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ویرایش: [1st ed. 2023]
نویسندگان: Wanninayake M Tilakaratne (editor). Thomas George Kallarakkal (editor)
سری:
ISBN (شابک) : 3031244079, 9783031244070
ناشر: Springer
سال نشر: 2023
تعداد صفحات: 774
[722]
زبان: English
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود)
حجم فایل: 57 Mb
در صورت تبدیل فایل کتاب Clinicopathological Correlation of Oral Diseases به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.
توجه داشته باشید کتاب ارتباط بالینی پاتولوژیک بیماری های دهان نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
This book represents an innovative approach to the assessment and diagnosis of both common and relatively uncommon oral diseases. It introduces the reader to adopt a systematic, analytical approach to gather clinical information and understand the underlying pathological processes to arrive at an accurate diagnosis to help efficient management of diseases in the oral and maxillofacial region. The book covers pulp and periodontal diseases, temporomandibular disorders, granulomatous disorders and salivary gland disorders. Odontogenic and non-odontogenic cysts, fibro-cemento osseous lesions, oral ulcerations, infections, tumours, reactive lesions, and oral manifestations of autoimmune and haematological disorders too are presented. High-resolution clinical radiographic and histopathological images complement the text. Additional illustrations, flow charts, and a simplified diagnostic algorithm facilitate understanding the intricate diagnostic process. Self-assessment questions in each chapter will stimulate readers’ interest. The book focuses on problem-based and case-based learning. The correlations elaborated between clinical scenarios and their pathological basis will provide both the students and practitioners with the information required to master and unravel the complexities of the diagnosis and management of oral diseases.
Foreword Preface Contents Contributors I: Introduction 1: Guide to Diagnose Oral Lesions: Principles of Clinicopathological Approach 1.1 History Taking 1.2 Clinical Examination 1.3 Investigations 1.4 Imaging 1.5 Histopathology 1.6 Exfoliative Cytology 1.7 Brush Biopsy 1.8 Molecular Tests 1.9 Haematological, Serological and Biochemical Investigations 1.10 Urinalysis 1.10.1 Skin Patch Test 1.11 Diagnostic Pathway Further Reading II: Pulp and Periodontal Diseases 2: Pain in an Upper Back Tooth: Pulpitis 2.1 Main Complaint 2.2 History of Complaint 2.3 Additional Complaints 2.4 With the Findings from History, What Is Your Differential Diagnosis? 2.5 How Do You Justify Your Differential Diagnosis After History Taking? 2.6 Findings of Examination 2.7 What Other Relevant Features You Look for with the Findings You Have so Far? 2.8 What Is Your Clinical Differential Diagnosis? 2.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 2.9.1 Cracked Tooth 2.9.2 Abfractions/Abrasions 2.9.3 Gingival Recession 2.9.4 Maxillary Sinusitis 2.10 What Is the Most Likely Diagnosis? 2.11 How Would You Investigate This Patent? 2.12 What Are the Findings of Radiography and the Importance of Radiography in the Assessment of the Teeth Prior to Treatment? 2.12.1 Interpretation of Electric Pulp Tester Results 2.13 What Is the Definitive Diagnosis? 2.14 What Are the Histopathological Features of Irreversible Pulpitis? 2.15 How Would You Manage This Patient? 2.15.1 Review and Follow-Up 2.16 Pulpitis 2.16.1 Reversible Pulpitis 2.16.2 Irreversible Pulpitis 2.16.3 Non-vital Pulp 2.16.4 Histological Classification of Pulpitis Further Reading 3: Pus Discharging from the Gum: Periodontal Disease 3.1 Main Complaint 3.2 History of Complaint 3.3 Additional Complaints 3.4 Past Dental and Medical History 3.5 Social History and Family History 3.6 Oral Hygiene Practices 3.7 With the Findings from History, What Is Your Differential Diagnosis? 3.8 How Do You Justify Your Differential Diagnosis After History Taking? 3.9 Clinical Examination 3.9.1 How Do You Assess the Periodontal Health of This Patient? 3.9.2 How Do You Interpret the BPE Codes Recorded? 3.9.3 Does This Patient Need Further Periodontal Assessment, and If So, Why? 3.9.4 What Are the Other Relevant Findings? 3.9.5 What Is Your Clinical Differential Diagnosis? 3.9.6 How Do You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 3.9.7 What Is the Most Likely Clinical Diagnosis? 3.10 Investigations 3.10.1 According to the BPE Codes Which Investigations Are Indicated? 3.10.2 How Do You Interpret the Radiographs? 3.10.3 What Are the Other Investigations That Could Be Carried Out to Aid Diagnosis? 