Drug utilization research: methods and applications

Content: List of contributors   List of reviewers    Acknowledgements    About the companion website    Part 1 -INTRODUCTION      1 INTRODUCTION TO DRUG UTILIZATION RESEARCH Bjorn Wettermark, Monique Elseviers, Anna Birna Almarsdottir, Morten Andersen, Ria Benko, Marion Bennie, Irene Eriksson, Brian Godman, Janet Krska, Elisabetta Poluzzi, Katja Taxis, Robert Vander Stichele, Vera  Vlahoviae-Paleevski    Part 2    METHODOLOGY    2 STUDY DESIGNS IN DRUG UTILIZATION RESEARCH  Bjorn Wettermark, Mirko Di Martino, Monique Elseviers    3 PRIMARY DATA COLLECTION FOR DRUG UTILIZATION RESEARCH Tatiana Chama Borges Luz, Evalill Nilsson    4 SECONDARY DATA SOURCES FOR DRUG UTILIZATION RESEARCH Irene Eriksson, Luisa Ibanez    5 CLASSIFICATION SYSTEMS FOR DRUGS AND DISEASES Marit Ronning, Stuart McTaggart    6 MEASUREMENT UNITS OF DRUG UTILIZATION Hege Salvesen Blix    7 INDIVIDUAL LEVEL DRUG UTILIZATION ANALYSES Jesper Hallas, Henrik Stovring, Anton Pottegard    8 MEASUREMENT OF DRUG EXPENDITURE Sabine Vogler, Jaana E. Martikainen    9 BASIC STATISTICAL METHODS IN DRUG UTILIZATION RESEARCH  Douglas T Steinke, Monique M Elseviers    10 VISUALIZATION OF DRUG UTILIZATION DATA Maria Matuz, Ria Benko, Mikael Hoffmann    11 MULTILEVEL ANALYSES IN DRUG UTILIZATION RESEARCH  Juan Merlo    12 DEFINING AND DEVELOPING QUALITY INDICATORS FOR DRUG UTILIZATION  Stephen Campbell, Bjorn Wettermark, Morten Andersen    13 QUALITATIVE METHODS IN DRUG UTILIZATION RESEARCH Anna Birna Almarsdottir, Pia Bastholm Rahmner    Part 3 - APPLIED DRUG UTILIZATION RESEARCH     Section A - COMPARATIVE DRUG UTILIZATION RESEARCH    14 COMPARISON OF DRUG UTILIZATION ACROSS DIFFERENT GEOGRAPHICAL AREAS  Vera Vlahoviae-Paleevski, Bjorn Wettermark, Luisa Ibanez, Robert Vander Stichele    15 COMPARISON OF DRUG UTILIZATION IN DIFFERENT HEALTH CARE SETTINGS  Sean MacBride-Stewart, Ksenia Zagorodnikova, Irene Langner, Gisbert W Selke      16 TIME-DEPENDENT AND SEASONAL VARIATION IN DRUG UTILIZATION Eric Van Ganse, Laurent Laforest , Niels Adriaenssens    17 COMPARATIVE STUDIES ON PATIENT AND PRESCRIBER CHARACTERISTICS Irene Eriksson, Ulf Bergman, Vera Vlahoviae-Paleevski, Mia von Euler    18 COMPARATIVE  STUDIES ON HEALTH SYSTEMS  Tatiana Chama Borges Luz, Claudia Osorio-de-Castro, Bjorn Wettermark    Section B - DRUG UTILIZATION AND HEALTH POLICY     19 INTRODUCTION TO DRUG UTILIZATION AND HEALTH POLICY   Brian Godman, Hye-Young Kwon, Marion Bennie, Anna Birna Almarsdottir    20 MANAGED INTRODUCTION OF NEW DRUGS  Brian Godman, Roberta Joppi, Marion Bennie, Saira Jan, Bjorn Wettermark    21 MANAGEMENT OF DRUGS IN THE HEALTH CARE SYSTEM Brian Godman, Marion Bennie, Claudia Osorio-de-Castro, Vu Thi Thu Huong, Saira Jan    22 PHARMACEUTICAL INDUSTRY AND HEALTH POLICY  Richard Torbett, Donald Han, Indranil Bagchi    Secion B - DRUG UTILIZATION IN SPECIFIC POPULATIONS     