Endogenous and Exogenous Opiate Agonists and Antagonists. Proceedings of the International Narcotic Research Club Conference, June 11–15, 1979, North Falmouth, Massachusetts, USA

Content: 
Related Pergamon Books, Page ii
Front Matter, Page iii
Copyright, Page iv
Preface, Page xvii, E. Leong Way
WHO ROLE IN DRUG ADDICTION, Pages xix-xx, Inayat Khan
PRIMARY STRUCTURE AND SPECIFICITY IN ENDOGENOUS OPIOID PEPTIDES, Pages 1-4, Derek G. Smyth
SYNTHETIC βh-ENDORPHIN ANALOGS MODIFIED AT THE N-TERMINAL, POSITIONS 2 AND 5, Pages 5-8, J.-K. Chang, R.E. Chipkin, J.M. Stewart
CHEMICAL FEATURES FOR OPIATE AGONIST AND ANTAGONIST, Pages 9-12, M. Nozaki, K. Kamikubo, M. Niwa, H. Fujimura, E. Imai, Y. Suzuki, M. Hori
THE SYNTHESIS AND AGONIST ACTIVITY OF SOME 14β-SUBSTITUTED MORPHINE AND CODEINE DERIVATIVES, Pages 13-16, Peter Osei-Gyimah, Sydney Archer
4-ARYL-4-AMINOCYCLOHEXANONE DERIVATIVES: A CHEMICALLY NOVEL SERIES OF ANALGESICS INCLUDING OPIOID ANTAGONISTS AND EXTREMELY POTENT AGONISTS, Pages 17-21, Philip F. VonVoigtlander, Daniel Lednicer, Richard A. Lewis, David D. Gay
N-METHYLBENZOMORPHANALKANONES. A COMPARISON OF THEIR STRUCTURE-ACTIVITY RELATIONSHIPS AND X-RAY CRYSTAL STRUCTURE WITH THOSE OF THE BRIDGED THEBAINE DERIVATIVES. AN OPIATE RECEPTOR PROPOSAL, Pages 23-24, William F. Michne
QUANTUM CHEMICAL STUDIES OF NOVEL 4-PHENYLPIPERIDINE OPIATES WITH ANTAGONIST ACTIVITY, Pages 25-28, Stanley Burt, Gilda Loew
STRUCTURE-FUNCTION STUDIES IN PEPTIDES RELATED TO THE β-LPH61-64 SEQUENCE, Pages 29-32, J.D. Bower, B.K. Handa, A.C. Lane, J.A.H. Lord, G. Metcalfe, B.A. Morgan, M.J. Rance, P.M. Richards, G.F.C. smith
Enkephalin Analogs and Physical Dependence, Pages 33-36, Eddie Wei
INTERACTION OF A MODEL OPIATE ANIONIC RECEPTOR SITE WITH N-SUBSTITUENTS OF RIGID OPIATES: PCILO ENERGY CALCULATIONS, Pages 39-42, Gilda Loew, Stanley Burt
EFFECTS OF MONOVALENT CATIONS ON CEREBROSIDE SULFATE BINDING TO OPIATE AGONISTS AND ANTAGONISTS, Pages 43-45, Tae Mook Cho, Jung Sook Cho, Horace H. Loh, E. Leong Way
OPIATE BINDING AND CEREBROSIDE SULFATES IN BRAIN AND LUNG OF DEVELOPING CHICK, Pages 47-50, Giovanni Marzullo, Arnold J. Friedhoff
OPIATE RECEPTOR BINDING STUDIES INFLUENCE OF A REVERSIBLE SULFHYDRYL REAGENT, Pages 51-54, Mahmoud S. Ahmed, William L. Byrne
ASCORBATE DESTRUCTION OF OPIOID STEREOSPECIFIC BINDING; EVIDENCE FOR RECEPTOR REGULATION BY MEMBRANE LIPID, Pages 55-58, Claud E. Dunlap III, Frances M. Leslie, Brian M. Cox
THE STUDY OF ENKEPHALIN-RECEPTOR INTERACTION USING ISOSTERICALLY MODIFIED ANALOGUES, Pages 59-62, M. Szelke, D. Hudson, R. Sharpe, P. Tien, A. Hallett
SEASONAL VARIATION IN THE APPARENT NUMBER OF 3H-NALOXONE BINDING SITES, Pages 63-66, Ellen E. Codd, William L. Byrne
