Drugs and Transport Processes: A Symposium

Front Matter....Pages i-xii
Front Matter....Pages 1-1
The effects of drugs on the electrophysiological properties of kidney tubules....Pages 3-22
Receptors for mercurial and ethacrynic acid inhibition of sodium chloride transport....Pages 23-39
Interaction of diuretics with thiols and cell membranes in kidney tubules....Pages 41-51
The location and chemical nature of drug ‘targets’ within the human erythrocyte membrane....Pages 53-72
The relation between renal acidification and bicarbonate reabsorption. A view of CO2-mediated secretion in renal and other epithelia....Pages 73-97
Front Matter....Pages 99-99
Thyroid and Sodium Transport....Pages 101-110
Adrenergic receptors in epithelia....Pages 111-127
Some aspects of steroidal action on the isolated frog skin....Pages 129-148
Current concepts of the mechanism of anion permeability....Pages 149-171
Characteristics of sodium channels in transporting epithelia....Pages 173-189
Front Matter....Pages 191-191
Pore or carrier? Gramicidin A as a simple pore....Pages 193-210
Molecular structures of ionophores and their complexes with metal cations....Pages 211-225
The use of lipid bilayers as cell membrane models: an experimental test using the ionophore, valinomycin....Pages 227-240
Aqueous pores created in thin lipid membranes by the antibiotics nystatin, amphotericin B and gramicidin A: implications for pores in plasma membranes....Pages 241-250
Ion transport via alamethicin channels....Pages 251-272
Front Matter....Pages 273-273
Neuronal uptake processes for amine and amino acid transmitters....Pages 275-286
Drugs and ions influencing noradrenaline uptake and accumulation in smooth muscle cells....Pages 287-295
The formation of some acidic metabolites in the brain, and their subsequent transport....Pages 297-308
The effects of drugs on the concentrations of some organic acids in human cerebrospinal fluid....Pages 309-315
The transport systems for sugars in the small intestine. Reconstitution of one of them....Pages 317-328
Front Matter....Pages 273-273
Pharmacological significance of new concepts for hexose transfers in erythrocytes....Pages 329-340
The effects of some centrally acting drugs on the hexose transfer system in human erythrocytes....Pages 341-346
Effects of lithium on choline transport in synaptosomes and human erythrocytes....Pages 347-367
Back Matter....Pages 369-376