3.10.4 What Is the Significance of High Glycaemic Levels Found in This Patient? 3.10.5 How Would You Carry Out a Systematic Multi-level Periodontal Risk Assessment on This Patient? (. Fig. 3.6) 3.10.6 What Is the Definitive Diagnosis? 3.10.7 How Did You Arrive at the Diagnosis of Periodontitis? 3.10.8 What Specific Findings Help You in Arriving at the Diagnosis? (. Table 3.3) 3.10.9 How Would You Assess the Prognosis of Teeth? 3.10.10 How Would You Manage This Patient? 3.10.11 What Is Meant by Non-surgical Debridement? 3.10.12 What Is the Importance of Achieving a Convincing Glycaemic Control? 3.10.13 How Would You Plan the Maintenance Phase for This Patient? 3.11 Periodontal Diseases and Common Conditions Affecting the Periodontium 3.11.1 Periodontal Abscess 3.11.2 Endodontic-Periodontal Lesions Further Reading III: Odontogenic and Non-Odontogenic Cysts 4: Hard Swelling in the Back of the Lower Jaw: Odontogenic Keratocyst 4.1 Main Complaint 4.2 History of Complaint 4.3 Past Dental, Medical and Social History 4.4 Clinical Examination 4.5 What Is Your Differential Diagnosis with the Findings from the History and Clinical Examination? Give a Justification for Including Different Entities 4.6 What Is the Most Likely Clinical Diagnosis? 4.7 What Are the Necessary Investigations That Should Be Carried Out in a Logical Sequence? 4.7.1 Dental Panoramic Tomography (DPT) 4.7.2 Pulp Sensibility Tests 4.7.3 Aspiration Biopsy 4.7.4 Incisional Biopsy 4.8 What Are the Histopathological Findings? 4.8.1 Histopathological Examination 4.8.2 3-D Imaging 4.9 What Is the Definitive Diagnosis? 4.10 What Specific Findings Help You to Arrive at the Diagnosis? 4.11 How Will You Treat This Patient? 4.12 What Is the Rationale for Treatment? 4.13 Follow-Up and Prognosis 4.14 Odontogenic Keratocyst Further Reading 5: Dull Pain and Discoloration of Upper Front Tooth: Radicular Cyst 5.1 Main Complaint 5.2 History of Complaint 5.3 Past Medical History 5.4 Findings of Intra-oral Examination 5.5 What Is the Most Likely Clinical Diagnosis for This Lesion? 5.6 What Investigations You Would Need to Carry Out for This Patient? 5.7 What Is the Most Likely Working Diagnosis? 5.8 How Would You Manage This Patient? 5.9 What Specific Histopathological Features Are Helpful to Arrive at a Definitive Diagnosis? 5.10 What Is the Definitive Diagnosis for This Lesion? 5.11 What Specific Findings Would Help You to Arrive at the Diagnosis of Radicular Cyst? 5.12 What Is the Prognosis for Radicular Cyst? 5.13 Radicular Cyst 5.13.1 Initiation of Cyst 5.13.2 Formation of Cyst 5.13.3 Growth and Enlargement of the Cyst Further Reading 6: Mild Pain in the Left Lower Jaw: Dentigerous Cyst 6.1 Main Complaint 6.2 History of Complaint 6.3 Past Medical History 6.4 Past Dental History 6.5 Social History 6.6 With the Findings from the History, What Is Your Differential Diagnosis and How Do You Justify Your Differential Diagnosis? 6.7 Findings of Extra-oral Examination 6.8 Findings of Intra-oral Examination 6.9 Follow-Up and Prognosis 6.10 Dentigerous Cyst 6.11 Eruption Cyst Further Reading ˘7: Lump in the Floor of the Mouth: Epidermoid/Dermoid Cyst 7.1 Main Complaint 7.2 History of Complaint 7.3 How Would You Justify Your Differential Diagnosis After History Taking? 7.4 Findings of Extra-oral Examination 7.5 Findings of Intra-oral Examination 7.6 What Are the Most Likely Clinical Diagnoses? 7.7 How Would You Investigate This Patient? 7.8 What Are the Findings of FNAC in This Patient? 7.9 What Is Your Working Diagnosis? 7.10 What Is the Treatment for This Lesion? 7.11 What Are the Macroscopic Features Seen in the Excised Lesion? 7.12 Biopsy Report Confirms That the Lesion Is an Epidermoid Cyst. What Are the Histopathological Features That Help in Arriving at the Diagnosis? 7.13 What Is the Definitive Diagnosis for This Lesion? 7.14 What Specific Findings Help You to Arrive at the Diagnosis of Epidermoid Cyst? 7.15 What Is the Prognosis of an Epidermoid Cyst? 7.16 Epidermoid/Dermoid Cyst Further Reading 8: Trauma to the Lower Lip: Mucocele 8.1 Main Complaint 8.2 History of Complaint 8.3 Additional Complaints 8.4 What Is Your Differential Diagnosis with the Findings from the History? 8.5 How Do You Justify Your Differential Diagnosis After History Taking? 8.6 Findings of Clinical Examination 8.7 What Other Relevant Features Would You Look For? 8.8 What Is Your Clinical Diagnosis? 8.9 What Is Your Justification for the Clinical Diagnosis? 8.10 How Would You Investigate This Patient? 8.11 How Would You Perform an Excisional Biopsy for This Patient? What Are the Important Considerations? 