Drug delivery at the nanoscale - A guide for scientists, physicians and lawyers

PART A
Drug Delivery at the Nanoscale: A Guide for Scientists, Physicians and Lawyers
Raj Bawa, MS, PhD
What Is Precision Medicine? A Primer on Contemporary Issues and Concerns
Kadija Ferryman, PhD, and Mikaela Pitcan, PhD
FDA’s Role in Paving the Way for Personalized Medicine
U.S. Food and Drug Administration
Multifunctional Gold Nanoparticles in Drug Delivery Systems
Zachary I. Stryker, Mehdi Rajabi, PhD, and Shaker A. Mousa, PhD
Nanoparticles and Nanoparticulate Drug Delivery Systems: Impact of Size and Structure on Functionality
Ajit S. Narang, PhD, Rong-Kun Chang, PhD, and Munir A. Hussain, PhD
Self-Assembling Peptide Amphiphiles as a Versatile Future Nanomedicine Platform
Run Chang, MS, and Thomas J. Webster, PhD
Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery
Schuyler A Pruyn, BSc, Mehdi Rajabi, PhD, Mary Adeyeye, BSc, and Shaker A. Mousa, PhD
Nanomaterials: Tools, Technology, and Methodology of Nanotechnology-Based Biomedical Systems for Diagnostics and Therapy
Christian Schmidt, PhD, and Joachim Storsberg, PhD
Nanomagnetic Resonance Imaging (Nano-MRI) Gives Personalized Medicine a New Perspective
Lorenzo Rosa, PhD, Jonathan Blackledge, and Albert Boretti, PhD
Advancing Precision Medicine: Tailoring Personalized Therapies
Kyle B. Matchett, PhD, Niamh Lynam-Lennon, PhD, R. William Watson, PhD, and James A. L. Brown, PhD
Precision Medicine for Alzheimer’s Disease Prevention
Cara L. Berkowitz, BA, Lisa Mosconi, PhD, Olivia Scheyer, BA, Aneela Rahman, BA, Hollie Hristov, FNP, and Richard S. Isaacson, MD
Advanced Porphyrin Nanomaterials for Biological Applications
Haoyuan Huang, PhD, and Jonathan F. Lovell, PhD
Cerium Oxide Nanoparticles as a Novel Reactive Oxygen Modulating Nanodrug
Ece Alpaslan, PhD, and Thomas J. Webster, PhD
Artificial Nanomachines and Nanorobotics
Alexandre Loukanov, PhD, DSc, Hristo Gagov, PhD, and Seiichiro Nakabayashi, PhD
Nanomotors for Nucleic Acid, Protein, Pollutant, and Cell Detection
Alejandro Baeza, PhD, and María Vallet-Regí, PhD
Magneto-Responsive Scaffolds for Tissue Engineering Applications
Adedokun A. Adedoyin, PhD, and Adam K. Ekenseair, PhD
Anti-Cancer and Anti-Angiogenic Properties of Nano-Diamino-Tetrac, A Thyroid Hormone Derivative
Paul J. Davis, MD, and Shaker A. Mousa, MBA, PhD
PART B
Proteomic Profiling and Predictive Biomarkers in Neuro-Traumatology and Neuro-Oncology
Mario Ganau, MD, PhD, Nikolaos Syrmos, MD, MSc, Marco Paris, MD, and Lara Prisco, MD, MSc
Nanomedicine and Personalized Care: Facts and Fiction
David M. Berube, PhD and Emily Winderman, PhD
Precision Immuno-Oncology: Prospects of Individualized Immunotherapy for Pancreatic Cancer
Jiajia Zhang, MD, MPH, Christopher L. Wolfgang, MD, MS, PhD, and Lei Zheng, MD, PhD
Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment
Vivek Podder, MBBS, Binod Dhakal, MD, Gousia Ummae Salma Shaik, MD, Kaushik Sundar, DM, Madhava Sai Sivapuram, MBBS, Vijay Kumar Chattu, MD, and Rakesh Biswas, MD
Views from the FDA: Precision Medicine, Genetic Variant Databases and Companion Diagnostics
U.S. Food and Drug Administration
Protein-Based Nanoparticle Materials for Medical Applications
Kelsey DeFrates, BSc, Theodore Markiewicz, BSc, Pamela Gallo, BSc, Aaron Rack, BSc, Aubrie Weyhmiller, BSc, Brandon Jarmusik, BSc, and Xiao Hu, PhD
Nanomedicine and Phage Capsids
Philip Serwer, PhD, and Elena T. Wright
Pharmacogenomics: Ethical, Social, and Public Policy Issues
Yann Joly, PhD, and Denise Avard, PhD
From Single Level Analysis to Multi-Omics Integrative Approaches: A Powerful Strategy towards the Precision Oncology
Maria Eugenia Gallo Cantafio, PhD, Katia Grillone, PhD, Daniele Caracciolo, MD, Francesca Scionti, PhD, Mariamena Arbitrio, MD, Vito Barbieri, MD, Licia Pensabene, MD, Pietro Hiram Guzzi, PhD, and Maria Teresa Di Martino, PhD
Harmonizing Outcomes for Genomic Medicine: Comparison of eMERGE Outcomes to ClinGen Outcome/Intervention Pairs
Janet L. Williams, MS, Wendy K. Chung, MD, PhD, Alex Fedotov, PhD, Krzysztof Kiryluk, MD, Chunhua Weng, PhD, John J. Connolly, PhD, Margaret Harr, MS, Hakon Hakonarson, MD, PhD, Kathleen A. Leppig, MD, Eric B. Larson, MD, Gail P. Jarvik, MD, PhD, David L. Veenstra, Pharm D, PhD, Christin Hoell, MS, Maureen E. Smith, MS, Ingrid A. Holm, MD, MPH, Josh F. Peterson, MD, MPH, and Marc S. Williams, MD
Estrogen and Androgen Blockade for Advanced Prostate Cancer in the Era of Precision Medicine
Tetsuya Fujimura, MD, PhD, Kenichi Takayama, MD, PhD, Satoru Takahashi, MD, PhD, and Satoshi Inoue, MD, PhD
Precision or Personalized Medicine for Cancer Chemotherapy: Is There a Role for Herbal Medicine?
Zhijun Wang, PhD, Xuefeng Liu, MD, Rebecca Lucinda Ka Yan Ho, MSc, Christopher Wai Kei Lam, PhD, and Moses Sing Sum Chow, PharmD
Personomics: The Missing Link in the Evolution from Precision Medicine to Personalized Medicine
Roy C. Ziegelstein, MD
Stem Cell Banking for Regenerative and Personalized Medicine
David T. Harris, PhD
Overview of Ethical Issues in Nanomedicine
Raj Bawa, MS, PhD, and Summer Johnson, PhD
Amphiphilic Nanocarrier Systems for Curcumin Delivery in Neurodegenerative Disorders
Miora Rakotoarisoa, MS, and Angelina Angelova, PhD
Peptide-Based Drug Delivery Systems: Future Challenges, Perspectives, and Opportunities in Nanomedicine
Diego Tesauro, PhD, Antonella Accardo, PhD, Carlo Diaferia, PhD, Vittoria Milano, PhD, Jean Guillon, PhD, Luisa Ronga, PhD, and Filomena Rossi, PhD
Hydrogels and Their Applications in Targeted Drug Delivery
Radhika Narayanaswamy, MSc, and Vladimir P. Torchilin, PhD, DSc
Emergence of Real World Evidence in Precision Medicine
Neil A. Belson, MS, JD