Cytochrome Systems: Molecular Biology and Bioenergetics

Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Cytochrome Systems: From Discovery to Present Developments....Pages 3-11
Front Matter....Pages 13-13
Genetics of E. Coli Cytochromes which are Components of the Aerobic Respiratory Chain....Pages 15-22
Molecular Genetic Approaches to Studying the Structure and Function of the Cytochrome c 2 and the Cytochrome bc 1 Complex from Rhodobacter Capsulatus ....Pages 23-34
Structural Homologies in the Cytochrome B/C 1 Complex from Rhodobacter ....Pages 35-40
Genes and Sequences for Subunits of Respiratory Complexes in Paracoccus denitrificans ....Pages 41-47
Organization and Expression of Nuclear Genes for Yeast Cytochrome c Oxidase....Pages 49-56
The cDna and a Structural Gene for Rat Liver Cytochrome C Oxidase Subunit VIc....Pages 57-65
Genetics of Yeast Coenzyme QH 2 -Cytochrome C Reductase....Pages 67-77
Sequence Analysis of Mammalian Cytochrome b Mutants....Pages 79-86
Plant Mitochondrial Genes, Cytochrome C Oxidase and Cytoplasmic Male Sterility....Pages 87-95
A Mutation Affecting Lariat Formation, but not Splicing of a Yeast Mitochondrial Group II Intron....Pages 97-102
The Evolution of Mitochondrially Coded Cytochrome Genes: A Quantitative Estimate....Pages 103-109
Involvement of Nuclear Genes in Splicing of the Mitochondrial COB Transcript in S. Cerevisiae....Pages 111-117
Introns as Key Elements in the Evolution of Mitochondrial Genomes in Lower Eukaryotes....Pages 119-127
Front Matter....Pages 129-129
Core Protein Deficiency in Complex III of the Respiratory Chain, in a Missence Exonic Mitochondrial Yeast Mutant of Cytochrome B Gene....Pages 131-132
Localization and Partial Sequencing Analysis of Mitochondrial Gene for Apocytochrome B in Sunflower....Pages 133-134
Molecular Basis for Resistance to Inhibitors of the Mitochondrial Ubiquinol-Cytochrome c Reductase in Saccharomyces cerevisiae ....Pages 135-136
Structure of the Proteins and Genes for the Nuclear-Encoded Subunits of N. Crassa Cytochrome Oxidase....Pages 137-138
Partial Sequence of Gene for Cytochrome Oxydase Subunit II of Sunflower Mitochondrial DNA....Pages 139-140
Unusual Features of Kinetoplast DNA from Trypanosomes: Novel Mechanism of Gene Expression (RNA-Editing), The Absence of tRNA Genes and the Variable Presence of a Cytochrome Oxidase Subunit Gene....Pages 141-142
Front Matter....Pages 143-143
Heterogeneous Efficiencies of mRNA Translation in Human Mitochondria....Pages 145-152
Regulation of the Expression of COI and COIII mRNAs in Rat Liver Mitochondria....Pages 153-159
Two Consensus Sequences for RNA Processing in Neurospora crassa Mitochondria....Pages 161-168
Primary Structure of the Yeast Nuclear CBS1 Gene Product, Necessary to Activate Translation of Mitochondrial COB mRNA....Pages 169-176
A Calmodulin-Like Protein in the Cytochrome bc 1 Complex Required for Synthesis of both Cytochrome bc 1 and Cytochrome c Oxidase Complexes in Yeast Mitochondria....Pages 177-187
Import of Cytochromes b 2 and c 1 into Mitochondria is Dependent on Both Membrane Potential and Nucleoside Triphosphates....Pages 189-196
NADH: A Common Requirement for the Import and Maturation of Cytochromes c and c 1 ....Pages 197-208
Import of Proteins into Mitochondria: Structural and Functional Role of the Prepeptide....Pages 209-214
Interaction of the Mitochondrial Precursor Protein Apocytochrome C with Model Membranes and its Implications for Protein Translocation....Pages 215-223
Influence of Thyroid Hormones on the Expression of Nuclear Genes Encoding Subunits of the Cytochrome bc 1 Complex....Pages 225-231
Front Matter....Pages 233-233
Import of Cytochrome c 1 and Cytochrome b 2 into Mitochondria....Pages 235-236
Front Matter....Pages 237-237
Cytochrome C Oxidase: Past, Present and Future....Pages 239-246
Universal Features in Cytochrome Oxidase....Pages 247-252
Polypeptide Subunits Encoded by Nuclear Genes are Essential Components of Eukaryotic Cytochrome C Oxidase....Pages 253-260
Respiratory Complex IV and Cytochrome a,a 3 ....Pages 261-270