EVIDENCE FOR HALF-OF-THE-SITES REACTIVITY IN THE BINDING OF OPIATE AGONISTS AND ANTAGONISTS TO THE OPIATE RECEPTOR, Pages 67-70, William L. Byrne, Ellen E. Codd
EFFECTS OF ANESTHETICS IN VITRO ON BRAIN RECEPTORS FOR OPIATES, SPIROPERIDOL AND OUABAIN, Pages 71-74, Frank S. LaBella, Carl Pinsky, Viktor Havlicek, Gary Queen
OPIOID AGONISTS AND ANTAGONISTS: ACTION ON MULTIPLE OPIATE RECEPTORS, Pages 75-78, Michael Wüster, Rudiger Schulz, Albert Herz
STUDY OF OPIATE RECEPTOR MULTIPLICITY IN RATS BY IN VIVO BINDING ASSAYS, Pages 79-82, David C. Perry, Kary B. Mullis, Wolfgang Sadee
COMPARISON OF THE BINDING CHARACTERISTICS OF OPIATES AND OPIOID PEPTIDES, Pages 83-85, Maureen G.C. Gillan, Stewart J. Paterson, Hans W. Kosterlitz
TYPE 1 AND TYPE 2 OPIATE RECEPTORS: A SUBCLASSIFICATION SCHEME BASED UPON GTP'S DIFFERENTIAL EFFECTS ON BINDING, Pages 87-90, Candace B. Pert, Duncan Taylor
SCATCHARD ANALYSIS OF OPIATE RECEPTOR BINDING, Pages 91-94, Steven V. Fischel, Fedor Medzihradsky
MULTIPLE OPIATE BINDING SITES IN RAT BRAIN: DIFFERENTIAL DISPLACEMENT OF 3H-NALOXONE BINDING BY DIFFERENT OPIATE LIGANDS, Pages 95-98, William A. Hewlett, Huda Akil, Jack D. Barchas
PHENOXYBENZAMINE, AN IRREVERSIBLE LIGAND OF OPIOID RECEPTORS IN VIVO ?, Pages 99-102, J. JACOB, K. RAMABADRAN, J.C. ROUSSELLE, P.E. CHABRIER
TOLERANCE, CROSS-TOLERANCE AND DEPENDENCE TO μ AND K AGONISTS IN VIVO AND IN VITRO, Pages 103-106, Susan J. Ward, Colin F.C. Smith, Geoffrey Metcalf, John M.H. Rees
SPECIFIC PROTECTION OF μ- AND δ-BINDING SITES IN GUINEA-PIG BRAIN, AGAINST THE INHIBITORY EFFECT OF PHENOXYBENZAMINE, BY AGONISTS PREFERENTIALLY INTERACTING WITH μ- OR δ-SITES, Pages 107-108, Linda E. Robson, Hans W. Kosterlitz
LIGAND SPECIFICITY OF OPIOID BINDING SITES IN BRAIN AND PERIPHERAL TISSUES, Pages 109-112, Frances M. Leslie, Charles Chavkin, B.M. Cox
MULTIPLE OPIATE RECEPTORS: EVIDENCE FOR MEDIATION OF ANALGESIA BY A SUBPOPULATION OF RECEPTORS, Pages 113-116, Gavril W. Pasternak, Steven R. Childers, Solomon H. Snyder
ABNORMAL BRAIN OPIATE MECHANISMS IN SCHIZOPHRENIA, Pages 117-120, T.D. Reisine, N.W. Pedigo, P. Regan, N. Ling, H.I. Yamamura
CHARACTERIZATION OF 3H-β-ENDORPHIN BINDING IN RAT BRAIN, Pages 123-126, Huda Akil, William Hewlett, Jack D. Barchas, Choh Hao Li
α-MSH IN BRAIN β-ENDORPHIN NEURONS, AND OTHER NEURONS AS WELL, Pages 127-130, Stanley J. Watson
OPIOID RECEPTOR AUTORADIOGRAPHY IN BRAINS OF HUMANS AND ANIMALS, Pages 131-134, W. Scott Young III, Michael J. Kuhar
DEVELOPMENT OF OPIATE TOLERANCE/DEPENDENCE IN THE GUINEA-PIG MYENTERIC PLEXUS AND THE MOUSE VAS DEFERENS, Pages 135-138, Rüdiger Schulz, Elisabeth Faase, Peter Illes, Michael Wüster
