Dendritic Cells in Fundamental and Clinical Immunology

Front Matter....Pages i-xvi
Dendritic Cells: Antigen Presentation, Accessory Function and Clinical Relevance....Pages 1-9
Endocytic Activity of Dendritic Cells is Similar to Other Antigen Presenting Cells....Pages 11-15
Immunocytochemical Characterization of Dendritic Cells....Pages 17-21
Requirements of Exogenous Protein Antigens for Presentation to CD4 + T lymphocytes By MHC Class II-Positive APC....Pages 23-27
Modulation of MHC Class II Determinants on Rat Langerhans Cells During Short Term Culture....Pages 29-34
A Dendritic Cell Specific Determinant Present In Endosomes Is Involved in the Presentation of Protein Antigens....Pages 35-39
Dendritic Cells are Potent Antigen-Presenting Cells for Microbial Superantigen....Pages 41-46
Divergent T-cell Cytokine Profiles Induced by Dendritic Cells from Different Tissues....Pages 47-52
Adhesion Molecules: Co-Stimulators and Co-Mitogens in Dendritic Cell - T Cell Interaction....Pages 53-58
Dendritic Cell Dependent Expression of IgA By Clones in T/B Microcultures....Pages 59-64
Adhesion Molecules in Tonsil DC-T Cell Interactions....Pages 65-69
Dendritic Cells Have Reduced Cell Surface Membrane Glycoproteins Including CD43 Determinants....Pages 71-73
The Effect of Human Dendritic Cells on the Lectin-Induced Responsiveness of CD4 + T Cells To IL-2 and IL-4....Pages 75-80
Analysis of Cytokine and Cytokine Receptor Production by Human Dendritic Cells....Pages 81-85
Costimulating Factors and Signals Relevant for Antigen Presenting Cell Function....Pages 87-92
Distinct T Cell Stimulation Mechanism and Phenotype of Human Blood Dendritic Cells....Pages 93-98
The Role Of Dendritic Cells in the Regulation of T Cell Cytokine Synthesis....Pages 99-104
The Role of Dendritic Cells as Co-Stimulators in Tolerance Induction....Pages 105-110
The Influence of Dendritic Cells on T-Cell Cytokine Production....Pages 111-115
Phenotypical and Functional Characterization of Dendritic Cells in the Human Peritoneal Cavity....Pages 117-122
Dendritic Cells Isolated From Rat and Human Non-Lymphoid Tissue are Very Potent Accessory Cells....Pages 123-127
Antigen Presenting Capacity of Peritoneal Macrophages and Dendritic Cells....Pages 129-134
T-Cell Repertoire Development in MHC Class II Deficient Humans....Pages 135-140
Rat Thymic Dendritic Cells....Pages 141-146
Rat Thymic Dendritic Cells: Flow Cytometry Analysis....Pages 147-152
Ultrastructure of Interdigitating Cells in the Rat Thymus During Cyclosporin A Treatment....Pages 153-157
T Cell Tolerance and Antigen Presenting Cell Function in the Thymus....Pages 159-164
Tolerizing Mice to Human Leukocytes: A Step Toward the Production of Monoclonal Antibodies Specific for Human Dendritic Cells....Pages 165-172
Morphological and Functional Differences Between HLA-DR+ Peripheral Blood Dendritic Cells and HLA-DR+ FN-Alpha Producing Cells....Pages 173-178
Three Monoclonal Antibodies to Antigen Presenting Cells in the Rat with Differential Influence on Cellular Interactions....Pages 179-184
The MHC Expression of Dendritic Cells from Mouse Spleen Isolated by Centrifugal Elutriation is Upregulated During Short Term Culture....Pages 185-189
IL-6 and Its High Affinity Receptor During Differentiation of Monocytes into Langerhans Cells....Pages 191-198
Phagocytosis of Antigens by Langerhans Cells....Pages 199-204
Dissection of Human Langerhans Cell Allostimulatory Function. Modulation by Interferon-γ.....Pages 205-208
Human in Vitro T Cell Sensitization Using Hapten-Modified Epidermal Langerhans Cells....Pages 209-212
Monocyte-Derived Langerhans Cells from Different Species - Morphological and Functional Characterization....Pages 213-218
