DRUGS:PHOTOCHEMISTRY AND PHOTO

Cover......Page 1
Front Page......Page 3
Preface......Page 7
Contents......Page 9
Photochemistry of Drugs:\rAn Overview and Practical Problems......Page 11
Medicinal Photochemistry\r(An Introduction with Attention to Kinetic Aspects)......Page 84
Photoreactivity of Selected Antimalarial\rCompounds in Solution and in the Solid State......Page 97
Photochemistry of Diuretic Drugs in Solution......Page 110
New Results in the Photoinstability of\rAntimycotics......Page 126
Photoreactivity versus Activity of a Selected Class of\rPhenothiazines: A Comparative Study......Page 144
Photoprocesses in Photosensitising Drugs\rContaining a Benzophenone-like Chromophore......Page 160
Photostability of Coumarin......Page 172
Photostabilities of Several Chemical Compounds\rused as Active Ingredients in Sunscreens......Page 181
An Analytical and Structural Study of the\rPhotostability of some Leukotriene B4 Antagonists......Page 192
Molecular Mechanisms of Photosensitization\rInduced by Drugs on Biological Systems and Design\rof Photoprotective Systems......Page 204
A Comparison between the Photochemical and\rPhotosensitising Properties of Different Drugs......Page 221
Photostability of Drug Substances and Drug\rProducts: A Validated Reference Method for\rImplementing the ICH Photostability Study\rGuidelines......Page 237
The Elaboration and Application of the ICH\rGuideline on Photostability :\rA European View......Page 253
Selecting the Right Source for Pharmaceutical\rPhotostability Testing......Page 257
Design and Validation Characteristics of\rEnvironmental Chambers for Photostability\rTesting......Page 282
Design Limits and Qualification Issues for\rRoom-size Solar Simulators in a GLP Environment......Page 298
Actinometry : Concepts and Experiments......Page 305
trans-2-Nitrocinnamaldehyde as Chemical\rActinometer for the UV=A Range in Photostability\rTesting of Pharmaceuticals......Page 315
Subject Index......Page 327
Back Cover......Page 337