An Amino Acid Sequence Region of Subunit II of Cytochrome Oxidase which may be Responsible for Evolutionary Changes in Reactivity with Different Cytochromes c ....Pages 271-279
Evidence for a Functional Role of Nuclear Encoded Subunits in Mitochondrial Cytochrome c Oxidase....Pages 281-288
Structural Analysis of the BC 1 Complex from Beef Heart Mitochondria by the Sided Hydropathy Plot and by Comparison with other BC Complexes....Pages 289-301
Crystallisation of Water-Soluble Preparations of the Iron-Sulfur-Protein and Cytochrome C 1 of Ubiquinol:Cytochrome Reductase from Neurospora Mitochondria....Pages 303-308
Iron Cluster Sites of Cardiac Ip-Subunit of Succinate Dehydrogenase....Pages 309-314
Front Matter....Pages 237-237
Polypeptides in Mitochondrial Electron-Transfer Complexes....Pages 315-324
The Fatty Acid-Anchored Four Heme Cytochrome of the Photosynthetic Reaction Center from the Purple Bacterium Rhodopseudomonas Viridis ....Pages 325-331
Front Matter....Pages 333-333
Membrane Protein in Paracoccus Denitrificans Resembles Subunit III of Beef Heart Cytochrome Oxidase....Pages 335-336
The Circular Dichroism Properties of the Rieske Protein and the b and c 1 Cytochromes of the Mitochondrial bc 1 Complex....Pages 337-338
Monomerization of Cytochrome Oxidase might be Essential for Subunit III Removal....Pages 339-340
Fourier-Transform Infra-Red Studies of Cytochrome c Oxidase....Pages 341-342
Isoenzymes of Human Cytochrome c Oxidase....Pages 343-344
Folding of Integral Membrane Proteins: Renaturation Experiments with Bacteriorhodopsin Support a Two-Stage Mechanism....Pages 345-346
Front Matter....Pages 347-347
The Nature of Ferryl, Fe(IV)=0, Haem in Peroxidases....Pages 349-360
Polarization in Heme Proteins and Cytochrome C Oxidase....Pages 361-369
Effects of Freezing on the Coordination State and Ligand Orientation in Hemoproteins....Pages 371-375
Catalytic Mechanism of O 2 Reduction by Cytochrome Oxidase....Pages 377-383
The Electron-Transfer Reactions in and Substrate Binding to Cytochrome C Oxidase....Pages 385-390
Control of Cytochrome Oxidase in Proteoliposomes: Flux And Stoichiometry....Pages 391-398
Cytochrome C Oxidase Activity is Regulated by Nucleotides and Anions....Pages 399-406
Cytochrome Oxidase and Neuromuscular Diseases....Pages 407-413
Electron Transfer between Cardiac Cytochrome c 1 and c ....Pages 415-422
Heme Cluster Structures and Electron Transfer in Multiheme Cytochromes C3....Pages 423-430
Front Matter....Pages 431-431
Electron Exchange Between Cytochromes a ....Pages 433-434
Pulsed, Resting and Peroxy Forms of Cytochrome Oxidase....Pages 435-436
Front Matter....Pages 431-431
Effect of pH and Temperature on Electron Transfer in Mixed-Valence Cytochrome c Oxidase....Pages 437-438
The pH-Dependence of the Reductional Levels of Cytochrome c and Cytochrome a During Turnover of Cytochrome c Oxidase....Pages 439-440
Front Matter....Pages 441-441
Studies of Bacterial NADH-Ubiquinone (or Menaquinone) Oxidoreductase Systems....Pages 443-450
Localized Valence States in Iron-Sulfur Clusters and Their Possible Relationship to the Ability of Iron-Sulfur Clusters to Catalyze Reactions other than Electron Transfer....Pages 451-458
Probing the Fe/S Domain with EPR: Pandora’s Box Ajar....Pages 459-466
Aspects of Spin Coupling Between Even and Odd Electron Systems: Applications To Succinate: Q Reductase....Pages 467-471
The Iron-Sulfur Clusters in Succinate Dehydrogenase....Pages 473-484
Mechanisms of Electron Transfer in Succinate Dehydrogenase and Fumarate Reductase: Possible Functions for Iron-Sulphur Centre 2 and Cytochrome b ....Pages 485-491
Front Matter....Pages 493-493
Structural and Mechanistic Aspects of the Quinone Binding Sites of the bc Complexes....Pages 495-502
QP-S — The Electron Acceptor of Succinate Dehydrogenase....Pages 503-508
Characteristics of QP-C and Reconstitution of the QH 2 -CYT C Reductase....Pages 509-516
The Kinetics of Oxidation of Cytochrome B are in Agreement with the Q-Cycle Hypothesis....Pages 517-522
