Contraception Research for Today and the Nineties: Progress in Birth Control Vaccines

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Demographic Trends, Global and Indian Scene, and Implications....Pages 3-8
Population Control: Strategies and Experience....Pages 9-16
WHO Special Programme in Human Reproduction and Contraceptive Needs of Developing Countries....Pages 17-26
Front Matter....Pages 27-27
Steroid Implants for Long-Term Contraception....Pages 29-35
The Levonorgestrel-Releasing IUD....Pages 37-48
Antiprogestin Ru 486: A Contragestive Agent....Pages 49-66
Vaginal Pills: Systemic Contraception Induced by Vaginal Administration of Contraceptive Pills....Pages 67-79
Front Matter....Pages 81-81
Neuroendocrine Regulation of Fertility....Pages 83-91
GnRH Analogs in Contraception....Pages 93-100
A Novel Hypothalamic Peptide Inhibitor of Prolactin Secretion....Pages 101-113
Inhibin: Chemistry, Measurement, Physiology, and Its Potential as a Fertility-Regulating Agent....Pages 115-129
Front Matter....Pages 131-131
Immunobiology of Human Trophoblast....Pages 133-142
Maternal-Placental Interactions in Early Human Pregnancy....Pages 143-149
Maternal-Blastocyst Interaction at Implantation....Pages 151-160
Immunogenetic Control of Pregnancy and Development....Pages 161-169
Cell-Mediated Immune Mechanisms in Recurrent Spontaneous Abortion....Pages 171-180
Front Matter....Pages 181-181
Birth Control Vaccines Inducing Antibodies Against Chorionic Gonadotropin....Pages 183-197
Cloning and Expression of Gonadotropin Hormone Genes....Pages 199-206
Hormonal Regulation of Pituitary Gonadotropin Gene Expression....Pages 207-215
Active Immunization of Rhesus Monkeys Against the β-Subunit of Ovine Luteinizing Hormone: Evaluation of Safety and Effectiveness of an Antigonadotropin Vaccine....Pages 217-230
Front Matter....Pages 181-181
Safety Evaluation of HCG Vaccine in Primates: Autoantibody Production....Pages 231-239
Potential of LH Receptor as an Immunocontraceptive Vaccine: Studies in the Baboon (Papio)....Pages 241-252
Development of a Contraceptive Vaccine for Use by the Human Male: Results of a Feasibility Study Carried Out in Adult Male Bonnet Monkeys ( Macaca radiata )....Pages 253-258
Front Matter....Pages 259-259
Hormonal and Cellular Control of Seminiferous Tubular Function....Pages 261-276
LDH-C 4 as the Model Sperm Antigen for a Contraceptive Vaccine....Pages 277-283
Should Cell-Mediated Immunity be Considered in the Implementation of Antifertility Vaccines?....Pages 285-291
Contraceptive Potential of Secretory Immunity....Pages 293-302
Establishment of Human-Mouse Hybridoma to Human Seminal Plasma Antigen and Its Contribution to a Contraceptive Vaccine....Pages 303-314
An Immunoreactive Human Sperm Antigen in Rat Spermatogenic Cells....Pages 315-322
Role of the Fertilization Antigen (FA-1) in Immunoregulation of Fertility and Involuntary Infertility in Humans....Pages 323-339
Origin of Zona Pellucida Antigens and Its Relevance to the Development of Contraceptive Vaccine....Pages 341-343
Disillusions and Hopes About Zona Pellucida Glycoproteins....Pages 345-356
Front Matter....Pages 357-357
New Developments in Epitope Analysis....Pages 359-367
Immunological Difficulties and Requirements for Immune Manipulations in the Field of Reproduction....Pages 369-384
The Past Is Prologue: Implications of the Symposium....Pages 385-388
Back Matter....Pages 389-401