8.12 Mucocele Further Reading IV: Oral Mucosal Pigmented Lesions 9: Greyish Black Patch on the Cheek: Amalgam Tattoo 9.1 Main Complaint 9.2 History of Complaint 9.3 Past Medical History 9.4 Past Dental History 9.5 Social History 9.6 With the Findings From the History, What Is Your Differential Diagnosis? 9.7 Amalgam Tattoo 9.8 Graphite Tattoo 9.9 Melanotic Macule 9.10 Melanocytic Naevus 9.11 Hemangioma 9.12 Varix 9.13 Findings of Intra-oral Examination 9.14 What Other Relevant Features Would You Look for with the Findings You Have So Far? 9.15 What Is the Most Likely Clinical Diagnosis? 9.16 How Would You Justify Your Clinical Diagnosis? 9.17 What Investigations Need to Be Carried Out for This Patient? 9.18 What Are the Histopathological Features of the Excised Lesion? 9.19 What Is the Definitive Diagnosis for This Lesion? 9.20 What Specific Findings Help You to Arrive at the Diagnosis of Amalgam Tattoo? 9.21 What Is the Treatment for This Lesion? 9.22 What Is the Prognosis for Amalgam Tattoo? 9.23 Amalgam Tattoo Further Reading 10: A Fast-Growing Black Patch on the Upper Front Gum: Malignant Melanoma 10.1 Main Complaint 10.2 History of Complaint 10.3 Additional Complaints 10.4 With the Findings from the History, What Is Your Differential Diagnosis? 10.5 How Do You Justify Your Differential Diagnosis After History Taking? 10.6 Findings of Clinical Examination 10.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 10.8 What Is Your Clinical Differential Diagnosis? 10.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 10.9.1 Melanosis Associated with Smoking (Smoker’s Melanosis) 10.9.2 Amalgam Tattoo 10.9.3 Oral Melanotic Macule 10.9.4 Vascular Malformations 10.9.5 Kaposi Sarcoma 10.10 What Is the Most Likely Diagnosis? 10.11 How Would You Investigate This Patent? 10.12 How Would You do an Incisional Biopsy for This Patient? What Are the Important Considerations? 10.13 Biopsy Report Confirms the Previous Clinical Diagnosis of Oral Malignant Melanoma. What Are the Histopathological Features That Help in the Diagnosis? 10.14 How Would You Manage This Patient? 10.15 Oral Malignant Melanoma (OMM) Further Reading 11: A Black Spot on the Upper Gum for Many Years: Melanotic Macule 11.1 Main Complaint 11.2 History of Complaint 11.3 Additional Complaints 11.4 With the Findings from the History, What Is Your Differential Diagnosis? 11.5 How Do You Justify Your Differential Diagnosis After a History Taking? 11.6 Findings of Clinical Examination 11.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 11.8 What Is Your Clinical Diagnosis? 11.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 11.9.1 Amalgam Tattoo 11.9.2 Oral Melanoacanthoma 11.9.3 Oral Melanocytic Naevus 11.10 What Is the Most Likely Diagnosis? 11.11 How Would You Investigate This Patent? 11.12 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 11.13 Biopsy Report Confirms the Previous Clinical Diagnosis of Oral Melanotic Macule. What Are the Histopathological Features That Will Help in the Diagnosis? 11.14 How Would You Manage This Patent? 11.15 Oral Melanotic Macule (Focal Melanosis) Further Reading 12: Blue-Purple Lump on the Lip: Haemangioma/Vascular Anomaly 12.1 Main Complaint 12.2 History of Complaint 12.3 From the findings of the history, what is your Differential Diagnosis? 12.4 How do you justify your Differential Diagnosis reached from the findings of the history? 12.5 Clinical Examination Findings 12.6 What other features would you look for in formulating a Clinical Diagnosis? 12.7 What is your Clinical Diagnosis? 12.8 How would you exclude other conditions and justify the Iinclusion of the disease entity that you have mentioned as the Clinical Diagnosis? 12.9 What is the most likely working diagnosis? 12.10 How would you investigate this patient? 12.11 If a biopsy was to be performed, what are the important considerations? 12.12 The biopsy report confirms the previous Clinical Diagnosis of Vascular Malformation. What are the Histopathological Features that help in confirming the diagnosis? 12.13 How could you manage this patient? 12.14 Vascular Anomalies/Haemangioma 12.15 Management of Vascular Lesions 12.15.1 Haemangiomas 12.15.2 Vascular Malformations Further Reading 13: Reddish Growths on the Hard Palate: Kaposi Sarcoma 13.1 Main Complaint 13.2 History of Complaint 13.3 Additional Complaints 13.4 With the Findings of the History, What Is Your Differential Diagnosis? 13.5 How Would You Justify Your Differential Diagnosis After History Taking? 13.6 Findings of Clinical Examination 13.