Comparative Veterinary Pharmacology, Toxicology and Theraphy: Proceedings of the 3rd Congress of the European Association for Veterinary Pharmacology and Toxicology, August 25–29 1985, Ghent, Belgium Part II, Invited Lectures

Front Matter....Pages i-xxxvii
Front Matter....Pages 1-1
Influence of halothane anaesthesia, after xylazine premedication, on serum calcium concentration in the horse....Pages 3-12
Pharmacological properties of benzodiazepines in animals....Pages 13-23
Effects of halogenated inhalational anaesthetics on respiration in dogs....Pages 25-32
Analgesic activity of butorphanol in horses: dosage titration and clinical studies....Pages 33-44
Front Matter....Pages 45-45
Postgraduate training in the veterinary pharmacology....Pages 47-55
The teaching of veterinary pharmacology and toxicology....Pages 57-66
Front Matter....Pages 67-67
Design and evaluation of studies on drug delivery systems....Pages 69-73
Potential of new drug delivery systems in veterinary medicine....Pages 75-84
Influence of injection site on the depot effect of procaine penicillin in dogs....Pages 85-91
Influence of food on absorption of antimicrobial drugs....Pages 93-104
Front Matter....Pages 105-105
Pharmacology of the (fore)-stomach smooth muscles....Pages 107-121
Smooth muscle pharmacology of the large intestine....Pages 123-132
Recent advances in the pharmacological control of the intestinal and colonic motor profiles....Pages 133-141
Cholinergic-like effect of the H 2 -receptor antagonist ranitidine on the rabbit small intestine....Pages 143-151
Front Matter....Pages 153-153
Comparative pharmacokinetics: introductory remarks....Pages 155-160
Comparative neonatal pharmacokinetics....Pages 161-171
Comparative pharmacokinetic studies of sulphonamides....Pages 173-185
Species differences in protein binding....Pages 187-195
Front Matter....Pages 197-197
The target animal species in drug toxicity studies: an evaluation of its usefulness and limitations....Pages 199-208
The use of pharmacokinetics in chronic toxicity testing....Pages 209-223
Front Matter....Pages 197-197
The Food Animal Residue Avoidance Databank (FARAD): a computer databank of the pharmacokinetics of drugs, pesticides and environmental chemicals in food animals....Pages 225-231
Front Matter....Pages 233-233
Modulation of autonomic receptor function by Haemophilus influenzae in the respiratory system....Pages 235-244
Impairment of pulmonary homeostatic and antimicrobial defence mechanisms by infectious bovine rhinotracheitis and parainfluenza-3 virus infections....Pages 245-252
The potential of biological response modifiers in the treatment of malignancies in animals and man....Pages 253-262
Immunological defence mechanisms as a target for antibiotics....Pages 263-282
Front Matter....Pages 283-283
Comparative aspects of drug conjugation in laboratory animals, exotic species and man....Pages 285-294
Hepatic microsomes as models for comparative metabolism in vivo....Pages 295-299
Pharmacokinetics, hydroxylation and acetylation of sulphadimidine in mammals, birds, fish, reptiles and molluscs....Pages 301-318
Disposition and metabolism of 14 C-mebendazole in sheep and poultry....Pages 319-327
Front Matter....Pages 329-329
Modulation of intestinal ion absorption and secretion by enterotoxins, hormones and neurotransmitters....Pages 331-344
Species and age-dependent factors governing the clinical severity of diarrhoea....Pages 345-350
Antidiarrhoeal therapy....Pages 351-363
The effects of veterinary drugs based on humic acids in the treatment of enteritis in young animals....Pages 365-370
Front Matter....Pages 371-371
Drug reactions leading to toxicity....Pages 373-380
Clinical toxicology of an antibiotic ionophore (monensin) in ponies and horses; diagnostic markers and therapeutic considerations....Pages 381-389
Mycotoxins and mycotoxicoses in Europe....Pages 391-398
Front Matter....Pages 399-399
Role of animal disease models in evaluating the efficacy of antimicrobial agents....Pages 401-406
Effects of disease states on drug binding to serum proteins....Pages 407-414
Tickborne fever: efficacy and effects on pharmacokinetics of some chemotherapeutic agents in the goat....Pages 415-426
Statistical methods for evaluation of drug efficacy in animal models....Pages 427-433
Front Matter....Pages 399-399
Pharmacology of carbadox in the pig....Pages 435-443
Front Matter....Pages 445-445
Opioid peptides and their receptors....Pages 447-453
Endorphin systems, pain and addiction....Pages 455-466
Opioid effects on gastrointestinal motor and secretory functions....Pages 467-476
Central nervous system control of feeding behaviour by some neuropeptides in sheep....Pages 477-485
Front Matter....Pages 487-487
The use in animals of drugs licensed for human use only....Pages 489-500
The use in small animal medicine of drugs licensed for human purposes....Pages 501-511
The use in animals of drugs licensed for human use: the situation in Sweden....Pages 513-520
Regulation of drug usage in veterinary medicine: the situation in Germany....Pages 521-526
Do residues of antimicrobial drugs constitute a microbiological risk for the consumer?....Pages 527-538