Dubois' lupus erythematosus

Content: Historical background of discoid and systemic lupus erythematosus --
The definition and classification of systemic lupus erythematosus --
Environmental aspects of lupus --
The epidemiology of systemic lupus erythematosus --
Overview of pathogenesis of systemic lupus erythematosus --
The genetics of human lupus --
The genetics of murine systemic lupus erythematosus --
Apoptosis --
The interaction of T cells with cells of the innate immune system and B cells in the pathogenesis of SLE --
Cytokines and interferons in lupus --
B cells in systemic lupus erythematosus --
Abnormalities in immune complex clearance and Fcy receptor function --
Complement and systemic lupus erythematosus --
Mechanisms of acute inflammation and vascular injury in systemic lupus erythematosus --
Idiotypes and idiotype networks --
The importance of sex hormones in systemic lupus erythematosus --
Neuroendocrine immune interactions: principles and relevance to systemic lupus erythematosus --
Animal models of systemic lupus erythematosus --
Pathogenesis of atherosclerosis in lupus --
Autoantigens and defects in immune tolerance in lupus --
The structure and derivation of antibodies and autoantibodies --
Antinuclear antibodies: an overview --
Antibodies to DNA --
Antibodies to histones and nucleosome-related antigens --
Antibodies to Ro/SSA and La/SSB --
Antibodies to spliceosomal components --
The lupus anticoagulant and antiphospholipid antibodies --
Other serologic abnormalities in systemic lupus erythematosus --
Pathomechanisms of cutaneous lupus erythematosus --
Lupus-specific skin disease (cutaneous LE) --
Lupus-nonspecific skin disease --
The clinical presentation of systemic lupus erythematosus --
The musculoskeletal system --
Cardiovascular manifestations of lupus --
Pulmonary manifestations of systemic lupus erythematosus. Clinical apsects of vasculitis and selected cutaneovascular manifestations of systemic lupus erythematosus --
The nervous system --
Psychopathology of lupus and neuroimaging --
Sjogren\'s syndrome --
Ocular, aural, and oral manifestations --
Hematologic and lymphoid abnormalities in systemic lupus erythematosus --
Gastrointestinal and hepatic manifestations --
Systemic lupus erythematosus in childhood and adolescence --
Drug-induced lupus --
Infections in systemic lupus erythematosus --
Serum and plasma protein abnormalities and other clinical laboratory determinations in systemic lupus erythematosus --
Clinical indices in the assessment of lupus --
Clinical application of serologic abnormalities in systemic lupus erythematosus --
Differential diagnosis and disease associations --
Mixed connective-tissue disease and overlap syndromes --
The mother in systemic lupus erythematosus --
The fetus in systemic lupus erythematosus --
Neonatal lupus --
Reproductive issues in women with autoimmune disease --
Lupus nephritis: pathology and pathogenesis --
Clinical and laboratory features of lupus nephritis --
Principles of therapy and local measures --
Nonsteroidals and salicylates for systemic lupus erythematosus --
Antimalarial therapies --
Systemic glucocorticoid therapy in systemic lupus erythematosus --
Immunosuppressive drug therapy --
Nonpharmacologic and complementary therapeutic modalities --
Fibromyalgia in SLE and the use of complementary and alternative medicine --
Hormones and gender-related issues --
Clinical and management aspects of the antiphospholipid antibody syndrome --
Additional therapies used in the management of lupus --
Adjunctive measures and issues: allergies, antibiotics, vaccines and disability --
Issues in drug development in SLE: clinical trial design, outcome, measures, and biomarkers --
Prognosis, mortality, and morbidity in systemic lupus erythematosus --
Biologics and stem cell therapies for lupus --
Appendics: A patient\'s guide to lupus erythematosus --
Lupus resource materials --
The medical outcome survey short-form general health survey.