Deep Brain Stimulation and Epilepsy

Cover......Page 1
Title Page......Page 2
Copyright Page......Page 3
Table of Contents......Page 4
Contributors......Page 8
I Historical overview: brain stimulation and epilepsy......Page 14
 1 Brain stimulation and epilepsy: basic overview and novel approaches......Page 16
II Pathogenesis of brain stimulation: animal studies......Page 32
 2 The basal ganglia: an overview......Page 34
 3 The subthalamic nucleus: anatomy and neurophysiology......Page 42
 4 Brain stimulation and epilepsy: electrical stimulus characteristics......Page 58
 5 Electrically excitable nerve elements: excitation sites in peripheral and central stimulation......Page 68
 6 Control of neuronal activity by electrical fields: in vitro models of epilepsy......Page 80
 7 The nigral control of epilepsy: basal ganglia circuitry as a substrate for seizure control......Page 100
 8 High frequency direct cortical electrical stimulation: an animal model of induced acute focal seizures......Page 110
III Pathogenesis of brain stimulation: human studies......Page 116
 9 Cortico-coritcal evoked potentials......Page 118
 10 Repetitive transcranial magnetic stimulation......Page 126
 11 High frequency subthalamic nucleus stimulation......Page 142
 12 Cortical-evoked potentials from deep brain stimulation......Page 156
 13 EEG recording from the subthalamic nucleus in patients with epilepsy......Page 170
 14 EEG and the anterior thalamic nucleus......Page 184
IV Effect of brain stimulation on epileptic seizures: animal experiments......Page 200
 15 Absence seizures in the GAERS model: subthalamic nucleus stimulation......Page 202
 16 Focal limbic seizures induced by kainic acid: effects of bilateral subthalamic nucleus stimulation......Page 212
 17 Focal stimulation versus deep brain stimulation......Page 222
 18 The anterior thalamus and the pentylenetetrazol (PTZ) model......Page 228
V Effect of brain stimulation on epileptic seizures: human studies......Page 258
 19 Vagal nerve stimulation: surgical technique......Page 260
 20 Vagal nerve stimulation: effects on seizures......Page 268
 21 Therapeutic prospects and safety of transcranial magnetic stimulation in epilepsy......Page 276
 22 Direct cortical electrical stimulation in the treatment of epilepsy......Page 288
 23 Electrical neuromodulation of the epileptic focus in cases of temporal lobe seizures......Page 298
 24 Anterior thalamic nucleus stimulation: surgical procedure......Page 312
 25 Anterior thalamic nucleus stimulation: issues in study design......Page 318
 26 Surgical procedure for subthalamic nucleus stimulation......Page 334
 27 Subthalamic nucleus and substantia nigra pars reticulata stimulation: the Grenoble experience......Page 348
 28 Subthalamic nucleus stimulation in patients with intractable epilepsy: the Cleveland experience......Page 362
VI Brain stimulation: future prospects......Page 370
 29 The future of brain stimulation for seizure control......Page 372
Index......Page 376