Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System : Biomaterials and Tissues

 Content: Cover; Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System: Biomaterials and Tissues; Copyright; Contents; Contributor contact details; Woodhead Publishing Series in Biomaterials; Foreword; Preface; Part I Generic modelling of biomechanics and biotribology; 1 Fundamentals of computational modelling of biomechanics in the musculoskeletal system; 1.1 Computational approach and its importance; 1.2 Generic computational approach and important considerations; 1.3 Computational methods and software; 1.4 Future trends; 1.5 Sources of further information and advice 1.6 References2 Finite element modeling in the musculoskeletal system: generic overview; 2.1 The musculoskeletal (MSK) system; 2.2 Overview of the finite element (FE) method; 2.3 State-of-the-art FE modeling of the MSK system; 2.4 Key modeling procedures and considerations; 2.5 Challenges and future trends; 2.6 References; 3 Joint wear simulation; 3.1 Introduction; 3.2 Classification of wear; 3.3 Analytic and theoretical modelling of wear; 3.4 Implementation of wear modelling in the assessment of joint replacement; 3.5 Validating wear models; 3.6 Future trends; 3.7 References 3.8 Appendix: useful tablesPart II Computational modelling of musculoskeletal cells and tissues; 4 Computational modeling of cell mechanics; 4.1 Introduction; 4.2 Mechanobiology of cells; 4.3 Computational descriptions of whole-cell mechanics; 4.4 Liquid drop models; 4.5 Solid elastic models; 4.6 Power-law rheology model; 4.7 Biphasic model; 4.8 Tensegrity model; 4.9 Semi-flexible chain model; 4.10 Dipole polymerization model; 4.11 Brownian ratchet models; 4.12 Dynamic stochastic model; 4.13 Constrained mixture model; 4.14 Bio-chemo-mechanical model; 4.15 Computational models for muscle cells 4.16 Future trends4.17 References; 5 Computational modeling of soft tissues and ligaments; 5.1 Introduction; 5.2 Background and preparatory results; 5.3 Multiscale modeling of unidirectional soft tissues; 5.4 Multiscale modeling of multidirectional soft tissues; 5.5 Mechanics at cellular scale: a submodeling approach; 5.6 Limitations and conclusions; 5.7 Acknowledgments; 5.8 References; 6 Computational modeling of muscle biomechanics; 6.1 Introduction; 6.2 Mechanisms of muscle contraction: muscle structure and force production; 6.3 Biophysical aspects of skeletal muscle contraction 6.4 One-dimensional skeletal muscle modeling6.5 Causes and models of history-dependence of muscle force production; 6.6 Three-dimensional skeletal muscle modeling; 6.7 References; 7 Computational modelling of articular cartilage; 7.1 Introduction; 7.2 Current state in modelling of articular cartilage; 7.3 Comparison and discussion of major theories; 7.4 Applications and challenges; 7.5 Conclusion; 7.6 References; 8 Computational modeling of bone and bone remodeling; 8.1 Introduction; 8.2 Computational modeling examples of bone mechanical properties and bone remodeling
 Abstract:             Modelling is an important aspect of the design process for biomaterials and medical devices. By effectively modelling biomaterials and implants before their implantation, it is now possible to predict certain implant-tissue reactions, degradation and wear. Consequently, computational modelling is becoming increasingly important in the design and manufacture of biomedical materials, allowing scientists to more accurately tailor their materials' properties for the in vivo environment. Computational modelling of biomechanics and biotribology in the musculoskeletal system begins with an introducti