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 13.8 What Is Your Clinical Diagnosis? 13.9 How Would You Exclude Other Conditions and Justify Your Clinical Diagnosis? 13.10 What Is the Most Likely Diagnosis? 13.11 How Would You Investigate This Patient? 13.12 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 13.13 Biopsy Report Confirms the Previous Clinical Diagnosis of Kaposi Sarcoma. What Are the Histopathological Features That Would Help in the Diagnosis? 13.14 How Would You Manage This Patient? 13.15 Kaposi Sarcoma Further Reading V: Fibro-Cemento Osseous Lesions 14: Slow Growing Hard Lump over the Cheek: Fibrous Dysplasia 14.1 Main Complaint 14.2 History of Complaint 14.3 Additional Complaints 14.4 With the Findings from the History, What Is Your Differential Diagnosis? 14.5 How Do You Justify Your Differential Diagnosis After History Taking? 14.6 Findings of Clinical Examination 14.7 What Other Relevant Features Would You Look for with the Findings You Have so Far? 14.8 What Is Your Clinical Differential Diagnosis? 14.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 14.10 What Radiologic Investigations Would You Need to Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 14.11 What Is the Most Likely Diagnosis? 14.12 How Would You Further Investigate This Patent? 14.13 How Would You Perform an Incisional Biopsy for This Patient? What Are the Important Considerations? 14.14 Biopsy Report Confirms the Previous Clinical Diagnosis of Craniofacial Fibrous Dysplasia. What Are the Histopathological Features That Will Help in the Diagnosis? 14.15 How Would You Manage This Patent? 14.16 Fibrous Dysplasia (FD) Further Reading 15: Fast Growing Bony Hard Lump: Cemento-ossifying Fibroma 15.1 Main Complaint 15.2 History of Complaint 15.3 Additional Complaints 15.4 With the Findings from the History, What Is Your Differential Diagnosis? 15.5 How Do You Justify Your Differential Diagnosis After History Taking? 15.6 Findings of Clinical Examination 15.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 15.8 What Is Your Clinical Differential Diagnosis? 15.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 15.10 What Radiologic Investigations Would You Need to Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 15.11 What Is the Most Likely Working Diagnosis? 15.12 How Would You Further Investigate This Patent? 15.13 How Would You Arrive at a Definitive Diagnosis? 15.14 How Would You Perform an Incisional Biopsy for This Patient? What Are the Important Considerations? 15.15 Biopsy Report Confirms the Previous Clinical and Radiological Diagnosis of Cemento-ossifying Fibroma. What Are the Histopathological Features That Help in the Diagnosis? 15.16 What Is the Final Diagnosis? 15.17 How Would You Manage This Patent? 15.18 Cemento-ossifying Fibroma (COF) Further Reading 16: Accidental Finding on the Radiograph: Periapical Cemento-osseous Dysplasia 16.1 Main Complaint 16.2 History of Complaint 16.3 Additional Complaints 16.4 With the Findings from the History, What Is Your Differential Diagnosis? 16.5 How Do You Justify Your Differential Diagnosis After History Taking? 16.6 Findings of Clinical Examination 16.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 16.8 What Is Your Clinical Differential Diagnosis? 16.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 16.10 How Would You Investigate This Patient? 16.11 What Is the Most Likely Diagnosis? 16.12 What Further Investigations Would You Recommend for This Patient? 16.13 Biopsy Report Confirms the Previous Clinical Diagnosis of Periapical Cemento-osseous Dysplasia. What Are the Histopathological Features That Help in the Diagnosis? 16.14 What Is the Final Diagnosis? 16.15 How Would You Manage This Patient? 16.16 Periapical Cemento-osseous Dysplasia (PCOD) Further Reading 17: Multiple Radiopaque Masses in the Lower Jaw: Florid Cemento-Osseous Dysplasia 17.1 Main Complaint 17.2 History of Complaint 17.3 Additional Complaints 17.4 With the Findings From the History, What Is Your Differential Diagnosis? 17.5 How Do You Justify Your Differential Diagnosis After History Taking? 17.6 Findings of Examination 17.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 17.8 What Is Your Clinical Differential Diagnosis? 17.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 17.10 What Is the Most Likely Diagnosis? 17.11 How Would You Investigate This Patient? 17.12 Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 17.13 What Are the Histopathological Features That Help in the Diagnosis? 17.14 What Is the Final Diagnosis? 17.15 How Would You Manage This Patient? 