IONTOPHORETICALLY APPLIED MORPHINE AND MET-ENKEPHALIN MAY INTERACT WITH DIFFERENT RECEPTORS IN THE BRAIN, Pages 139-142, Walter Zieglgänsberger, Jonathan P. Fry, Lynn A. Lambert
LOCAL AND CNS-MEDIATED EFFECTS OF MORPHINE AND NARCOTIC ANTAGONISTS ON GASTROINTESTINAL PROPULSION IN RATS, Pages 143-146, L. Manara, G. Bianchi, P. Ferretti, E. Monferini, D. Strada, A. Tavani
CENTRAL EFFECTS OF β-ENDORPHIN ON INTESTINAL TRANSIT, Pages 147-149, Thomas F. Burks
EFFECTS OF 6-HYDROXYDOPAMINE AND 5,7-DIHYDROXYTRYPTAMINE BRAINSTEM LESIONS ON MORPHINE ANALGESIA IN THE RAT, Pages 151-154, Agu Pert, V. John Massari, Yousef Tizabi, Thomas L. O'Donohue, David Jacobowitz
OPIOID-INDUCED HYPERMOTILITY IN RATS, Pages 155-158, Edgar T. Iwamoto
DIFFERENCES BETWEEN THE MECHANISM OF ACTION OF MORPHINE ANTINOCICEPTION IN MICE AND RATS, Pages 159-162, Tsu-Ching Fu, Stephen P. Halenda, William L. Dewey
ACTIONS OF OPIOID PEPTIDES ON THE RESPONSIVENESS OF RETICULAR NEURONES TO TOOTH-PULP STIMULATION, Pages 163-166, T.A. Lovick, J.H. Wolstencroft
INHIBITION OF GLUTAMATE INDUCED CORTICAL RELEASE OF ADENINE DERIVATIVES BY OPIATES AND ENKEPHALIN, Pages 167-170, Khem Jhamandas, Anne Dumbrille
INTRASTRIATAL INJECTION OF MORPHINE: EFFECT ON EMG-RECORDED ACTIVITY OF THE GASTROCNEMIUS-SOLEUS MUSCLE OF RATS, Pages 171-174, U. Havemann, M. Winkler, E. Genc, K. Kuschinsky
EEG ALTERATIONS INDUCED IN RATS BY ETHYLKETOCYCLAZOCINE, CYCLAZOCINE, AND MORPHINE: THE DIFFERENTIAL EFFECTS OF NALOXONE, Pages 175-178, Frank C. Tortella, Alan Cowan, Martin W. Adler
ONTOGENESIS OF ENKEPHALINERGIC SYSTEMS IN RAT BRAIN, Pages 179-182, S. de la Baume, G. Patey, C. Gros, J.C. Schwartz
IMMUNOHISTOCHEMICAL LOCALIZATION OF METHIONINE ENKEPHALIN IN OLD WORLD PRIMATES: PRELIMINARY OBSERVATIONS, Pages 183-186, Suzanne Haber, Robert Elde
ENDORPHIN AND CORTICOTROPIN REGULATE THE ACTIVITY OF SEPTAL-HIPPOCAMPAL CHOLINERGIC NEURONS, Pages 187-189, L.J. Botticelli, R.J. Wurtman
NALOXONE EXCITATION OF SPINAL DORSAL HORN UNITS SHOWS DIURNAL VARIATION, Pages 191-194, James L. Henry
PARTIAL PURIFICATION OF ENDORPHINS FROM HUMAN CEREBROSPINAL FLUID FROM CHRONIC BACK PAIN AND ELECTIVE SURGERY PATIENTS, Pages 197-200, Barney E. Miller, Ellen E. Codd, Alberte L. Ungar, William L. Byrne, Kit S. Mays, William C. North
IDENTIFICATION OF A NEW OPIOID PEPTIDE FROM THE BOVINE BRAIN AND ITS MECHANISM OF ACTION, Pages 201-204, Hiroshi Takagi, Masamichi Satoh, Hirohito Shiomi, Akinori Akaike, Hiroshi Ueda, Shin-ichi Kawajiri, Masaki Yamamoto, Hiro Amano
ACUPUNCTURE TOLERANCE IN RATS: ANTI-OPIATE SUBSTRATES IMPLICATED, Pages 205-208, C.S. Han, J. Tang, B.S. Huang, X.N. Liang, N.H. Zhang
STUDIES ON POSSIBLE PRECURSORS FOR THE ENKEPHALINS, Pages 209-212, Ann Beaumont, Anne Dell, John Hughes, Bernard Malfroy, Howard R. Morris