The Q-Reaction Domains of Mitochondrial QH 2 :Cytochrome C Oxidoreductase....Pages 523-531
EPR Studies of the Quinone Reaction Sites in Bacteria....Pages 533-540
EPR Signal II in Photosystem II : Redox and Paramagnetic Interactions with the O 2 Evolving Enzyme....Pages 541-547
Studies on the Ubiquinone Pool in Mitochondrial Electron Transfer....Pages 549-556
Front Matter....Pages 557-557
Effects of Proteolytic Digestion and Chemical Modification of b-c 1 Complex on the Fe-S Center and the Stable Ubisemiquinone (SQ c )....Pages 559-560
Kinetics of Ubiquinol Cytochrome c Reductase: Lack of a Diffusion-Limited Step with Short Chain Ubiquinols as Substrates....Pages 561-562
Front Matter....Pages 563-563
Biochemistry and Molecular Biology of the Escherichia Coli Aerobic Respiratory Chain....Pages 565-574
The Interplay Between Photosynthesis and Respiration in Facultative Anoxygenic Phototrophic Bacteria....Pages 575-583
Front Matter....Pages 563-563
The Ubiquinol-Cytochrome C Oxidoreductase of Phototrophic Bacteria....Pages 585-592
The Redox Reaction Between Cytochrome b H and the Semiquinone-Quinol Couple of Q c is Electrogenic in Ubiquinolcyt c 2 Oxidoreductase....Pages 593-600
Construction and Characterization of Monolayer Films of the Reaction Center Cytochrome- C Protein From Rhodopseudomonas Viridis ....Pages 601-608
Structure-Function Relationships in the Rhodopseudomonas viridis Reaction Center Complex: Electrogenic Steps Contributing to Δψ Formation....Pages 609-616
Catalytic Sites for Reduction and Oxidation of Quinones....Pages 617-624
Studies of the Electrogenicity of the Reduction of Cytochrome b 561 : Through the Antimycin-Sensitive Site of the Ubiquinol-Cytochrome c 2 Oxidoreductase Complex of Rhodobacter Sphaeroides ....Pages 625-631
Mutants Affecting the Quinol Oxidation Site of Ubiquinolcyt c 2 -Oxidoreductase....Pages 633-640
Cytochrome b 558 of Bacillus Subtilis ....Pages 641-647
Mitochondrial Cytochrome b 560 ....Pages 649-656
Isolation of the Photosystem Two Reaction Centre and the Location and Function of Cytochrome b-559....Pages 657-666
Front Matter....Pages 667-667
Effect of Antimycin on the Kinetics of Reduction of b and c 1 Cytochromes in Single Turnover of the Mitochondrial b-c 1 Complex....Pages 669-671
The b-Q cycle, a New Model for the Pathways of Electrons and Protons Through the bc 1 Complex. Action of Antimycin A at Center O....Pages 673-674
Rapid Oxidation Kinetics of Quinol-Cytochrome C Oxidoreductase: Quinone or Semiquinone Cycle?....Pages 675-677
Electron Conduction Between b Cytochromes of the Mitochondrial Respiratory Chain in the Presence of Antimycin Plus Myxothiazol....Pages 679-680
The Release of Nad· Radical is the Limiting Step in the Redox Reaction Between Fe(III) Cytochrome C and NADH....Pages 681-682
Properties of Cytochrome b 558 in Complex II of Ascaris Muscle Mitochondria and its Function in Anaerobic Respiration....Pages 683-685
Front Matter....Pages 687-687
Pulsed and Resting Cytochrome Oxidase: An Update of Optical and Molecular Properties....Pages 689-695
Is H 2 O 2 Involved in Electron Transport Between Cytochromes a and a 3 in Cytochrome Oxidase?....Pages 697-703
Conformational Transitions of Cytochrome c Oxidase Induced by Partial Reduction....Pages 705-712
Redox-Linked Conformational Changes in Cytochrome C Oxidase....Pages 713-720
Front Matter....Pages 721-721
Protonmotive Activity of the Cytochrome Chain of Mitochondria: Models and Features....Pages 723-732
The Mechanism of Electron Gating in Cytochrome c Oxidase....Pages 733-741
Proton Pump Activity in Bacterial Cytochrome Oxidases....Pages 743-750
Topography and Protonmotive Mechanism of Mitochondrial Coupling Site 2....Pages 751-765
The Q-Gated Proton Pump Model of Ubiquinol Cytochrome c Reductase: Electron and Proton Transfer Pathways and Role of Polypeptides....Pages 767-776
Photosynthetic Control and ATP/Electron Ratio in Bacterial Photophosphorylation....Pages 777-784
Front Matter....Pages 785-785
Protonmotive Activity of Mitochondrial Cytochrome c Oxidase....Pages 787-788
Back Matter....Pages 789-805