17.16 Florid Cemento-osseous Dysplasia (FCOD) Further Reading VI: Reactive Lesions and Benign Tumours of the Oral Mucosa 18: Painless Nodule on the Cheek: Fibroepithelial Polyp 18.1 Main Complaint 18.2 History of Complaint 18.3 Additional Complaints 18.4 What Is Your Differential Diagnosis After History Taking? 18.5 How Do You Justify Your Differential Diagnosis After History Taking? 18.5.1 Fibroepithelial Polyp (FEP) 18.5.2 Squamous Cell Papilloma 18.5.3 Mucocele 18.5.4 Benign Tumours Including Salivary Gland Tumour 18.6 Findings of Clinical Examination 18.7 What Is Your Clinical Differential Diagnoses? 18.8 How Do You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 18.8.1 Fibroepithelial Polyp 18.8.2 Squamous Cell Papilloma 18.8.3 Enlarged Papilla of the Parotid Duct 18.8.4 Mucocele 18.8.5 Benign Tumours Including Salivary Gland Tumours 18.9 What Is the Most Likely Diagnosis? 18.10 How Would You Investigate This Patient? 18.11 How do You Confirm the Diagnosis for This Lesion? 18.12 What Specific Findings Help You to Arrive at the Diagnosis (History, Clinical Findings and Investigations)? 18.13 What Is Your Definitive Diagnosis? 18.14 What Is the Treatment? 18.15 Fibroepithelial Polyp Further Reading 19: Red Lump on the Gum: Pyogenic Granuloma 19.1 Main Complaint 19.2 History of Complaint 19.3 How Do You Justify Your Differential Diagnoses After History Taking? 19.4 Findings of Clinical Examination 19.5 What Is Your Most Likely Clinical Diagnosis? 19.6 How Would You Investigate This Patient? 19.7 What Are the Specific Findings to Help You Arrive at the Diagnosis (History, Clinical, and Investigations)? 19.8 What Is the Definitive Diagnosis? 19.9 Why Are the Differential Diagnoses Stated Earlier Excluded? 19.9.1 Peripheral Giant Cell Granuloma 19.9.2 Fibrous Epulis 19.9.3 Hemangioma 19.9.4 Neoplasm 19.10 What Is the Treatment for This Patient? 19.11 Pyogenic Granuloma Further Reading 20: Lump on the Tongue: Schwannoma 20.1 Main Complaint 20.2 History of Complaint 20.3 Additional Complaints 20.4 With the Findings From the History, What Are Your Differential Diagnoses? 20.5 How Would You Justify Your Differential Diagnoses After History Taking? 20.6 Findings of Clinical Examination 20.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 20.8 What Is Your Clinical Differential Diagnosis? 20.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnoses to Arrive at a Working Diagnosis? 20.9.1 Pyogenic Granuloma 20.9.2 Lipoma 20.9.3 Haemangioma/Mucocele 20.10 What Is the Most Likely Diagnosis? 20.11 How Would You Investigate This Patient in Order to Arrive at the Final Diagnosis? 20.12 What Does the Histopathological Examination Reveal? 20.13 Schwannoma Further Reading VII: Oral Potentially Malignant Disorders and Oral Cancer 21: Burning Sensation to Spicy Food: Oral Submucous Fibrosis 21.1 Main Complaint 21.2 History of Complaint 21.3 Additional Complaints 21.4 With the Findings in the History, What Is Your Differential Diagnosis? 21.5 How Do You Justify Your Differential Diagnosis After History Taking? 21.6 Findings of Clinical Examination 21.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 21.8 What is Your Clinical Diagnosis? 21.9 How Would You Exclude Other Conditions and Justify Your Clinical Diagnosis? 21.9.1 Candidosis 21.9.2 Scleroderma 21.9.3 Oral Lichen Planus and Anaemia 21.9.4 OSF 21.10 What is the Most Likely Diagnosis? 21.11 How Would You Investigate This Patient? 21.12 How Would You Do an Incisional Biopsy for This Patient? What are the Important Considerations? 21.13 What are the Histopathological Features That Help in Arriving at the Diagnosis? 21.14 What is the Significance of the Presence of Epithelial Dysplasia in OSF? 21.15 How Would You Manage This Patient? 21.16 Oral Submucous Fibrosis (OSF) Further Reading 22: White Patch on the Buccal Mucosa: Leukoplakia 22.1 Main Complaint 22.2 History of Complaint 22.3 Past Medical History 22.4 Past Dental History 22.5 Social History 22.6 Findings of Extra-Oral Examination 22.7 Findings of Intraoral Examination 22.8 What Are Your Differential Diagnoses for This White Patch on the Left Buccal Mucosa After History Taking and Clinical Examination? 22.9 What Is the Most Likely Clinical Diagnosis for This White Patch on the Buccal Mucosa? 22.10 What Investigations Need to Be Carried Out for This Patient? 22.11 What Are the Histopathological Features of the Submitted Specimen? 22.12 What Is the Definitive Diagnosis for This Lesion? 22.13 What Specific Findings Helped You to Arrive at the Diagnosis of Oral Leukoplakia with Mild Epithelial Dysplasia? 