Dipeptidyl Aminopeptidases in Health and Disease

Dipeptidyl Peptidase IV Substrates....Pages 3-17
Structure-Function Relationship of DPP IV: Insights into its Dimerisation and Gelatinase Activity....Pages 19-27
Exploration of the Active Site of Dipeptidyl Peptidase IV From Porphyromonas gingivalis ....Pages 29-35
Modification of the Biological Activity of Chemokines by Dipeptidyl Peptidase IV — a Side Effect in the Use of Inhibitors?....Pages 37-47
Molecular Chimeras and Mutational Analysis in the Prolyl Oligopeptidase Gene Family....Pages 49-55
The Specificity of DP IV for Natural Substrates is Peptide Structure Determined....Pages 57-63
New Results on the Conformations of Potent DP IV (CD26) Inhibitors bearing the N-terminal MWP Structural Motif....Pages 65-68
Different Inhibition Mechanisms of Dipeptidyl Peptidase IV by Tryptophan Containing Peptides and Amides....Pages 69-72
Re-Uptake Mechanisms of Peptide Fragments after DPP IV-Mediated Proteolysis in the Peripheral Nervous System....Pages 73-76
Dipeptidyl Peptidase IV Gene Family....Pages 79-86
Seprase-DPPIV Association and Prolyl Peptidase and Gelatinase Activities of the Protease Complex....Pages 87-94
Dipeptidyl Peptidase-IV Activity and/or Structure Homologues (DASH) in Transformed Neuroectodermal Cells....Pages 95-102
Characterisation of Human DP IV Produced by a Pichia pastoris Expression System....Pages 103-108
Isolation and Characterization of Attractin-2....Pages 109-113
Investigation of DP IV-dependent Protein-Protein Interactions using Surface Plasmon Resonance....Pages 115-119
Synergistic Action of DPIV and APN in the Regulation of T Cell Function....Pages 123-131
CD26/DPP IV in Experimental and Clinical Organ Transplantation....Pages 133-143
CD26 is Involved in the Regulation of T-Cell Plasma Membrane Compartmentation....Pages 145-153
Inhibition of Dipeptidylpeptidase IV (DPP IV, CD26) Activity Modulates Surface Expression of CTLA-4 in Stress-Induced Abortions....Pages 155-163
Dipeptidyl Peptidase IV/CD26 in T Cell Activation, Cytokine Secretion and Immunoglobulin Production....Pages 165-174
Dipeptidyl Peptidase IV Inhibitors with the N-terminal MXP Sequence: Structure-Activity-Relationships....Pages 175-179
On the Role of Dipeptidyl Peptidase IV in the Digestion of an Immunodominant Epitope in Celiac Disease....Pages 181-187
The Properties of Human and Bovine CD8+CD26+ T Cells Induced by a Microbial Superantigen....Pages 189-193
DPPIV and Seprase in Cancer Invasion and Angiogenesis....Pages 197-203
Glutamate Carboxypeptidase II Inhibition as a Novel Therapeutic Target....Pages 205-213
Dual Role of Dipeptidyl Peptidase IV (DPP IV) in Angiogenesis and Vascular Remodeling....Pages 215-222
CD26 Expression on Cutaneous Infiltrates from Patients with Cutaneous T-Cell Lymphoma (CTCL)....Pages 223-234
Intrahepatic Expression of Collagen and Fibroblast Activation Protein (FAP) in Hepatitis C Virus Infection....Pages 235-243
Expression of CD26/Dipeptidyl Peptidase IV in Endometrial Adenocarcinoma and its Negative Correlation with Tumor Grade....Pages 245-248
Adhesion Potency to Mesothelial Cells by Overexpression of Dipeptidyl Peptidase IV....Pages 249-252
Survival Time and Invasive Activity due to Dipeptidyl Peptidase IV Overexpression in Ovarian Carcinoma....Pages 253-256
Dipeptidylpeptidase IV Activities in Prostatic Secretions....Pages 257-260
Implementation of GLP-1 Based Therapy of Type 2 Diabetes Mellitus Using DPP-IV Inhibitors....Pages 263-279
Dipeptidyl Peptidase IV Inhibition in Animal Models of Diabetes....Pages 281-291
Glucose-dependent Insulinotropic Polypeptide (GIP): Development of DP IV-Resistant Analogues with Therapeutic Potential....Pages 293-301
Neutral Endopeptidase 24.11 and Dipeptidyl Peptidase IV are Both Involved in Regulating the Metabolic Stability of Glucagon-like Peptide-1 in vivo ....Pages 303-312
DPP IV, Immune Parameters, and Psychometrical Variables in Patients with Eating Disorders....Pages 313-320
DPP IV and Mental Depression in Crohn’s Disease....Pages 321-331
Microscopic Acid-Base Equilibra of Alanyl-boroAlanine....Pages 333-338
Acylated Hydroxamates as Selective and Highly Potent Inhibitors of Dipeptidyl Peptidase I....Pages 339-343
CD26-/DPP IV-Positive Lymphocytes in Murine Acute Experimental Colitis....Pages 345-350
Neuroprotective Effects of Inhibitors of Dipeptidyl Peptidase-IV In Vitro and In Vivo....Pages 351-355