Dendritic Cells in Fundamental and Clinical Immunology

Front Matter....Pages i-xix
Characterization of Human CD34 + Derived Dendritic/Langerhans Cells (D-Lc)....Pages 1-5
Stem Cell Factor Enhances Dendritic Cell Development....Pages 7-11
Synergistic Interaction between c-kit Ligand (SCF), GM-CSF and TNF Promotes Optimal Dendritic Langerhans Cell Proliferation from Primitive Progenitors in Human Bone Marrow....Pages 13-16
Progenitor Recruitment and in Vitro Expansion of Immunostimulatory Dendritic Cells from Human CD34 + Bone Marrow Cells by c- kit -Ligand, GM-CSF, and TNFα....Pages 17-20
Thymic Dendritic Cells: Surface Phenotype, Developmental Origin and Function....Pages 21-29
Recombinant GM-CSF Induces Cytokine Production in Mouse Dendritic Cell Clones....Pages 31-34
Review of the Characteristics of Six Cell Lines with Langerhans Cell Phenotype....Pages 35-37
Immortalized Murine Dendritic Cells: Phenotypic and Functional Characterization....Pages 39-41
Production and Properties of Large Numbers of Dendritic Cells from Human Blood....Pages 43-52
A Simplified Method for Growing Dendritic Cells from Rat Bone Marrow....Pages 53-55
Transition of T 3 -Induced Monocyte-Derived Veiled/Dendritic Cells into Macrophage-Like Cells by Lipopolysaccharide....Pages 57-59
Immunophenotypical and Functional Characterization of Bone Marrow Derived Dendritic Cells....Pages 61-63
Expression of B7 Costimulator Molecules on Mouse Dendritic Cells....Pages 65-70
Development of Rat DC by in Vitro Culture of Bone Marrow Cells....Pages 71-73
Dendritic Cells Differentiated from Human Monocytes through a Combination of IL-4, GM-CSF and IFN-γ Exhibit Phenotype and Function of Blood Dendritic Cells....Pages 75-78
Functional CD40 Antigen on B Cells, Dendritic Cells and Fibroblasts....Pages 79-83
Characterization of Human Blood Dendritic Cells: Cytokine Profiles....Pages 85-87
Purification of Human Lung Dendritic Cells by Three Color Flow Cytometry....Pages 89-91
Identification of a Novel Cell Surface Protein Expressed by Murine Epidermal Langerhans Cells and Some Lymphoid Dendritic Cells....Pages 93-95
Characterisation of Adhesion Molecules on the Surface of Dendritic Cells Isolated from Human Blood....Pages 97-99
 In Situ Expression of Activation Markers by Langerhans’ Cells Containing GM-CSF....Pages 101-103
Phenotypic Variation and Functional Differences within Dendritic Cells Isolated from Afferent Lymph....Pages 105-107
Expression of Somatostatin on Langerhans Cells....Pages 109-110
Dermal Dendritic Cells are Important Members of the Skin Immune System....Pages 111-116
Expression of CD44 Antigen by Langerhans Cells and Thy1+ Dendritic Epidermal Cells - Ontogenetic Variation and Its Role in Migration....Pages 117-119
Distribution of Human Colonic Dendritic Cells and Macrophages - Functional Implications....Pages 121-123
Morphologic and Antigenic Features of Dendritic Cells in Immune-Mediated Dermatoses: A Hypothesis of Differentiation....Pages 125-128
Tumor Necrosis Factor Receptors of the Monocyte Derived Langerhans Cell Phenotype “MoLC”....Pages 129-133
Expression of the High Affinity Receptor for Immunoglobulin E (IgE) by Dendritic Cells in Normals and Asthmatics....Pages 135-138
A Comparative Study on Langerhans Cells in Lymph Nodes with Dermatopathic Lymphadenopathy and Histiocytosis X Cells....Pages 139-141
Role of the Interaction of Fibronectin with Epidermal Langerhans Cells in Regulating Their Migratory Pathway....Pages 143-145
Expression of Neuropeptides on Human Epidermal Langerhans Cells....Pages 147-150