ENKEPHALIN PRECURSORS FROM GUINEA-PIG MYENTERIC PLEXUS, Pages 213-216, A.T. McKnight, R.P. Sosa, A.D. Corbett, H.W. Kosterlitz
CHARACTERIZATION OF HIGH MOLECULAR WEIGHT ENKEPHALIN IMMUNOREACTIVITY IN RAT BRAIN AND BOVINE ADRENAL MEDULLA, Pages 217-220, Steven R. Childers, Solomon H. Snyder
TENTATIVE SUBUNIT COMPOSITION OF ENKEPHALIN-MACROMOLECULE COMPLEXES, Pages 221-224, R. Suzanne Zukin, Gail D. Federoff, Richard M. Kream
CHARACTERIZATION OF A HIGH AFFINITY 3H-βh-ENDORPHIN RECEPTOR IN RAT BRAIN CRUDE SYNAPTOSOMAL FRACTION, Pages 225-228, P.Y. Law, H.H. Loh, R.A. Houghten, Choh Hao Li
ENDORPHIN-REGULATED PROTEIN PHOSPHORYLATION AS A FUNCTIONAL ENTITY OF THE OPIATE-RECEPTOR COMPLEX, Pages 229-232, Y.H. Ehrlich, L.G. Davis, P. Keen, E.G. Brunngraber
β-CASOMORPHINS–NOVEL OPIOID PEPTIDES DERIVED FROM BOVINE CASEIN–ISOLATION AND STRUCTURE, Pages 233-236, A. Henschen, V. Brantl, H. Teschemacher, F. Lottspeich
THE EFFECT OF OPIOIDS ON THE PHOSPHORYLATION ‘IN VITRO’ OF SYNAPTIC MEMBRANE PROTEINS, Pages 239-242, Doris H. Clouet, Norman Williams
β-LIPOTROPIN, CORTICOTROPIN AND β-ENDORPHIN: PHOSPHORYLATION BY CYCLIC AMP-DEPENDENT AND INDEPENDENT PROTEIN KINASES, Pages 243-246, Joachim D. Raese, Michael R. Boarder, George Makk, Jack D. Barchas
PHOSPHORYLATION OF ENDOGENOUS β-LIPOTROPIN AND OTHER PEPTIDES BY SLICES OF PITUITARY, ADULT BRAIN AND NEONATE BRAIN OF THE RAT, Pages 247-250, Michael R. Boarder, Joachim D. Raese, Jack D. Barchas
THE ROLE OF Na+ AND GTP IN NG108-15 OPIATE RECEPTOR FUNCTION, Pages 251-254, Arthur J. Blume, David Lichtshtein, Gloria Boone
GROWTH INHIBITION INDUCED BY METHADONE: PREVENTION BY DIBUTYRYL CYCLIC ADENOSINE MONOPHOSPHATE, Pages 255-258, Alfred A. Smith, Nabila Wassef
CALCIUM IONS AND OPIOID ACTION IN NEUROBLASTOMA X GLIOMA HYBRID CELLS, Pages 259-262, M. Brandt, C. Buchen, B. Hamprecht
CALCIUM ANTAGONISM OF OPIATE ACTION IN THE NON-TOLERANT AND TOLERANT GUINEA PIG ILEUM, Pages 263-266, Jean Hu, J. Pablo Huidobro-Toro, E. Leong Way
OPIOID-INDUCED CHANGES IN CELL SURFACE COMPOSITION OF NEUROTUMOR CELL LINES, Pages 267-270, Richard J. Miller, Glyn Dawson, Ronald MacLawhon
A ROLE OF LIPID IN OPIATE-RECEPTOR INTERACTION, Pages 271-274, Shunji Nagaoka, Junichi Hasegawa, Masakatsu Nozaki, Keita Kamikubo, Masaru Sogami, Hajime Fujimura, Eiji Imai, Mikio Hori
POTENTIATION OF OPIATE EFFECTS IN THE NEUROBLASTOMA CELL LINE N18TG-2 BY SULFATIDE INCORPORATION, Pages 275-278, T.D. Nicksic, P.Y. Law, H.H. Loh, A. Herz
SEARCH FOR A “SODIUM EFFECT” IN THE ACTION OF OPIATES ON HUMAN PLASMA CHOLINESTERASE, Pages 279-282, Alexander Gero
