Cytotoxic Effector Mechanisms

Front Matter....Pages I-VII
Granule-Mediated Cytolysis of Target Cells....Pages 1-9
Structure and Function of Perforin....Pages 11-17
Structure and Function of C8 in the Membrane Attack Sequence of Complement....Pages 19-31
Granzymes: a Family of Serine Proteases in Granules of Cytolytic T Lymphocytes....Pages 33-47
The Molecular Mechanism of Complement C9 Insertion and Polymerisation in Biological Membranes....Pages 49-65
The Isolation and Characterization of Two Cytotoxic T-Lymphocyte-Specific Serine Protease Genes....Pages 67-80
A Serine Protease-Encoding Gene That Marks Activated Cytotoxic T Cells In Vivo and In Vitro....Pages 81-92
Structure and Function of the Family of Proteoglycans That Reside in the Secretory Granules of Natural Killer Cells and Other Effector Cells of the Immune Response....Pages 93-108
The Homologous Species Restriction of the Complement Attack: Structure and Function of the C8 Binding Protein....Pages 109-118
Back Matter....Pages 119-120