Electrospun Nanofibers Research: Recent Developments

ELECTROSPUN NANOFIBERS RESEARCH: RECENT DEVELOPMENTS......Page 3
CONTENTS......Page 7
PREFACE......Page 9
ABSTRACT......Page 15
1.1. Electrospinning Overview......Page 16
1.2. Electrospinning Production for Tissue Engineering......Page 18
2. APPLICATIONS OF ELECTROSPUN NANOFIBERS IN BIOMEDICAL APPLICATIONS......Page 23
3.1. Historical and Definition......Page 24
3.2. Musculoskeletal Tissue Engineering......Page 25
3.3. Skin Tissue Engineering......Page 26
3.5. Cardiac Tissue Engineering......Page 27
3.6. Neural Tissue Engineering......Page 28
6. REFERENCES......Page 29
ABSTRACT......Page 33
1. INTRODUCTION......Page 34
2. POLYMER PHYSICAL-CHEMICAL PROPERTIES......Page 35
3. CONTROL OF ENVIRONMENTAL CONDITIONS......Page 37
4. SCAFFOLD WETTING......Page 40
5. SCAFFOLD STERILIZATION......Page 41
6. SCAFFOLD SHRINKAGE......Page 42
7. Handling of scaffolds for cell culture......Page 44
8. CONCLUSION......Page 45
REFERENCES......Page 46
ABSTRACT......Page 49
INTRODUCTION......Page 50
Simulation of Electrospun Web......Page 51
Manual Method......Page 52
Distance Transform......Page 53
Direct Tracking......Page 54
REAL WEBS TREATMENT......Page 56
RESULTS AND DISCUSSION......Page 57
CONCLUSION......Page 70
REFERENCES......Page 71
INTRODUCTION......Page 73
Sample Preparation......Page 75
Characterization......Page 76
EFFECT OF PANI CONTENT......Page 77
EFFECT OF ELECTROSPINNING TEMPERATURE......Page 79
EFFECT OF APPLIED VOLTAGE......Page 81
CONCLUSIONS......Page 84
REFERENCES......Page 85
1. INTRODUCTION......Page 87
2.1. Applied Voltage......Page 88
3. THEORY AND MODELING......Page 89
4. EFFECT OF VOLTAGE AND SPINNING DISTANCE ON MORPHOLOGY AND DIAMETER......Page 91
REFERENCES......Page 93
1. INTRODUCTION......Page 95
2.1. Solution Properties......Page 99
2.1.4. Surface Tension......Page 100
2.1.5. Solution Conductivity......Page 102
2.2.2. Feed Rate......Page 103
3. CONCLUDING REMARKS......Page 105
REFERENCES......Page 106
ABSTRACT......Page 107
INTRODUCTION......Page 108
SIEVING METHODS......Page 110
MERCURY POROSIMETRY......Page 111
IMAGE ANALYSIS......Page 112
REAL WEBS......Page 113
Simulated Webs:......Page 114
EXPERIMENTAL:......Page 115
RESULTS AND DISCUSSION:......Page 117
REFERENCES......Page 127
INTRODUCTION......Page 129
Manual Method......Page 131
Distance Transform Method......Page 132
New Distance Transform Method......Page 135
THRESHOLDING......Page 140
EXPERIMENTAL......Page 142
RESULTS AND DISCUSSION......Page 144
REFERENCES......Page 152
ABSTRACT......Page 155
INTRODUCTION......Page 156
Solution Preparation and Electrospinning......Page 159
CHOICE OF PARAMETERS AND RANGE......Page 160
EXPERIMENTAL DESIGN......Page 161
RESPONSE SURFACE METHODOLOGY......Page 162
RESULTS AND DISCUSSION......Page 164
Spinning Distance......Page 169
Applied Voltage......Page 170
Volume Flow Rate......Page 171
Spinning Distance......Page 173
Volume Flow Rate......Page 174
CONCLUSION......Page 176
APPENDIX......Page 177
REFERENCES......Page 181
ABSTRACT......Page 185
INTRODUCTION......Page 186
ELECTROSPINNING SET UP......Page 187
Solution Concentration......Page 188
Surface Tension......Page 189
Solution Conductivity......Page 190
Solution Conductivity......Page 191
Effect of Salt Addition......Page 192
Solvent......Page 193
Applied Voltage......Page 194
Feed Rate......Page 196
Distance of Needle Tip to the Collector......Page 198
THEORY AND MODELING......Page 199
Natural fibers......Page 202
ELECTROSPINNING OF SILK FIBERS INTRODUCTION......Page 203
CRYSTAL STRUCTURE OF SILK (FIBROIN) IN VARIOUS STAGES OF ELECTROSPINNING......Page 204
THE Β STRUCTURE OF SILK......Page 205
Fibroin Dissolution......Page 206
Effect of Silk Polymer Concentration on Fiber Diameter......Page 207
Effect of Voltage and of the Spinning Distance on Morphology and Diameter......Page 209
CHARACTERIZATION......Page 213
ELECTROSPINNING OF CELLULOSE AND OF CELLULOSE ACETATE......Page 214
ELECTROSPINNING OF A CTA SOLUTION......Page 215
REFERENCES......Page 216
1. INTRODUCTION......Page 221
2.4. Characterization......Page 223
3. RESULTS AND DISCUSSION......Page 224
4. CONCLUSION......Page 226
REFERENCES......Page 228
ABSTRACT......Page 229
1. INTRODUCTION......Page 230
2.4. Gelatin Films......Page 231
3.1. Gelatin Solution Stability......Page 232
3.2. Gelatin Nanofiber Morphology......Page 235
3.3. Structural Characterization by FTIR, DSC and XRD......Page 237
4. CONCLUSIONS......Page 240
REFERENCES......Page 241
ABSTRACT......Page 243
1. INTRODUCTION......Page 244
2.3. Crosslinking with Glutaraldehyde......Page 245
3. RESULTS AND DISCUSSIONS......Page 246
3.3. Structural Characterization by FTIR and XRD......Page 249
REFERENCES......Page 251
ABSTRACT......Page 253
2.1. Materials......Page 254
2.3. Structural Characterization......Page 255
3.1. Chitin Depolymerisation by Ultrasonic Treatment......Page 256
3.2. Chitin Depolymerisation by Microwave Treatment......Page 258
REFERENCES......Page 265
ABSTRACT......Page 267
1. INTRODUCTION......Page 268
2. ELECTROSPINNING......Page 269
3. NANOFIBERS IN TISSUE ENGINEERING......Page 271
3.1. WOUND DRESSING AND SKIN TISSUE ENGINEERING......Page 272
3.2. BONE TISSUE ENGINEERING......Page 273
3.3. ARTIFICIAL BLOOD VESSEL ENGINEERING......Page 276
3.4. NEURAL TISSUE ENGINEERING......Page 279
4. STEM CELLS AND NANOFIBERS......Page 281
REFERENCES......Page 284
1. INTRODUCTION......Page 293
2.3. Electrospinning......Page 295
4.1. Effect of Silk Concentration......Page 296
4.3. Effect of Electrospinning Temperature......Page 302
5. EXPERIMENTAL DESIGN......Page 304
CONCLUSION......Page 307
REFERENCES......Page 308
INDEX......Page 311