Monocyte Derived Dendritic Cells (MODC) Present Phenotype and Functional Activities of Langerhans Cells / Dendritic Cells....Pages 151-153
Development and Distribution of T Cell-Associated Dendritic Cells in Organs and Tissues of Mice Depleted of Blood Monocytes by Administration of Strontium-89....Pages 155-157
Establishment and Characterization of Antigen-Presenting Cell Lines (XS Series) Derived from Newborn Mouse Epidermis....Pages 159-162
Migration of Rat Dendritic Cells and Macrophages from the Peritoneal Cavity to the Parathymic Lymph Nodes....Pages 163-167
 In Vitro Migration Capacity of Epidermal Langerhans Cells....Pages 169-171
Epidermal Langerhans Cell Migration: Signals and Mechanisms....Pages 173-175
Population Dynamics and Functions of Respiratory Tract Dendritic Cells in the Rat....Pages 177-181
Regulation of the Humoral Response by the Antigen-Presenting Cells in Vivo ....Pages 183-185
Antigen Presenting and Primary in Vitro Sensitizing Capacity of CD1a + Dendritic Cells Generated from Human Blood....Pages 187-189
Annexin Expression in Human Dendritic Cells....Pages 191-193
Spleen Accessory Cell Antigen Processing and in vitro Induction of Specific Lymphocyte Proliferation in BALB/c Mice Infested with Nymphal Ixodes ricinus Ticks....Pages 195-197
Functional Dichotomy of Dendritic Cells Isolated from Blood and Lymph Nodes....Pages 199-201
Antigen Processing Capacity of Dendritic Cells from Mice of Different MHC Backgrounds: Down-Regulation upon Culture and Evidence for Heterogeneity of Dendritic Cell Populations....Pages 203-206
TNFα Interrupts Antigen-Presenting Function of Langerhans Cells by Two Mechanisms: Loss of Immunogenic Peptides and Impairment of Antigen-Independent T Cell Clustering....Pages 207-209
The Role of Cis -Urocanic Acid in UVB-Induced Immunosuppression....Pages 211-213
Antigen Processing by Rat Lymph-Borne Dendritic Cells....Pages 215-217
Evidence that Langerhans Cells Migrate to Regional Lymph Nodes During Experimental Contact Sensitization in Dogs....Pages 219-221
Analysis of Invariant Chain Processing in 3 Day Cultured Rat Langerhans Cells....Pages 223-225
Functional and Ultrastructural Aspects of Antigen Processing by Dendritic Cells....Pages 227-231
Processing and Presentation of Protein and Parasite-Derived Antigens by 4F7 + Dendritic Cells....Pages 233-235
Dendritic Cells Migrating from Carcinogen-Treated Skin Have Reduced Antigen-Presenting Function....Pages 237-241
Inhibitory Effects of Ultraviolet B on Human Langerhans Cell Antigen Presenting Function....Pages 243-245
Phenotype of Cells Migrated from Human Skin Explants....Pages 247-251
Uptake of Bead-Adsorbed Versus Soluble Antigen by Bone Marrow Derived Dendritic Cells Triggers Their Activation and Increases Their Antigen Presentation Capacity....Pages 253-255
Ectromelia Virus Establishes a Persistent Infection in Spleen Dendritic Cells and Macrophages of BALB/c Mice following the Acute Disease....Pages 257-261
Functional Expression of ICAM-3 on Human Epidermal Langerhans Cells....Pages 263-265
Multiple Lines of Evidence Favoring a Bone Marrow Derivation of Follicular Dendritic Cells (FDCs)....Pages 267-272
Adhesion and Costimulatory Molecules on Human FDC in Vitro....Pages 273-275
Architectural and Antigenic Features of Follicular Dendritic Cells as a Clue to the Histogenesis of Primary Cutaneous B-Cell Lymphoma....Pages 277-279
An Immunohistochemical Study on Isotypes of the Immune Complexes Trapped by Follicular Dendritic Cells (FDC) in Various Human Lymphoid Tissues....Pages 281-283
The Interdependence of Lymphocyte, Stromal Cell, and Follicular Dendritic Cell Maturation....Pages 285-288
