Coronaviruses

Front Matter....Pages i-xii
Coronaviruses: A Historical Perspective....Pages 1-5
Molecular Biology of Coronavirus 1986....Pages 7-13
The Complete Nucleotide Sequence of Avian Infectious Bronchitis Virus: Analysis of the Polymerase-Coding Region....Pages 15-29
Sequence and Structure of the Coronavirus Peplomer Protein....Pages 31-38
Identification of the Coronavirus MHV-JHM mRNA 4 Gene Product Using Fusion Protein Antisera....Pages 39-45
Identification of a New Gene Product Encoded by mRNA D of Infectious Bronchitis Virus....Pages 47-54
Expression of Porcine Transmissible Gastroenteritis Virus Genes in E. Coli as β-Galactosidase Chimaeric Proteins....Pages 55-64
Sequences Involved in the Replication of Coronaviruses....Pages 65-72
Murine Coronavirus 5′-End Genomic RNA Sequence Reveals Mechanism of Leader-Primed Transcription....Pages 73-81
Expression of the E1 Gene of Mouse Hepatitis Virus (MHV A59) In Vivo and In Vitro ....Pages 83-97
RNA Recombination of Coronavirus....Pages 99-107
Surface Glycoproteins of Transmissible Gastroenteritis Virus: Functions and Gene Sequence....Pages 109-116
Nucleotide Sequence of the Porcine Transmissible Gastroenteritis Coronavirus Matrix Protein Gene....Pages 117-122
Deduced Amino Acid Sequence and Potential O-Glycosylation Sites for the Bovine Coronavirus Matrix Protein....Pages 123-129
Glycosylation of the Bovine Coronavirus Hemagglutinin Protein....Pages 131-136
Studies into the Mechanism of MHV Transcription....Pages 137-149
Expression of IBV Spike Protein by a Vaccinia Virus Recombinant....Pages 151-153
Translation and Processing of MHV-A59 Virion RNA in Reticulocyte Lysates and Infected Cells....Pages 155-156
Temporal Regulation of RNA Synthesis of Bovine Coronavirus....Pages 157-158
Temperature-Sensitive Mutants of MHV-A59....Pages 159-168
Characterization of a Small Plaque Mutant of the A59 Strain of Mouse Hepatitis Virus Defective in Cell Fusion....Pages 169-174
The Role of Protease-Dependent Cell Membrane Fusion in Persistent and Lytic Infections of Murine Hepatitis Virus....Pages 175-186
Defective Interfering Particles of Coronavirus....Pages 187-195
Identification of a Receptor for Mouse Hepatitis Virus....Pages 197-202
Analysis and Pathogenetic Significance of Class II MHC (Ia) Antigen Induction on Astrocytes During JHM Coronavirus Infection in Rats....Pages 203-217
Expression of MHC Class I Genes in Mouse Hepatitis Virus (MHV-A59) Infection and in Multiple Sclerosis....Pages 219-222
 In Vivo and In Vitro Models of Demyelinating Diseases, XX: Replication of Coronaviruses in Primary Neural Cultures from Genetically Resistant and Susceptible Mice....Pages 223-230
Differential Effects of MHV-4 Infection of Astrocytes and Oligodendrocytes in Vitro....Pages 231-237
 In Vivo and In Vitro Models of Demyelinating Disease XXI: Relationship Between Differentiation of RAT Oligodendrocytes and Control of JHMV Replication....Pages 239-254
Characterization of a Non-Pathogenic MHV3 Variant Derived from a Persistently Infected Lymphoid Cell Line....Pages 255-263
Are Differences in Biological Properties of MHV Associated with Differences in Specific Regions of their Nucleocapsid mRNA?....Pages 265-266
Influence of the Cell Cycle on the Infectious Titer of Murine Hepatitis Virus, Strain A59....Pages 267-268
Characterization of Temperature-Sensitive Mutants Mouse Hepatitis Virus Type 3....Pages 269-270
A Cell Line Defective in Murine Coronavirus Internalization....Pages 271-272
Regulation of Persistent Infections with Human Coronavirus OC43....Pages 273-274
Development of Rapid Assay for Screening Compounds for Antiviral Activity Against RNA Viruses....Pages 275-276
Biology of Coronaviruses 1986....Pages 277-286
Molecular Determinants of CNS Virulence of MHV-4....Pages 287-295
Maternal Antibody-Modulated MHV-JHM Infection in C57BL/6 and BALB/c Mice....Pages 297-305