RELEASE OF ENDORPHINS AND THEIR MODULATION FROM RAT BRAIN IN VITRO, Pages 285-288, Hillman Osborne, Ryszard Przewiocki, Volker Höllt, Albert Herz
IN VITRO BIOSYNTHESIS AND CHEMICAL CHARACTERIZATION OF ACTH AND ACTH FRAGMENTS BY THE RAT PARS INTERMEDIA, Pages 289-292, C. Gianoulakis, N.G. Seidah, R. Routhier, M. Chrétien
MATURATION OF THE COMMON PRECURSOR FOR BETA-ENDORPHIN AND ALPHA-MSH IN THE RAT PARS INTERMEDIA, Pages 293-296, F. Gossard, P. Crine, N.G. Seidah, M. Chrétien
PAIN THRESHOLD AND BRAIN ENDORPHIN LEVELS IN GENETICALLY OBESE (ob/ob) AND OPIATE RECEPTOR DEFICIENT (CXBK) MICE, Pages 297-300, B.P. Roy, R. Cheng, J. Phelan, B.H. Pomeranz
SPECIFIC PROCESSING OF ENDORPHINS IN RAT BRAIN, Pages 301-306, Siraik Zakarian, Derek G. Smyth
PLASMA LEVELS OF β-ENDORPHIN/β-LIPOTROPIN IN HUMANS UNDER STRESS, Pages 307-308, Hansjörg Teschemâher, Thomas Breidenbach, Anne König, Marion Luckhardt, Susanne Davies-Osterkamp
THE OCCURRENCE OF β-ENDORPHIN AND OF ALPHA-MELANOTROPIN IN THE SECRETORY GRANULES OF ANTERIOR PITUITARY CORTICOTROPIN/ENDORPHIN CELLS MAY BE COUPLED, Pages 309-312, Eckard Weber, Karl H. Voigt
CORTICOTROPIN, β-LIPOTROPIN/β-ENDORPHIN AND THE NON-CORTICOTROPIN/β-LIPOTROPIN PORTION OF THEIR COMMON PRECURSOR ARE PRESENT IN THE SAME SECRETORY GRANULES, Pages 313-316, Karl H. Voigt, Eckard Weber
HUMORAL ENDORPHIN: ENDOGENOUS OPIATE IN BLOOD CEREBROSPINAL FLUID AND BRAIN, Pages 317-320, Y. Same, Y. Gothilf, B.A. Weissman
DEMONSTRATION OF PLACENTAL ENDORPHINS BY RADIOIMMUNOASSAY AND RADIORECEPTOR TECHNIQUES, Pages 321-324, N.W. Pedigo, H.I. Yamamura, J.C. Houck, C. Chang, C.D. Kimball
INCREASED BIOSYNTHESIS OF β-ENDORPHIN IN THE PARS INTERMEDIA OF RAT PITUITARIES AFTER LONG-TERM TREATMENT WITH HALOPERIDOL, Pages 325-328, Volker Höllt, Ryszard Przewiocki, Michael Bergmann, Ingeborg Haarmann, Theodora Duka
BIOSYNTHESIS OF BETA-ENDORPHIN AND ALPHA-MSH IN THE PARS INTERMEDIA OF RAT PITUITARIES, Pages 329-332, P. Crine, F. Gossard, N.G. Seidah, M. Lis, M. Chrétien
ENDORPHIN LEVELS IN THE RAT BRAIN AFTER THE TOOTH PULP STIMULATION, Pages 333-336, R. Inoki, K. Iwatsubo, T. Kudo, N. Yonehara, M. Oka, Y. Kotani, Y. Kondo, K. Iga
IN VITRO EVIDENCE FOR AN INVOLVEMENT OF INTESTINAL ENDORPHINS IN THE CONTROL OF PERISTALSIS IN THE GUINEA PIG ILEUM. COMPARISON TO RABBIT, RAT, CAT AND DOG SMALL INTESTINE, Pages 337-340, W. Kromer, W. Pretzlaff, E. Scheiblhuber
Using HPLC and fluorometric methods in studying endogenous peptides, Pages 341-344, J. Wideman
CHARACTERIZATION OF ENKEPHALINASES, Pages 345-348, C. Gorenstein, S.H. Snyder
FURTHER CHARACTERISATION AND KINETICS OF APPEARANCE OF HYDROLYSIS PRODUCTS OF MET-ENKEPHALIN, Pages 349-352, Anne Guyon, Bernard P. Roques, Francois Guyon, Alain Foucault, Rémy Perdrisot, Jean-Paul Swerts, Jean-Charles Schwartz
