Dupuytren Disease and Related Diseases - The Cutting Edge

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Treatment of Dupuytren Disease in Different Countries: A Welcome Address from the President of IFSSH....Pages 3-9
The Epidemiology of Surgical Intervention for Dupuytren Contracture in England....Pages 11-15
Favorite Options of German Hand Surgeons in the Treatment of Dupuytren Disease....Pages 17-21
Trends in Dupuytren Treatment in the United States....Pages 23-27
International Patient Survey (Part 1: Dupuytren Disease)....Pages 29-40
Front Matter....Pages 41-41
The Extracellular Matrix in Dupuytren Disease....Pages 43-54
Biomarkers of Postsurgical Outcome in Dupuytren Disease....Pages 55-61
Tumour Necrosis Factor as a Therapeutic Target in Dupuytren Disease....Pages 63-71
Contraction Versus Contracture: Considerations on the Pathogenesis of Dupuytren Disease....Pages 73-81
Controversy: The Contracture in Dupuytren Disease Is an Active Process....Pages 83-87
Controversy: The Contracture in Dupuytren Disease Is a Passive Process....Pages 89-96
Front Matter....Pages 97-97
Human Genetic Studies of Dupuytren Disease: A Primer....Pages 99-103
Network Analysis and Fine-Mapping GWAS Loci to Identify Genes and Functional Variants Involved in the Development of Dupuytren Disease....Pages 105-111
Front Matter....Pages 113-113
Collagenase Injection: Journey from Bench to Current Advanced Clinical Use....Pages 115-125
Efficacy of Using Local Anesthesia Before Collagenase Injection in Reducing Overall Pain Experience in Patients Treated for Dupuytren Contracture: A Quasi-Randomized Study....Pages 127-129
Effect of Delayed Finger Extension on the Efficacy and Safety of Collagenase Clostridium Histolyticum Treatment for Dupuytren Contracture....Pages 131-136
The Use of Dynamic Dorsal Splint for Dupuytren Rehabilitation After Collagenase Injection....Pages 137-140
Prospective Multicenter, Multinational Study to Evaluate the Safety and Efficacy of Concurrent Collagenase Clostridium Histolyticum Injections to Treat Two Dupuytren Contractures in the Same Hand....Pages 141-144
Collagenase: What We May Never Know (A Discussion)....Pages 145-149
Controversy: Comparison of the Literature on PNF and CCH as Minimally Invasive Treatment Options for Dupuytren Disease....Pages 151-157
Front Matter....Pages 159-159
Tips and Pearls for PNF and Collagenase: A Ten-Year Personal Experience....Pages 161-170
Clinical Results of Percutaneous Needle Fasciotomy for Dupuytren Contracture: Are There Significant Correlations Between Preoperative Dupuytren Diathesis Score and Contracture Recurrence?....Pages 171-177
Effectiveness of Percutaneous Needle Fasciotomy for Second or Higher Recurrence in Dupuytren Contracture....Pages 179-184
Controversy: How to Treat Severe PIP Contractures? - Collagenase Treatment....Pages 185-189
Controversy: How to Treat Severe PIP Contractures? - Surgical Correction....Pages 191-195
Front Matter....Pages 197-197
Correlation of Function with Deformity in Dupuytren Disease: The Condition-Specific Southampton Scoring Scheme Outperforms the Generic QuickDASH....Pages 199-203
Tonometry as an Outcome Measure for the Treatment of Early Dupuytren Disease....Pages 205-209
The Intra- and Interobserver Agreement on Diagnosis of Dupuytren Disease, Measurements of Severity of Contracture, and Disease Extent....Pages 211-215
Variation in Range of Movement Reporting in Dupuytren Disease....Pages 217-220
Use of Digital Photography and Mobile Device Application to Assess Finger Deformity in Dupuytren Disease....Pages 221-223
Application for Determining the Degree and Diagnose Code of Dupuytren Contracture by Digital Photography....Pages 225-228
Front Matter....Pages 229-229
Treatment of Dupuytren Disease: Where Are We Now?....Pages 231-239
Steroid Injection and Needle Aponeurotomy for Dupuytren Disease....Pages 241-249
Minimally Invasive Treatment of Dupuytren Contracture: Collagenase Versus PNF....Pages 251-258
Comparative Effectiveness of Collagenase Injection for Dupuytren Contracture....Pages 259-270
Short-Term Cost-Utility Analysis of Collagenase Versus Fasciectomy for Dupuytren Contracture....Pages 271-275
An Easy Way for Clinical Validation of the Pharmacoeconomic Model in Dupuytren Disease....Pages 277-281
Front Matter....Pages 283-283
Preliminary Soft-Tissue Distraction with the Digit WidgetTM in the Management of Advanced Dupuytren Contracture at the Proximal Interphalangeal Joint....Pages 285-290
Is Recurrence After Treatment Predictable? Risk Factors in Dupuytren Disease....Pages 291-297
Is Recurrence of Dupuytren Disease Avoided in Full-Thickness Grafting?....Pages 299-304
Front Matter....Pages 283-283
The Use of Acellular Dermal Matrix in Dupuytren Disease....Pages 305-309
Indications of the Continuous Extension Technique (TEC) for Severe Dupuytren Disease and Recurrences....Pages 311-316
Experience in Treating Patients with Stage IV of Dupuytren Contracture (PNF vs. Fasciectomy)....Pages 317-321
Controversy: Splinting for Dupuytren Contracture....Pages 323-329
Front Matter....Pages 331-331
Introduction to Radiation Biology When Treating Hyperproliferative Benign Diseases....Pages 333-339
Review of Radiation Therapy for Palmar and Plantar Fibromatosis (Dupuytren and Ledderhose Disease)....Pages 341-355
Splinting as a Therapeutic Option in Dupuytren Contractures....Pages 357-361
Treatment Options for Patients with Adhesive Capsulitis (Frozen Shoulder)....Pages 363-369
International Patient Survey (Part 2: Ledderhose Disease)....Pages 371-379
Peyronie Disease....Pages 381-388
Front Matter....Pages 389-389
The Next Stage of Clinical Dupuytren Research: Biomarkers and Chronic Disease Research Tools....Pages 391-407
The Future of Basic Dupuytren Disease Research....Pages 409-411
How Should We Fund Basic Research of Dupuytren Disease?....Pages 413-415
Clinical Research: International Collaboration to Execute High-Powered Clinical Trials....Pages 417-419
Patient-Rated Outcome Measures and Dupuytren Contracture....Pages 421-426
IDDB: An International Research Database of the Dupuytren Foundation....Pages 427-435
International Clinical Research – The Australian Perspective: A Personal View....Pages 437-440
Open Questions and Potential Answers....Pages 441-445
Back Matter....Pages 447-450