The Monoclonal Antibody FDC-M1 Recognizes Possible Follicular Dendritic Cell Precursors in the Blood and Bone Marrow....Pages 289-291
Expression of Complement Regulating Proteins on FDC....Pages 293-295
Distribution and Characterization of Follicular Dendritic Cells (FDCs) in Non-Hodgkin’s Lymphomas....Pages 297-299
Follicular Dendritic Cells Induce B Cell Activation....Pages 301-304
Germinal Center T Cells: Analysis of Their Proliferative Capacity....Pages 305-307
Iccosomes and Induction of Specific Antibody Production in Vitro....Pages 309-311
Localizations of Regulatory Proteins of Complement Components on RA Synovial Tissues — Especially Germinal Centers....Pages 313-315
In Vitro Immune Complex Binding Assay to Examine the Mechanism of Immune Complex Trapping by Human Follicular Dendritic Cells (FDC)....Pages 317-319
SIV Infection of Follicular Dendritic Cells (FDC) and Other Spleen Cell Subsets in Experimentally Infected Cynomolgus Monkeys....Pages 321-327
Morpho-Functional Changes of Follicular Dendritic Cells (FDC) and Lymph Node Structure in Simian Immunodeficiency Virus (SIV) Infection....Pages 329-331
Modulation of B Lymphocyte Proliferation Inside the Germinal Center....Pages 333-335
Human Follicular Dendritic Cells Promote Both Proliferation and Differentiation of CD40 Activated B Cells....Pages 337-339
Dendritic Cells as Stimulator Cells of MHC Class I-Restricted Immune Responses....Pages 341-345
Dendritic Cells Regulate Development of Alloantigenic and Mitogenic T H l Versus T H 2 Responses....Pages 347-349
New Molecules on Dendritic Cells and Their Interactions with T Lymphocytes....Pages 351-354
Phenotype and Alloactivating Capacity of Dendritic Cells Generated under Different Culture Conditions from Human Peripheral Blood....Pages 355-357
Inhibitory Effect of IL-10 on Human Langerhans Cell Antigen Presenting Function....Pages 359-361
IL-10 Inhibits the Primary Allogeneic T Cell Response to Human Peripheral Blood Dendritic Cells....Pages 363-365
A Molecular Strategy to Identify Molecules that Are Specific for Dendritic Cells and/or Critical to Their Unique Immunostimulatory Function....Pages 367-369
Activation of Primary Allogeneic CD8+ T Cells by Dendritic Cells Generated in Vitro from CD34+ Cord Blood Progenitor Cells....Pages 371-374
Stimulation of Human Anti-Viral CD8+ Cytolytic T Lymphocytes by Dendritic Cells....Pages 375-379
T-Lymphocyte Proliferation Stimulated by αβTCR/CD2 Bispecific Antibody is Dependent on LFA- 1/ICAM-1 Recognition of Accessory Cells....Pages 381-383
Low Reactivity of Peripheral Blood Dendritic Cells Respond to IL-1 and GM-CSF in SLE Patients....Pages 385-387
Defect of the CTLA4-Ig Ligands on Tumor-Infiltrating Dendritic Cells....Pages 389-392
Mixed Epidermal Cell Lymphocyte Reaction: HLA-DR + Cells Exhibit a Greater Immunostimulatory Activity than CD1a + Cells....Pages 393-396
Human Dendritic Cells Enhance Growth and Differentiation of CD40 Activated B Cells....Pages 397-399
Human Dendritic Cells Can Drive CD40-Activated slgD+ B Cells to Mount Mucosal-Type Humoral Response....Pages 401-403
Factors Affecting Spontaneous Dendritic Cell-Lymphocyte Clustering in Skin Afferent Lymph....Pages 405-407
Characteristics of Antigen-Independent and Antigen-Dependent Interaction of Dendritic Cells with CD4+T Cells....Pages 409-411
Priming of T Cells with Dendritic, Macrophage and B Cell Lines in Vivo Requires More than Surface Expression of MHC II and B7 Molecules - Possible Role of CD44 and Integrins....Pages 413-417
Identification of Novel cDNAs Derived from Human Lung Dendritic Cells Using a Subtractive Cloning Approach....Pages 419-422