DEGRADATION OF ENKEPHALIN BY TWO BRAIN ENZYMATIC ACTIVITIES, Pages 353-356, Zvi Vogel, Miriam Altstein
ENKEPHALINASE: PRELIMINARY CHARACTERIZATION AND COMPARISON WITH ANGIOTENSIN CONVERTING ENZYME, Pages 357-360, Sue Sullivan, Huda Akil, Deborah Blacker, Jack D. Barchas
ANTAGONISM OF MORPHINE ACTION BY CEREBROSIDE SULFATE ANTIBODY, Pages 363-366, Frederick Craves, Bernard Zalc, Leonid Leybin, Nicole Baumann, Horace Loh
ONE WAY CROSS TOLERANCE FROM MORPHINE TO NANTRADOL - A POTENT, NON-OPIOID ANALGETIC, Pages 367-370, G.M. Milne, H.M. McIlhenny, M.R. Johnson, B.K. Koe, A. Weissman
ORAL TRYPTOPHAN AS A POTENTIAL ADJUNCTIVE THERAPY IN CHRONIC PAIN PATIENTS, Pages 371-374, M.A. Noel, W.L. Byrne, K.S. Mays
DIETARY SUPPLEMENTATION WITH L-TRYPTOPHAN REVERSES TOLERANCE TO ANALGESIA INDUCED BY PERIAQUEDUCTAL GRAY STIMULATION IN HUMANS, Pages 375-378, Yoshio Hosobuchi
FURTHER STUDIES ON THE ANALGESIC ACTIVITY OF D-PHENYLALANINE (DPA) IN MICE AND HUMANS, Pages 379-382, S. Ehrenpreis, R.C. Balagot, S. Myles, C. Advocate, J.E. Comaty
THE ANTIPEPTIDASES INCREASE ELECTROACUPUNCTURE ANALGESIA AND SHOW PREDICTABLE HYPALGESIC EFFECTS ON MICE WITH CONGENITALLY ABNORMAL ENDORPHIN SYSTEMS, Pages 383-386, Richard Cheng, Bruce Pomeranz
BIPHASIC DOSE RESPONSE TO BUPRENORPHINE IN THE RAT TAIL FLICK ASSAY: EFFECT OF NALOXONE PRETREATMENT, Pages 387-390, Michael J. Ranee, John A.H. Lord, Trevor Robinson
IS ß-ENDORPHIN INVOLVED IN THE ANALGESIA GENERATED BY STRESS?, Pages 391-394, Ryszard Przewiocki, Mark J. Millan, Albert Herz
CENTRAL 5-HYDROXYTRYPTAMINE, OPIATE-LIKE SUBSTANCES AND ACUPUNCTURE ANALGESIA, Pages 395-398, C.S. Han, J. Tang, S.G. Fan, M.F. Jen, Z.F. Zhou, W.Q. Zhan, X.N. Liang
ULTRAVIOLET RADIATION-INDUCED NOCICEPTION: BASIS FOR A NOVEL ANALGESIC TEST IN MICE, Pages 399-402, F. Porreca, M.W. Adler, A. Cowan, R.J. Tallarida
ESTROGEN TREATMENT ALTERS NARCOTIC DISPOSITION IN THE RAT, Pages 405-407, Mary Jeanne Kreek, Laura T. Brown, Wendy J. Bernstein, Edith H. Harte
EFFECTS OF MORPHINE ON SERUM PROLACTIN LEVELS AND DOPAMINE TURNOVER IN THE MEDIAN EMINENCE: ACUTE AND CHRONIC EFFECTS, Pages 409-412, Scott N. Deyo, Robert M. Swift, Richard J. Miller
THE EFFECT OF ACUTE ADMINISTRATION OF MORPHINE AND OPIATE ANTAGONISTS ON THE INDOLE CONTENT OF THE RAT PINEAL GLAND, Pages 413-416, Robert M. Levy, Ivan N. Mefford, Stanley Watson, Huda Akil, Jack D. Barchas
CHANGES INDUCED BY AN OPIOID ON BLOOD GLUCOSE AND INSULIN IN THE RAT, Pages 417-420, S. Spampinato, S. Ferri, G. Costa
NARCOTIC ANTAGONISTS INCREASE SERUM LUTEINIZING HORMONE LEVELS BY A NONTESTOSTERONE-DEPENDENT MECHANISM, Pages 421-424, Theodore J. Cicero, Roy D. Bell, Edward R. Meyer, Carol E. Wilcox