23 DRUG UTILIZATION IN PREGNANT WOMEN  Hedvig Nordeng    24 DRUG UTILIZATION IN THE PAEDIATRIC POPULATION Antje Neubert, Katja Taxis, Ian Wong    25 DRUG UTILIZATION IN OLDER PEOPLE  Katja Taxis, David O   Sullivan, Shane Cullinan, Stephen Byrne    Section C - DRUG UTILIZATION IN SPECIFIC THERAPEUTIC AREAS      26 DRUG UTILIZATION RESEARCH IN THE AREA OF ANTIBIOTICS  Ria Benko, Marion Bennie, Samuel Coenen    27 DRUG UTILIZATION RESEARCH IN THE AREA OF CARDIOVASCULAR MEDICINES  Elisabetta Poluzzi, Maarit Jaana Korhonen    28 DRUG UTILIZATION RESEARCH IN THE AREA OF ANALGESICS AND PSYCHOTROPICS  Helga Zoega, Alesha Smith, Nadia Barozzi    29 DRUG UTILIZATION RESEARCH IN THE AREA OF BIOLOGICALS Carlo Piccinni, Luigi Naldi , Martin Neovius    30 DRUG UTILIZATION RESEARCH IN THE AREA OF CANCER DRUGS  Nils Wilking, Thomas Hofmarcher, Ulla Wilking, Bengt Jonsson    Section D - DETERMINANTS OF DRUG UTILIZATION     31 HEALTH SYSTEM PERSPECTIVES    Paul Spivey, Brian Godman    32 PRESCRIBER PERSPECTIVES  Colin Bradley, Kathleen Holloway, Janet Krska    33 PATIENT PERSPECTIVES Janine Traulsen, Nicky Britten, Janet Krska    Section E - ADHERENCE AND DRUG UTILIZATION RESEARCH    34 AN INTRODUCTION TO ADHERENCE RESEARCH Bernard Vrijens    35 ASSESSMENT OF MEDICATION ADHERENCE IN FIELD RESEARCH  Monique Elseviers, Bernard Vrijens    36 ASSESSMENT OF ADHERENCE TO DRUG TREATMENT IN DATABASE RESEARCH  Jean-Pierre Gregoire, Jocelyne Moisan    37 INTERVENTIONS TO IMPROVE ADHERENCE TO DRUG TREATMENT  Marie Paule Schneider, Jennifer Celio, Yoleen van Camp, Matthias Cavassini    Section F - THE ROLE OF DRUG UTILIZATION WITHIN THE FIELD OF PHARMACOEPIDEMIOLOGY    38 DRUG UTILIZATION RESEARCH AND RISK MANAGEMENT  Giampiero Mazzaglia, Peter Mol    39 DRUG UTILIZATION RESEARCH AND METHODS OF PHARMACOVIGILANCE Emanuel Raschi, Fabrizio De Ponti    40 DRUG UTILIZATION RESEARCH AND THE REGULATOR   S PERSPECTIVE IN PHARMACOVIGILANCE Xavier Kurz, Kevin Blake    41 DRUG UTILIZATION RESEARCH AND OUTCOME RESEARCH  Henrik Toft Sorensen, Gianluca Trifiro    42 DRUG UTILIZATION RESEARCH AND PHARMACOECONOMICS  Cara Usher, Kathleen Bennett, Lorenzo G Mantovani, Dyfrig Hughes    Section G - ASSESSMENT AND IMPROVEMENT OF THE QUALITY OF MEDICINE USE     43 QUALITY INDICATORS FOR PRESCRIBING     WHAT DO WE MEASURE?  Petra Denig, Flora Haaijer-Ruskamp, Lisa Pont    44 QUALITY INDICATORS FOR PATIENT CARE IN PHARMACY PRACTICE  Hanne Herborg    45 INTERVENTIONS WHICH INFLUENCE PRESCRIBING DECISIONS AND DRUG UTILIZATION Jens Sondergaard, Dorte Gilsa Hansen, Debra Rowett    46 DEVELOPMENT, DELIVERY AND EVALUATION OF IMPLEMENTATION PROGRAMS   Elizabeth Roughead, Andrew Gilbert    47 TOWARDS BETTER UNDERSTANDING OF PRESCRIBING- ENHANCEMENT  INTERVENTIONS   Frank May    Part 4 -EPILOGUE      48 THE MANY FUTURES OF DRUG UTILIZATION RESEARCH Hubert GM Leufkens, Frank May, Nicky Britten    Glossary    Index