22.14 How Do You Manage This Patient? 22.15 What Is the Prognosis for Homogenous Oral Leukoplakia with Mild Epithelial Dysplasia? 22.16 Oral Leukoplakia 22.16.1 Clinical Features 22.16.2 Investigations 22.16.3 Tissue Biopsy 22.16.4 Histopathological Features 22.16.5 Treatment 22.16.6 Prognosis Further Reading 23: A Red Patch on the Cheek: Erythroplakia 23.1 Main Complaint 23.2 History of Complaint 23.3 Additional Complaints 23.4 With the Findings From the History, What Is Your Differential Diagnosis? 23.5 How Do You Justify Your Differential Diagnosis After History Taking? 23.6 Findings of Clinical Examination 23.7 What Is Your Clinical Differential Diagnosis? 23.8 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 23.8.1 Oral Cancer 23.8.2 Erythroplakia 23.8.3 Traumatic Lesion 23.9 What Is the Most Likely Clinical Diagnosis? 23.10 How Would You Investigate This Patent? 23.11 What Are the Histopathological Features That Help in the Diagnosis? 23.12 How Would You Manage This Patent? 23.13 Erythroplakia Further Reading 24 : Painful Mouth: Oral Lichen Planus 24.1 Main Complaint 24.2 History of Complaint 24.3 With the Findings From the History, What Is Your Differential Diagnosis? 24.4 How Do You Justify Your Differential Diagnosis After History Taking? 24.5 Findings of Clinical Examination 24.6 What Is Your Most Likely Clinical Diagnosis? 24.7 How Would You Exclude Other Conditions and Justify Your Clinical Diagnosis to Arrive at a Working Diagnosis? 24.7.1 Oral Lichenoid Reaction 24.7.2 Lupus Erythematosus 24.7.3 Mucous Membrane Pemphigoid (MMP) 24.7.4 Candidosis 24.8 How Would You Investigate This Patient? 24.9 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 24.10 The Specimen Was Sent for Histopathological Examination. What Are the Histological Findings? 24.11 What Is Your Definitive Diagnosis Based on the Clinical and Histopathological Findings? 24.12 How Would You Manage This Patient? 24.13 Oral Lichen Planus Further Reading 25: Non-healing Ulcer in the Right Lateral Surface of the Tongue: Oral Cancer 25.1 Main Complaint 25.2 History of Complaint 25.3 Findings of Extra-Oral Examination 25.4 Findings of Intraoral Examination 25.5 What Is Your Clinical Differential Diagnoses? 25.6 What Is Your Justification for the Differential Diagnoses? 25.7 What Is Your Working Diagnosis? 25.8 How Would You Investigate This Patient? 25.9 What Are the Histopathological Features of the Submitted Specimen? 25.10 What Is Your Definitive Diagnosis 25.11 What Specific Findings Help You to Arrive at the Diagnosis of Oral Squamous Cell Carcinoma? 25.12 How Would You Manage This Patient? 25.12.1 Imaging 25.13 What Is the Definitive Treatment Given for This Patient? 25.14 How Would You Follow-Up This Patient and What Is the Prognosis? 25.15 Oral Squamous Cell Carcinoma 25.15.1 Metastasis to Neck Nodes 25.16 Investigations 25.16.1 Imaging 25.17 Histopathological Examination 25.18 Histopathological Features 25.18.1 Histopathological Grading 25.18.2 Treatment 25.18.3 Dental Practitioners’ Role 25.18.4 Prognosis Further Reading VIII: Tumours of Odontogenic Origin 26: Large Swelling of the Back of the Lower Jaw: Ameloblastoma 26.1 Main Complaint 26.2 History of Complaint 26.3 Past Dental, Medical and Social History 26.4 Findings of Clinical Examination 26.5 What is your Differential Diagnosis with the findings from the History and Clinical Examination? Give a justification for including different entities. 26.6 What is the most likely Clinical Diagnosis? 26.7 What are the necessary investigations that should be performed in a logical sequence? 26.7.1 Pulp Sensibility Test 26.7.2 Dental Pantomograph (DPT) 26.7.3 Aspiration Biopsy 26.7.4 Incision Biopsy 26.8 What were the Histopathological findings? 26.9 Three-dimensional (3D) imaging 26.10 What is the definitive diagnosis? 26.11 What specific findings help you to arrive at the diagnosis? 26.12 What is the rationale for treatment? 26.13 Follow-up and Prognosis 26.14 Ameloblastoma 26.14.1 Definition and Epidemiology 26.14.2 Clinical Presentation 26.14.3 Radiological Appearance 26.14.4 Histopathology 26.14.5 Conventional Ameloblastoma 26.14.6 Unicystic Ameloblastoma 26.14.7 Peripheral Ameloblastoma 26.14.8 Metastasizing Ameloblastoma 26.15 Diagnostic Challenges (Clinical/Radiological/Histopathological) 26.16 Treatment Strategies 26.17 New Advances Further Reading 27 : Swelling in the Left Maxilla: Adenomatoid Odontogenic Tumour (AOT) 27.1 Main Complaint 27.2 History of Complaint 27.3 Additional Complaints 27.4 Past Medical/Dental and Social History 27.5 With the Findings From the History, What Is Your Differential Diagnosis? 