NALOXONE'S EFFECTS ON A VARIETY OF MOTIVATED BEHAVIORS, Pages 427-430, Larry D. Reid, June M. Stapleton, Nancy L. Ostrowski, Ralph G. Noble
THE ACTIVATION OF ENDORPHIN(S) BY REWARD, Pages 431-434, Jane E. Dum, Albert Herz
DISCRIMINATION OF THE INTEROCEPTIVE STIMULI PRODUCED BY PHENYL-QUINONE. A MEASURE OF THE AFFECTIVE COMPONENT OF PAIN IN THE RAT, Pages 435-438, Stephen Miksic, Gary Shearman, Harbans Lal
GENERALIZATION STUDY WITH SOME NARCOTIC AND NONNARCOTIC PSYCHOACTIVE DRUGS IN RATS TRAINED TO DISCRIMINATE BETWEEN CYCLAZOCINE AND SALINE, Pages 439-442, Michael D. Mc Carten, Harbans La
DISCRIMINATIVE AND REINFORCING EFFECTS OF SOME SYSTEMICALLY ACTIVE ENKEPHALIN ANALOGUES, Pages 443-446, J.H. Woods, D.W. Hein, S. Herling, A.M. Young, R.J. Valentino
NALOXONE ANTAGONISM OF MORPHINE-WITHDRAWAL BODY SHAKES BY AN AUDITORY CONDITIONAL STIMULUS, Pages 447-450, Harbans Lal, Robert Numan, Nelson Smith
POSSIBLE GABA INVOLVEMENT IN THE MEDIATION OF NARCOTIC ANTAGONIST-INDUCED AVERSIONS, Pages 451-454, C.W.T. Pilcher, Sarah M. Jones, I.P. Stolerman
ENDOGENOUS OPIATES AS MEDIATORS of ACTIVATION AND COPING, Pages 455-458, R.J. Katz, K.A. Roth, K. Schmaltz
SIMILARITY BETWEEN BEHAVIORAL EFFECTS OF DES-TYROSINE-γ-ENDORPHIN AND HALOPERIDOL AND OF α-ENDORPHIN AND AMPHETAMINE, Pages 459-462, Jan M. van Ree, Bela Bohus, David de Wied
DIURNAL DIFFERENCES IN ENKEPHALIN LEVELS CORRELATED WITH NOCICEPTIVE SENSITIVITY, Pages 463-466, David L. Wesche, Robert C.A. Frederickson
ENDORPHIN-LIKE RESPONSES PROVOKED BY INTRACEREBROVENTRICULAR PEPTIDASE INHIBITORS IN MILDLY STRESSED RATS, Pages 467-470, Carl Pinsky, Ashok K. Dua, Egon Brockhausen, Viktor Havlicek, Frank S. LaBella
ACTIONS OF HYPERALGESIC SUBSTANCES {(-)NALOXONE, THEOPHYLLINE AND 5-METHOXY-N,N- DIMETHYLTRYPTAMINE} ON NOCICEPTIVE LEARNING, Pages 471-474, K. RAMABADRAN, J.C. GUILLON, J. JACOB
THE EFFECT OF PROTOTYPE OPIATE RECEPTOR AGONISTS AND OPIOID PEPTIDES ON BODY TEMPERATURE AND BEHAVIOUR AFTER CENTRAL ADMINISTRATION TO CATS, Pages 475-478, Alan Cowan, Peter W. Dettmar, Geoff Metcalf
NALOXONE IMPROVEMENT OF SHOCK PATHOPHYSIOLOGY: EVIDENCE FOR OPIATE RECEPTOR INVOLVEMENT, Pages 479-482, John W. Holaday, Alan I. Faden
NALOXONE REVERSAL OF HYPOTENSION CAUSED BY SPINAL TRANSECTION, Pages 483-486, Alan I. Faden, John W. Holaday
ELECTROCONVULSIVE SHOCK (ECS) IN RATS: NALOXONE MODIFICATION OF POST-ECS BEHAVIORS PROVIDES EVIDENCE FOR FUNCTIONAL ENDORPHIN RELEASE, Pages 487-490, Gregory Lucas Belenky, John W. Holaday
EVIDENCE FOR BIOCHEMICAL ADAPTATION IN MORPHINE TOLERANCE DEPENDENCE, Pages 493-496, Vivian Y.H. Hook, K. Bradley Stokes, Nancy M. Lee
Serotonin-Substance-P Pathway in the Manifestation of Gut Withdrawal, Pages 497-500, Alan R. Gintzler
