Concepts in Viral Pathogenesis II

Front Matter....Pages i-xix
Front Matter....Pages 1-1
The Three-dimensional Structure of Poliovirus: Implications for Virus Evolution, Assembly, and Immune Recognition....Pages 3-14
The Three-dimensional Structure of Surface Antigens from Animal Viruses....Pages 15-24
Using Nucleotide Sequence Determination to Understand Viruses....Pages 25-31
Viruses with Ambisense RNA Genomes....Pages 32-39
Human Respiratory Syncytial Virus Genome and Gene Products....Pages 40-46
Front Matter....Pages 47-47
Bovine Papillomavirus DNA Vectors....Pages 49-56
Genetic Engineering of Vaccinia Virus Vectors: Development of Live Recombinant Vaccines....Pages 57-60
Viral Enhancer Elements....Pages 61-67
Front Matter....Pages 69-69
Amplification of Proto-oncogenes in Tumorigenesis....Pages 71-78
Multistep Scenarios in Tumor Development and the Role of Oncogene Activation by Chromosomal Translocations....Pages 79-88
Oncogene Activation by Chromosome Translocation....Pages 89-97
Oncogenes, Growth Factors, and Receptors....Pages 98-109
Specificity of Viral Gene Controlling Elements in Transgenic Mice....Pages 110-113
Front Matter....Pages 115-115
Isolation of Cellular Receptors for Viruses....Pages 117-125
Viral Receptors Serving Host Functions....Pages 126-131
Genetics of Retrovirus Tumorigenicity....Pages 132-140
Adenovirus Entry into Cells: Some New Observations on an Old Problem....Pages 141-146
Molecular Anatomy of Viral Infection: Study of Viral Nucleic Acid Sequences and Proteins in Whole Body Sections....Pages 147-156
Front Matter....Pages 157-157
Mapping Neutralization Domains of Viruses....Pages 159-173
CTL Recognition of Transfected H-2 Gene and Viral Gene Products....Pages 174-181
Front Matter....Pages 157-157
Heterogeneity of CTL Reactive Antigenic Sites on SV40 Tumor Antigen....Pages 182-186
Virus-specific HLA Class II-restricted Cytotoxic T Cells....Pages 187-192
Front Matter....Pages 193-193
Molecular Mimicry....Pages 195-202
Virus-induced Autoimmune Demyelinating Disease of the Central Nervous System....Pages 203-209
Front Matter....Pages 211-211
The Enigma of Viroid Pathogenesis....Pages 213-220
Prions Causing Scrapie and Creutzfeldt-Jakob Disease....Pages 221-231
Interferon-induced Disease....Pages 232-242
African Swine Fever Virus....Pages 243-247
Theiler’s Murine Encephalomyelitis Virus (TMEV) Infection in Mice as a Model for Multiple Sclerosis....Pages 248-254
Front Matter....Pages 255-255
Human T Cell Lymphotropic Viruses and Their Family of Diseases....Pages 257-260
Pathogenesis of Parvovirus-induced Disease in Humans....Pages 261-268
Hepatitis B Virus and Cancer....Pages 269-275
Progressive Epstein-Barr Virus Infection....Pages 276-286
Human Papillomaviruses: Why Are Some Types Carcinogenic?....Pages 287-297
Front Matter....Pages 299-299
Nucleic Acid Probes to Detect Viral Diseases....Pages 301-309
In Situ Hybridization and Covert Virus Infections....Pages 310-316
Oligonucleotide Fingerprinting in the Investigations of Outbreaks of Viral Disease....Pages 317-323
Monoclonal Antibodies as Reagents....Pages 324-330
Anti-peptide Antibodies: Some Practical Considerations....Pages 331-335
Front Matter....Pages 337-338
Eradication and Possible Reintroduction of Smallpox....Pages 339-345
Front Matter....Pages 337-338
Immunogenicity of Vaccine Products and Neutralizing Antibodies....Pages 346-353
Prospects for Development of a Vaccine Against HTLV-III Disease....Pages 354-364
Prospects for a Varicella-Zoster Vaccine....Pages 365-371
Prospects for Treatment and Prevention of Latent Herpes Simplex Virus Infection....Pages 372-379
Prospects for Improved Immunization Against Influenza....Pages 380-387
Cleavage Site Mutant As a Potential Vaccine....Pages 388-393
Prospects for a Synthetic Foot-and-Mouth Disease Vaccine....Pages 394-400
Anti-idiotype Vaccines Against Viral Infections....Pages 401-411
Chemotherapy of Lassa Virus Infection....Pages 412-416
Back Matter....Pages 417-425