A Serial Section Study on Mice Langerhans Cell Granules After DNFB Painting....Pages 219-224
Skin Dendritic Cell - Lymphocyte Interactions in Autologous System....Pages 225-230
Induction of the Low Affinity Receptor for IgE (FcεRII/CD23) on Human Blood Dendritic Cells by Interleukin-4....Pages 231-236
FcεRI Mediates IgE-Binding to Human Epidermal Langerhans Cells....Pages 237-241
Murine Epidermal Langerhans Cells as A Model to Study Tissue Dendritic Cells....Pages 243-249
Differentiation of Dendritic Cells in Cultures of Rat and Mouse Bone Marrow Cells....Pages 251-255
TNF and GM-CSF Dependent Growth of an Early Progenitor of Dendritic Langerhans Cells in Human Bone Marrow....Pages 257-262
Human Bone Marrow Contains Potent Stimulatory Cells for the Allogeneic MLR With the Phenotype of Dendritic Cells....Pages 263-268
Recombinant GM-CSF Induces in Vitro Differentiation of Dendritic Cells from Mouse Bone Marrow....Pages 269-273
Signals Required for Differentiating Dendritic Cells from Human Monocytes in Vitro....Pages 275-280
Down-Regulation and Release of CD14 On Human Monocytes by IL-4 Depends on the Presence of Serum Or GM-CSF....Pages 281-286
Serum-Free Differentiation of Rat and Human Dendritic Cells, Accompanied by Acquisition of the Nuclear Lamins A/C as Differentiation Markers....Pages 287-291
Immunophenotypic and Ultrastructural Differentiation and Maturation of Nonlymphoid Dendritic Cells in Osteopetrotic ( op ) Mice with the Total Absence of Macrophage Colony Stimulating Factor Activity....Pages 293-297
Loading of Dendritic Cells with Antigen in Vitro Or in Vivo by Immunotargeting can Replace the Need for Adjuvant....Pages 299-303
Migration of Alveolar Macrophages from Alveolar Space to Paracortical T Cell Area of the Draining Lymph Node....Pages 305-310
Comparison of Langerhans Cells and Interdigitating Reticulum Cells....Pages 311-314
Migration of Dendritic Cells During Contact Sensitization....Pages 315-320
Peritoneal Cell Labelling: A Study on the Migration of Macrophages and Dendritic Cells Towards the GUT....Pages 321-326
Dendritic Cells “in Vivo”: Migration and Antigen Handling....Pages 327-332
Follicular Dendritic Cells: Isolation Procedures, Short and Long Term Cultures....Pages 333-338
Heterogeneity and Cellular Origin of Follicular Dendritic Cells....Pages 339-344
Differential Uptake and Trapping of TI-2 Antigens: an Unexpected Role for Follicular Dendritic Cells in the Induction of TI-2 Immune Responses....Pages 345-351
Ultrastructural Heterogeneity of Follicular Dendritic Cells in the Human Tonsil....Pages 353-358
Ultrastructural Analysis of Human Lymph Node Follicles After HIV-1 Infection....Pages 359-363
Emperipolesis of Lymphoid Cells by Human Follicular Dendritic Cells in Vitro....Pages 365-370
The Localization of Lymphokines in Murine Germinal Centers....Pages 371-376
Two Different Mechanisms of Immune-Complex Trapping in the Mouse Spleen During Immune Responses....Pages 377-382
Cellular Requirements for Functional Reconstitution of Follicular Dendritic Cells in Scid Mice....Pages 383-386
Interaction Through the Lfa-1/Icam-1 Pathway Prevents Programmed Cell Death of Germinal Center B Cells....Pages 387-392
Membrane Expression of Fc∈RII/CD23 and Release of Soluble CD23 by Follicular Dendritic Cells....Pages 393-398
Follicular Dendritic Cells in Malignant Lymphomas - Distribution, Phenotypes & Ultrastructures....Pages 399-404
Lymphoid Follicles in Cynomolgus Monkeys after Infection with Simian Immunodeficiency Virus....Pages 405-409
Destruction of Follicular Dendritic Cells in Murine Acquired Immunodeficiency Syndrome (Maids)....Pages 411-416
Changes in Follicular Dendritic Cell and CD8+ Cell Function in Macaque Lymph Nodes Following Infection with Siv 251 ....Pages 417-423