Coronavirus JHM Induced Demyelinating Disease: Specific Domains on the E2-Protein are Associated with Neurovirulence....Pages 307-320
Increased Hepatotropism of Mutants of MHV, Strain JHM, Selected with Monoclonal Antibodies....Pages 321-331
Pathogenic Characteristics of Neutralization-Resistant Variants of JHM Coronavirus (MHV-4)....Pages 333-342
Characterization of JHMV Variants Isolated from RAT Brain and Cultured Neural Cells after Wild Type JHMV Infection....Pages 343-349
Critical Epitopes in Transmissible Gastroenteritis Virus Neutralization....Pages 351-363
Protective Effect of the F(ab′) 2 Fragments of Monoclonal Antibodies to Mouse Hepatitis Virus....Pages 365-371
Intrathecal Humoral Immune Response in Corona Virus Induced Encephalo-Myelitis of Lewis and BN Rats....Pages 373-381
 In Vivo and In Vitro Models of Demyelinating Disease, XXIII: Infection by JHM Virus of Athymic Rats....Pages 383-390
Characterization of Mouse Hepatitis Virus-Reactive T Cell Clones....Pages 391-398
Immune Mediated Clearance of JHM Virus from the Central Nervous System....Pages 399-410
Susceptibility to Mouse Hepatitis Virus Strain 3 in Balb/cJ Mice: Failure of Immune Cell Proliferation and Interleukin 2 Production....Pages 411-420
Coronavirus and Multiple Sclerosis: Results of a Case/Control Longitudinal Serological Study....Pages 421-429
Selective Tropism of MHV3 for CNS Cells and Consequences of MHV3 Infection on CNS Cells Activities....Pages 431-437
Neuropathogenicity of Mutant Strains of Mouse Hepatitis Virus, 1a and 2c, from DBT Cells Persistently Infected with JHM Strain....Pages 439-440
Coronavirus SD-Induced Immunoregulatory Disturbances in a Murine Model of Demyelination....Pages 441-447
Intranasal Challenge Immunity of Mice to Antigenically Homologous and Heterologous Strains of Mouse Hepatitis Virus....Pages 449-450
Infection and Involution of Mouse Thymus by MHV-4....Pages 451-453
Genetically-Determined Sensitivity to MHV3 Infections is Expressed in Vitro in Lymphoid Cells and Macrophages....Pages 455-463
Prostaglandin E2 (PGE2) Alters the Pathogenesis of MHV-3 Infection in Susceptible Balb/cJ Mice....Pages 465-466
Effect of Cyclosporin A on MHV3-Induced Chronic CNS Infection in Mice....Pages 467-468
Resistance to Murine Hepatitis Virus Strain 3 (MHV-3) Infection in A/J Mice is not Affected by Cyclosporin A (CSA)....Pages 469-471
Monoclonal Antibodies to Two Bovine Coronavirus Glycoproteins Neutralize Virus Infectivity....Pages 473-474
Antibody Response in Swine to Individual Transmissible Gastroenteritis Virus (TGEV) Proteins....Pages 475-481
The Neutralization Epitopes on the Spike Protein of Infectious Bronchitis Virus and their Antigenic Variation....Pages 483-492
Complement-Dependent Neutralization of Transmissible Gastroenteritis Virus by Monoclonal Antibodies....Pages 493-500
Properties of Coronavirus IBV After Removal of the S1 Subunit of the Spike Glycoprotein....Pages 501-507
Identification of Epitopes of Immunological Importance on the Peplomer of Porcine Transmissible Gastroenteritis Virus....Pages 509-515
Characterization of Monoclonal Antibodies to Human OC43....Pages 517-520
Relatedness of Rabbit Coronavirus to Other Coronaviruses....Pages 521-527
Virologic and Immunologic Aspects of Feline Infectious Peritonitis Virus Infection....Pages 529-550
Stratagies for a Successful Coronavirus (TGE) Vaccine for Swine....Pages 551-557
Humoral Immune Response of Cats to Virulent and Avirulent Feline Infectious Peritonitis Virus Isolates....Pages 559-568
Immunization Against Feline Coronaviruses....Pages 569-576
Serodiagnosis of Feline Infectious Peritonitis....Pages 577-578
An Eight-Year Study of the Viral Agents of Acute Gastroenteritis in Humans: Ultrastructural Observations and Seasonal Distribution with A Major Emphasis on Coronavirus-like Particles....Pages 579-581
Back Matter....Pages 583-591