Factors for Clinical Diagnosis, Pages 417-445, Nicolas G. Simonet, George Rasti, Alejandro Vaquero
Chapter 22 - Histone Posttranslational Modifications and Chromatin Remodelers in Prostate Cancer, Pages 447-465, Filipa Quintela Vieira, Diogo Almeida-Rios, Inês Graça, Rui Henrique, Carmen Jerónimo
Chapter 23 - Histone Posttranslational Modifications in Breast Cancer and Their Use in Clinical Diagnosis and Prognosis, Pages 467-477, Luca Magnani, Annita Louloupi, Wilbert Zwart
Chapter 24 - Histone Variants and Posttranslational Modifications in Spermatogenesis and Infertility, Pages 479-496, Juan Ausio, Yinan Zhang, Toyotaka Ishibashi
Chapter 25 - Circulating Histones and Nucleosomes as Biomarkers in Sepsis and Septic Shock, Pages 497-517, José Luis García Giménez, Carlos Romá Mateo, Marta Seco Cervera, José Santiago Ibañez Cabellos, Federico V. Pallardó
Chapter 26 - Chromatin Landscape and Epigenetic Signatures in Neurological Disorders: Emerging Perspectives for Biological and Clinical Research, Pages 519-537, Pamela Milani, Ernest Fraenkel
Chapter 27 - MicroRNA Deregulation in Lung Cancer and Their Use as Clinical Tools, Pages 539-555, Paula Lopez-Serra, Juan Sandoval
Chapter 28 - Circulating Nucleic Acids as Prostate Cancer Biomarkers, Pages 557-585, Claire E. Fletcher, Ailsa Sita-Lumsden, Akifumi Shibakawa, Charlotte L. Bevan
Chapter 29 - MicroRNAs in Breast Cancer and Their Value as Biomarkers, Pages 587-612, Olafur Andri Stefansson
Chapter 30 - MicroRNAs in Bone and Soft Tissue Sarcomas and Their Value as Biomarkers, Pages 613-642, Tomohiro Fujiwara, Yu Fujita, Yutaka Nezu, Akira Kawai, Toshifumi Ozaki, Takahiro Ochiya
Chapter 31 - miRNAs in the Pathophysiology of Diabetes and Their Value as Biomarkers, Pages 643-661, Eoin Brennan, Aaron McClelland, Shinji Hagiwara, Catherine Godson, Phillip Kantharidis
Index, Pages 663-680