Rapid and Selective Isolation of Follicular Dendritic Cells by Low Speed Centrifugations on Discontinuous BSA Gradients....Pages 425-429
Follicular Dendritic Cells Do Not Produce TNF-α Nor its Receptor....Pages 431-436
Splenic Lesions in Hypogammaglobulinaemia....Pages 437-441
Ontogenic Study on the Bronchus-Associated Lymphoid Tissue (Balt) in the Rat, with Special Reference to Dendritic Cells....Pages 443-447
DRC 1 Expression on Normal and Pathological Lymphoid Cells....Pages 449-453
Binding of HIV-1 to Human Follicular Dendritic Cells....Pages 455-460
Follicular Dendritic Cells in Germinal Center Reactions....Pages 461-465
Follicular Dendritic Cells and Dendritic Cell Nomenclature....Pages 467-468
Langerhans Cells as Outposts of the Dendritic Cell System....Pages 469-480
Heterogeneity of Dendritic Cells and Nomenclature....Pages 481-486
Report of the Panel Discussion....Pages 487-488
Dendritic Cells in Transplantation....Pages 489-494
Down-Regulation of MHC-Expression on Dendritic Cells in Rat Kidney Grafts by Puva Pretreatment....Pages 495-499
Cytokine Mediators of Non-Lymphoid Dendritic Cell Migration....Pages 501-506
Isolation of Dendritic Leukocytes from Non-Lymphoid Organs....Pages 507-512
RT1B/D+ Non-Lymphoid DC in Early GVHD and Hg-Induced Autoimmunity of Rat Salivary and Lacrimal Glands....Pages 513-519
In-Vitro Infection of Peripheral Blood Dendritic Cells with Human Immunodeficiency Virus-1 Causes Impairment of Accessory Functions....Pages 521-526
Simian Immunodeficiency Virus (SIV) Induced Alterations of Thymus IDCs....Pages 527-531
Murine Leukaemia Virus Infections as Models For Retroviral Disease in Humans....Pages 533-537
Langerhans Cells and Interdigitating Cells in Hiv-Infection....Pages 539-544
Dendritic Cells in HIV-1 and HTLV-1 Infection....Pages 545-549
Dendritic Cells in Allergic and Chronic Inflammatory Responses....Pages 551-555
Pulmonary Dendritic Cell Populations....Pages 557-562
Blood Dendritic Cells are Highly Adherent to Untreated and Cytokine-Treated Cultured Endothelium....Pages 563-569
Antigen Specific T Cell Priming in Vivo by Intratracheal Injection of Antigen Presenting Cells....Pages 571-575
Histology and Immunophenotype of Dendritic Cells in the Human Lung....Pages 577-580
Acquisition of Chlamydial Antigen by Dendritic Cells and Monocytes....Pages 581-586
Experimental Cutaneous Leishmaniasis: Langerhans Cells Internalize Leishmania Major and Induce an Antigen-Specific T-Cell Response....Pages 587-592
Endocytosis of Potential Contact Sensitizers by Human Dendritic Cells....Pages 593-597
Dendritic Cells and “Dendritic” Macrophages in the Uveal Tract....Pages 599-604
Macrophages and Dendritic Cells in Rat Colon in Experimental Inflammatory Bowel Disease....Pages 605-610
Vaccination with Tumor Antigen-Pulsed Dendritic Cells Induces in Vivo Resistance to A B Cell Lymphoma....Pages 611-616
Studies on Langerhans Cells in the Tracheal Squamous Metaplasia of Vitamin A Deficient Rats....Pages 617-621
Depletion of Langerhans Cells Following Carcinogen Treatment is Partly Due to Antigenicity....Pages 623-627
A Proportion of Patients with Premature Ovarian Failure Show Lowered Percentages of Blood Monocyte Derived Dendritic Cells Capable of Forming Clusters with Lymphocytes....Pages 629-632
Thyroid Hormones and Their Iodinated Breakdown Products Enhance the Capability of Monocytes to Mature Into Veiled Cells. Blocking Effects of α-GM-CSF....Pages 633-636
Relationship Between Dendritic Cells and Folliculo-Stellate Cells in the Pituitary: Immunohistochemical Comparison Between Mouse, Rat and Human Pituitaries....Pages 637-642
Dendritic Cells in Tumor Growth and Endocrine Diseases....Pages 643-650
Back Matter....Pages 651-653