Mechanisms of Retrovirally Induced Immunosuppression Acting via Dendritic Cells....Pages 423-427
Preferential Entry and Productive Infection of CD4 Expressing Lymphoid Dendritic Cells by Macrophage-Tropic HIV-1....Pages 429-433
Expression of Cytokine mRNA by Human Peripheral Blood Dendritic Cells Stimulated with Human Immunodeficiency Virus and Herpes Simplex Virus....Pages 435-437
Splenic Interdigitating Dendritic Cells in Humans: Characterization and HIV Infection Frequency in Vivo ....Pages 439-441
HIV Infection of Blood Dendritic Cells in Vitro and in Vivo....Pages 443-445
In Vivo and in Vitro Infection of Human Langerhans Cells by HIV-1....Pages 447-451
In Vitro Infection of Human Epidermal Langerhans Cells with Human Immunodeficiency Virus Type 1....Pages 453-455
Dendritic Cell-T Cell Conjugates that Migrate from Normal Human Skin are an Explosive Site of Infection for HIV-1....Pages 457-460
Cell-Cell Interactions Regulate Dendritic Cell-Dependent HIV-1 Production in CD4 + T Lymphocytes....Pages 461-463
In Vitro HIV-1 Infection of Isolated Epidermal Langerhans Cells with a Cell-Free System....Pages 465-468
Defects in the Function of Dendritic Cells in Murine Retroviral Infection....Pages 469-472
Human Epidermal Langerhans Cells Efficiently Present HIV-1 Antigens to Specific T Cell Lines....Pages 473-475
Infection of Cultured Immature Dendritic Cells with Human Immunodeficiency Virus Type 1....Pages 477-479
Discontinuous Distribution of HIV-1 Quasispecies in Epidermal Langerhans Cells of an AIDS Patient and Evidence for Double Infection....Pages 481-483
Conditional Ablation of Dendritic Cells in Mice: Comparison of Two Animal Models....Pages 485-487
Activation of an HIV-LTR-CAT Transgene in Murine Macrophages by Interferon-γ in Synergism with other Cytokines or Endotoxin....Pages 489-492
Dendritic Cells, Apoptosis and Murine Retrovirus....Pages 493-496
Early Events in Contact Sensitivity....Pages 497-500
Dendritic Cells Can Be Used as Physiological Adjuvant in Vivo....Pages 501-505
Dendritic Cells Seclude Leishmania Parasites that Persist in Cured Mice — A Role in the Maintenance of T-Cell Memory?....Pages 507-509
Exposure to Type-I Collagen Induces Maturation of Mouse Liver Dendritic Cell Progenitors....Pages 511-518
Human Keratinocyte-Derived IL-12 Affects LC-Induced Allogeneic T-Cell Responses....Pages 519-521
Studies on Langerhans Cell Phenotype in Human Afferent Skin Lymph from Allergic Contact Dermatitis....Pages 523-525
Rosettes of Langerhans Cells and Activated T Cells in Human Skin Lymph Derived from Irritant Contact Dermatitis....Pages 527-529
Migration of Interleukin-6 Producing Langerhans Cells to Draining Lymph Nodes following Skin Sensitization....Pages 531-533
The Role of Cytokines in the Pathogenesis of Pulmonary Langerhans’ Cell Histiocytosis....Pages 535-537
Importance of HLA-DR+ and CD1a+ Epidermal Cells for Cytokine Production in Psoriasis....Pages 539-541
Isolation of Dendritic Leukocytes from Mouse Liver....Pages 543-548
Electronmicroscopic Study of Canine Cutaneous Histiocytoma : A Benign Langerhans Cell Tumor....Pages 549-551
Isolation and Characteristics of Dendritic Cell Progenitors from the Bone Marrow of the Hodgkin’s Disease Patients....Pages 553-555
Defective Dendritic Cell (DC) Function in a HLA-B27 Transgenic Rat Model of Spondyloarthropathy (SpA)....Pages 557-559
Improved Isolation of Dendritic Cells in Chronic Arthritic Joints Reveals No B7 (CD80) Surface Expression....Pages 561-563
Vaccine Adjuvancy: A New Potential Area of Development for GM-CSF....Pages 565-569
Back Matter....Pages 571-572