DEVELOPMENT OF TOLERANCE TO AND DEPENDENCE ON OPIOIDS IN THE ISOLATED LONGITUDINAL MUSCLE STRIPS OF GUINEA PIG ILEUM, Pages 501-504, Hiroshi Kaneto, Joe Watanabe, Yoshiaki Kohno
LACK OF DEPENDENCE LIABILITY OF DEZOCINE (WY-16225) IN THE MYENTERIC PLEXUS-LONGITUDINAL MUSCLE STRIP OF GUINEA PIG ILEUM, Pages 505-508, R. Greenberg, R. Ippersiel
TOLERANCE, DEPENDENCE AND QUASI-DEPENDENCE IN THE GUINEA-PIG ISOLATED ILEUM, Pages 509-512, Harry O.J. Collier, Nigel J. Cuthbert, David L. Francis
INTERACTIONS BETWEEN CLONIDINE AND A WITHDRAWAL-INDUCING BENZAZOCINE UPON THE ISOLATED MOUSE VAS DEFERENS AND GUINEA-PIG ILEUM, Pages 513-516, Charles B. Smith, Rita J. Valentino
AN EXAMINATION OF TOLERANCE TO THE ANTINOCICEPTIVE EFFECTS OF MORPHINE, CLONIDINE AND THEIR COMBINATION IN THE MOUSE TAIL IMMERSION TEST, Pages 517-520, Jonathan J. Lipman, P.S.J. Spencer
DIFFERENTIAL EFFECTS OF LEU- AND MET-ENKEPHALIN ON NARCOTIC-INDUCED ENHANCEMENT OF NALOXONE EFFICACY, Pages 521-524, A.E. TAKEMORI, JEFFRY L. VAUGHT, TAKAFUMI KITANO
EXAGGERATED WEIGHT LOSS IN GENETICALLY OBESE (ob/ob) MICE BY WITHDRAWAL FROM MORPHINE, Pages 525-528, James J. Flynn, Joseph Walker, David L. Margules
N-DEALKYLATION IN THE CNS: EFFECT OF TOLERANCE AND OPIATE ANTAGONISTS, Pages 529-532, Elliot F. Hahn, Baiba I. Norton, Jack Fishman
ELECTROACUPUNCTURE HYPALGESIA IS ENHANCED IN MORPHINE DEPENDENT MICE; SHOWING NO CROSS-TOLERANCE AND REDUCING SIGNS OF WITHDRAWAL, Pages 533-535, Richard Cheng, Bruce Pomeranz, George Yu
STUDY OF CROSS-TOLERANCE TO THE EFFECTS OF MORPHINE AND METHADONE ON THE EEG AND BEHAVIOR OF THE L-ALPHA-ACETYLMETHADOL (LAAM)-MAINTAINED RAT, Pages 537-539, J. Edward Moreton, Scott E. Lukas, Naim Khazan
DEVELOPMENT OF TOLERANCE TO OPIATES IN EXPLANTS OF MOUSE SPINAL CORD WITH ATTACHED DORSAL ROOT GANGLIA, Pages 541-544, Stanley M. Crain, Bea Crain, Tara Finnigan, Eric J. Simon
THE EFFECTS OF MELANOCYTE-STIMULATING HORMONE RELEASE INHIBITING FACTOR AND SYNTHETIC ANALOGS ON TOLERANCE TO AND PHYSICAL DEPENDENCE ON MORPHINE, Pages 545-548, Hemendra N. Bhargava, Ronald F. Ritzmann, Roderich Walter
MODIFICATION OF DEVELOPMENT OF PHYSICAL DEPENDENCE ON MORPHINE BY THYROTROPIN-RELEASING HORMONE, Pages 549-552, Hemendra N. Bhargava
INHIBITION OF TOLERANCE TO MORPHINE BY {DPhe7}-ACTH(1-10)-NH2, Pages 553-556, R.E. Chipkin, J.M. Stewart, K. Channabasavaiah, M.L. Gay, W.A. Krivoy
DEPENDENCE IN NON-ADDICT HUMANS AFTER A SINGLE DOSE OF MORPHINE, Pages 557-560, Reese T. Jones
OPIATES AND SOCIAL DEPENDENCE, Pages 561-564, Jaak Panksepp
REVERSAL OF CLONIDINE-INDUCED HYPOTENSION BY OPIOID ANTAGONISTS IN MAN, Pages 565-566, R.B. Resnick, A.M. Washton, H. Lai
Author Index, Pages 567-570