Developmental Patterning of the Vertebrate Limb

Front Matter....Pages i-xi
Some Problems in Limb Development....Pages 1-7
The Molecular Basis of Limb Patterning: A Review....Pages 9-14
Expression of the Msh-Like Homebox-Containing Genes during Mouse Limb Development....Pages 15-23
The Limb Deformity Gene Encodes Evolutionarily Highly Conserved Proteins....Pages 25-30
The Role of Homeobox Genes in Amphibian Limb Development and Regeneration....Pages 31-35
Homeobox-Containing Genes and GAP Junctional Communication in Pattern Formation during Chick Limb Development....Pages 37-43
Functional Studies of Genes in the Limb....Pages 45-54
HOX-7: Temporal Patterns of Expression in Normal and Limbless Chick Embryos....Pages 55-56
Expression Profile of Two Homeoboxgenes during Chicken Embryogenesis....Pages 57-59
Characterization of Three Zebrafish Genes Related to Hox-7....Pages 61-63
A Comparison of the Expression Domains of the Murine Hox-4, RARs and CRABP Genes Suggests Possible Functional Relationships During Patterning of the Vertebrate Limb....Pages 65-73
Retinoic Acid Nuclear Receptors....Pages 75-88
The Role of Retinoic Acid and Cellular Retinoic Acid-Binding Protein in the Regenerating Amphibian Limb....Pages 89-96
Retinoic Acid Treatment Alters the Pattern of Retinoic Acid Receptor Beta Expression in the Embryonic Chick Limb....Pages 97-100
Expression Pattern of an RXR Nuclear Receptor Gene in the Chick Embryo....Pages 101-104
Retinoic Acid and Limb Pattern Formation in Cell Culture....Pages 105-113
Growth Factors Produced by the Polarising Zone — A Complement to the Retinoic Acid System....Pages 115-122
Biochemical and Molecular Aspects of Retinoid Action in Limb Pattern Formation....Pages 123-132
Position-Dependent Properties of Limb Cells....Pages 133-142
Retinoic Acid and Limb Patterning and Morphogenesis....Pages 143-149
Does Retinoic Acid Organise a Limb or Induce a ZPA?....Pages 151-155
Retinoic Acid Effects on Experimental Chick Wing Buds: Patterns of Cell Death and Skeletogenesis....Pages 157-160
A Comparison of Reaction Diffusion and Mechanochemical Models for Limb Development....Pages 161-163
The Pathway of Polarizing Activity from Hensen’s Node To the Wing Bud in the Chick Embryo....Pages 165-170
Extracellular Matrix in Early Limb Development....Pages 171-176
Molecular Heterogeneity of Chondroitin Sulphate in the Developing Chick Limb....Pages 177-188
Special Properties of the AER/Mesenchyme Interface in the Chick Wing Bud: Analysis of ECM Molecules and Integrin Receptors....Pages 189-202
Physical Forces and Pattern Formation in Limb Development....Pages 203-210
Extracellular Material Organization and Long Tendon Formation in the Chick Leg Autopodium. In Vivo and in Vitro Study....Pages 211-213
Hyaluronan-Cell Interactions in Limb Development....Pages 215-223
Role of the Transforming Growth Factor- β (TGF- β ) Family, Extracellular Matrix, and GAP Junctional Communication in Limb Cartilage Differentiation....Pages 225-233
Vascular Involvement in Cartilage and Bone Development....Pages 235-241
Patterning of Connective Tissues in the Regenerating Amphibian Limb....Pages 243-248
The Interdigital Spaces of the Chick Leg Bud as a Model for Analysing Limb Morphogenesis and Cell Differentiation....Pages 249-259
A “Packaging” Model of Limb Development....Pages 261-263
The Somite-Muscle Relationship in the Avian Embryo....Pages 265-271
Observations Concerning the Control of Directed Myogenic Cell Migration....Pages 273-284
Extracellular Matrix and Muscle Formation....Pages 285-292
Control of Muscle Morphogenesis and Endplate Pattern in Limb Muscles of Avian Chimeras....Pages 293-297
Review of the Extracellular Matrix in Relation to Limb Development....Pages 299-301
The Evolution of Connective and Skeletal Tissues....Pages 303-311
Developmental Approaches to the Problem of Transformation of Limb Structure in Evolution....Pages 313-323
New Palaeontological Contributions to Limb Ontogeny and Phylogeny....Pages 325-337
The Fin-Limb Transformation: Palaeontological and Embryological Evidence....Pages 339-345
The Development of the Teleost Fin and Implications for Our Understanding of Tetrapod Limb Evolution....Pages 347-354
Phylogenetically Ancient Pattern in Ontogenesis of Limb Muscles....Pages 355-363
Mutation and Limb Evolution....Pages 365-371
Insights into Limb Development and Pattern Formation from Studies of the Limbless and Talpid 2 Chick Mutants....Pages 373-383
Proximal Elements in the Vertebrate Limb: Evolutionary and Developmental Origin of the Pectoral Girdle....Pages 385-394
Evolutionary Transformation of Limb Pattern: Heterochrony and Secondary Fusion....Pages 395-405
Plasticity in Skeletal Development: Knee-Joint Morphology in Fibula-Deficient Chick Embryos....Pages 407-409
The Implications of “The Bauplan” for Development and Evolution of the Tetrapod Limb....Pages 411-421
Molecular Biology and Evolution: Two Perspectives....Pages 423-438
The Developmental Basis of Limb Evolution: A Review....Pages 439-442
Back Matter....Pages 443-452