27.6 How Do You Justify Your Differential Diagnosis After History Taking? 27.7 Findings of Clinical Examination 27.8 What Other Relevant Features Are Evident? 27.9 What Is Your Clinical Differential Diagnosis? 27.10 What Is the Justification for Your Clinical Differential Diagnosis? 27.10.1 Adenomatoid Odontogenic Tumour (AOT) 27.10.2 Dentigerous Cyst 27.10.3 Odontogenic Keratocyst (OKC) 27.10.4 Ameloblastoma 27.10.5 Odontogenic Myxoma 27.11 How Would You Investigate the Patient? 27.12 What Would Be the Best Imaging Modality to Investigate This Lesion? 27.13 What Are the Findings of Radiographic Investigations? 27.13.1 CT Scan Findings 27.14 What Is the Most Likely Working Diagnosis with the History, Clinical and Radiological Findings? 27.15 What Are the Characteristic Histopathological Features of an Adenomatoid Odontogenic Tumour? 27.16 How Would You Treat This Patient? 27.17 What Is the Prognosis for AOT? 27.18 Adenomatoid Odontogenic Tumour (AOT) 27.18.1 Investigations 27.18.2 Treatment and Prognosis Further Reading 28: A Rapidly Growing Swelling in the Posterior Mandible: Clear Cell Odontogenic Carcinoma 28.1 Main Complaint 28.2 History of Complaint 28.3 Additional Complaints 28.4 With the Findings From the History, What Is Your Differential Diagnosis? 28.5 How Do You Justify Your Differential Diagnosis After History Taking? 28.6 Findings of Clinical Examination 28.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 28.8 What Is Your Clinical Differential Diagnosis? 28.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 28.10 What Is the Most Likely Diagnosis and Why? 28.11 How Would You Investigate This Patient? 28.12 How Would You Do An Incisional Biopsy for This Patient? What Are the Important Considerations? 28.13 What Specific Histopathological Features Are Helpful Leading to the Definitive Diagnosis? 28.14 What Is the Most Likely Diagnosis? 28.15 What Other Findings and Investigations Would Help You to Confirm the Diagnosis? 28.16 What Other Investigations You Would Perform in Order to Confirm the Diagnosis? Explain the Specific Reasons to Carry Out Them? 28.17 What Is the Treatment for CCOC? 28.18 Clear Cell Odontogenic Carcinoma Further Reading IX: Developmental Alterations of the Oral Mucosa 29: Bilateral White Patches on the Cheek: White Sponge Naevus 29.1 Main Complaint 29.2 History of Complaint 29.3 Additional Complaints 29.4 With the Findings From the History, What Is Your Differential Diagnoses? 29.5 How Do You Justify Your Differential Diagnosis After History Taking? 29.6 Findings of Clinical Examination 29.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 29.8 What Is Your Clinical Diagnosis? 29.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 29.9.1 Leukoedema 29.9.2 Oral Lichen Planus 29.9.3 Pseudomembranous Candidosis 29.10 What Is the Most Likely Diagnosis? 29.11 How Would You Investigate This Patent? 29.12 How Would You Do An Incisional Biopsy for This Patient? What Are the Important Considerations? 29.13 What Are the Histopathological Features That Help in the Diagnosis? 29.14 How Would You Manage This Patent? 29.15 White Sponge Naevus (WSN) Further Reading 30 : Bilateral Whitish Patches on the Inner Cheek: Leukoedema 30.1 Main Complaint 30.2 History of Complaint 30.3 Past Medical History 30.4 Past Dental History 30.5 Social History 30.6 What Is Your Differential Diagnosis with the Findings From the History? 30.7 How Do You Justify Your Differential Diagnosis? 30.8 What Are the Findings of Clinical Examination? 30.8.1 Extra-oral 30.8.2 Intra-oral 30.9 What Is Your Clinical Diagnosis? 30.10 How Do You Investigate the Patient to Confirm Your Diagnosis? 30.11 Do You Need to Do a Biopsy to Confirm the Diagnosis of Leukoedema? 30.12 What Histological Features Would You Expect to See If a Biopsy Is Performed? 30.13 What Is the Definitive Diagnosis? 30.14 How Would You Justify Your Definitive Diagnosis? 30.15 How Would You Manage This Patient? 30.16 Leukoedema Further Reading 31: Irregular Red Patches on the Dorsum of the Tongue: Benign Migratory Glossitis 31.1 Main Complaint 31.2 History of Complaint 31.3 Additional Complaints 31.4 With the Findings From the History, What Is Your Differential Diagnosis? 31.5 How Do You Justify Your Differential Diagnosis After History Taking? 31.6 Findings of Clinical Examination 31.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 31.8 What Is Your Clinical Differential Diagnosis? 31.