Effects of Low Dose and Low Dose Rate Radiation

Content: 
Inside Front Cover
Page ii

Front Matter
Page iii

Copyright page
Page iv

Preface
Page xi
JOHN T. LETT

Introduction and Overview
Pages 1-6
ODDVAR F. NYGAARD, WARREN K. SINCLAIR

Track Structure Considerations in Low Dose and Low Dose Rate Effects of Ionizing Radiation
Pages 7-44
DUDLEY T. GOODHEAD

Dose—Time—Response Models for Radiation Carcinogenesis
Pages 45-76
STANLEY B. CURTIS, DUNCAN C. THOMAS

Radiation-Induced Mutation in Mammalian Cells at Low Doses and Dose Rates
Pages 77-124
JOHN THACKER

Commentary to Thacker: A Consideration of the Mechanisms of Induction of Mutations in Mammalian Cells by Low Doses and Dose Rates of Ionizing Radiation
Pages 125-135
R. JULIAN PRESTON

Oncogenic Cell Transformation in Vitro
Pages 137-158
ROGER COX, JOHN B. LITTLE

Commentary 1 to Cox and Little: The Unbridged Gap between in Vivo and in Vitro Models for Evaluation of Low Dose, Low Dose Rate Radiation-Induced Oncogenic Transformation
Pages 159-165
M. TERZAGHI-HOWE

Commentary 2 to Cox and Little: Radiation-Induced Oncogenic Transformation: The Interplay between Dose, Dose Protraction, and Radiation Quality
Pages 167-179
DAVID J. BRENNER, ERIC J. HALL

The Role of Animal Experiments in Estimates of Radiation Risk
Pages 181-197
R.J.M. FRY

Commentary to Fry: Radiation Carcinogenesis Studies in Animals– Advantages, Limitations, and Caveats
Pages 199-213
J.J. BROERSE, D.W. VAN BEKKUM

Radiation Carcinogenesis in Humans
Pages 215-258
WILLIAM J. SCHULL, KENNETH M. WEISS

Commentary 1 to Schull and Weiss: Low Dose Extrapolation, Time Following Exposure, and Transport between Populations
Pages 259-272
CHARLES E. LAND

Commentary 2 to Schull and Weiss: Human Cellular Radiosensitivity—The Search for the Diagnostic Holy Grail or a Poisoned Chalice
Pages 273-292
C.F. ARLETT

Commentary 3 to Schull and Weiss: Increased Definition of Abnormal Radiosensitivity Using Low Dose Rate Testing
Pages 293-302
NORMAN E. GENTNER

Radiation Protection: Recent Recommendations of the ICRP and the NCRP and Their Biological Basis
Pages 303-324
WARREN K. SINCLAIR

Index
Pages 325-336