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 31.9.1 BMG 31.9.2 Anaemia 31.10 Median Rhomboid Glossitis (MRG) 31.11 Erosive Oral Lichen Planus (EOLP) 31.12 What Is the Most Likely Diagnosis? 31.13 How Would You Investigate This Patent? 31.14 What Findings Would You Expect From the Above Investigations? 31.15 How Can We Confirm the Diagnosis of BMG? 31.16 What Are the Histopathological Features of BMG? 31.17 How Would You Manage This Patent? 31.18 What Is the Follow-Up Plan and Prognosis? 31.19 Benign Migratory Glossitis (BMG) Further Reading X: Oral Mucosal Ulcerations 32: Ulceration Related to New Dentures: Traumatic Ulcer 32.1 Chief Complaint 32.2 History of Complaint 32.3 With the Findings From the History, What Is Your Differential Diagnosis? 32.4 How Do You Justify Your Differential Diagnosis After History Taking? 32.5 Findings of Clinical Examination 32.6 What Is the Most Likely Clinical Differential Diagnosis? 32.7 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Clinical Differential Diagnosis? 32.8 What is the Most Likely Diagnosis? 32.9 How Would You Investigate This Patient? 32.10 Should a Biopsy Be Done Immediately? 32.11 If a Traumatic Ulcer Does Not Heal, A Biopsy Should Be Performed. How Would It Appear Under the Microscope? 32.12 What Is the Final Diagnosis? 32.13 How Would You Manage This Patient? 32.14 Traumatic Oral Ulcer Further Reading 33: A Painful Non-healing Ulcer on the Tongue: Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE) 33.1 Complaint 33.2 History of Complaint 33.3 Past Dental and Medical and Social History 33.4 With the Findings From the History, What Is Your Differential Diagnosis? 33.5 How Do You Justify Your Differential Diagnosis After History Taking? 33.5.1 Major Aphthous Ulcer 33.5.2 Traumatic Ulcer/Traumatic Ulcerative Granuloma with Stromal Eosinophilia 33.5.3 Primary Syphilis (Syphilitic Chancre) 33.5.4 Necrotizing Sialometaplasia 33.5.5 Oral Squamous Cell Carcinoma (OSCC) 33.6 Findings of Clinical Examination 33.6.1 Extra-oral Examination 33.6.2 Intra-oral Examination 33.7 What Is Your Clinical Differential Diagnosis? 33.8 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 33.9 How Would You Investigate This Patient? 33.10 How Would You Do An Incisional Biopsy for This Patient? What Are the Important Considerations? 33.11 What Are the Histopathological Features? 33.12 What Specific Findings Help You to Arrive at the Diagnosis (History, Clinical and Investigations)? 33.13 What Is Your Definitive Diagnosis? 33.14 What Is the Treatment and Prognosis? 33.15 Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE) Further Reading 34 : Crusting and Ulceration of Lips: Erythema Multiforme 34.1 Main Complaint 34.2 History of Complaint 34.3 Additional Complaints 34.4 With the Findings From the History, What Is Your Differential Diagnosis? 34.5 How Do You Justify Your Differential Diagnosis After History Taking? 34.5.1 Erythema multiforme (EM) 34.5.2 Mucocutaneous Autoimmune Blistering Disorder 34.5.3 Oral Lichenoid Reaction (OLR) 34.5.4 Herpes Simplex Virus (HSV) Infection 34.6 Findings of Clinical Examination 34.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 34.8 What Is Your Clinical Differential Diagnosis? 34.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 34.10 What Is the Most Likely Diagnosis and Why? 34.11 How Would You Investigate This Patient? 34.12 How Would You Do An Incisional Biopsy for This Patient? What Are the Important Considerations? 34.13 What Histopathological Features Are Helpful to Arrive at the Definitive Diagnosis? 34.14 What Is the Definitive Diagnosis? 34.15 What Is the Treatment Protocol? 34.16 Erythema Multiforme (EM) Further Reading 35: Painful Recurrent Ulcers in the Mouth: Aphthous Ulcers 35.1 Main Complaint 35.2 History of Complaint 35.3 How Do You Justify Your Differential Diagnosis After History Taking? 35.4 What Are the Clinical Examination Findings? 35.5 What Are the Clinical Differential Diagnoses? 35.6 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnoses to Arrive at a Working Diagnosis? 35.7 What Is the Most Likely Diagnosis? 35.7.1 Recurrent Aphthous Major (RAU) 35.8 How Would You Investigate This Patient? 35.9 Recurrent Aphthous Ulcers Further Reading XI: Infections of the Oral Cavity 36: Multiple White Lesions of Recent Onset: Candidosis 36.1 Main Complaint 36.2 History of Complaint 36.3 Additional Complaints 36.4 With the Findings From the History, What is Your Differential Diagnosis? 36.5 How Do You Justify Your Differential Diagnosis After History Taking? 36.6 Findings of Examination 36.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 36.8 What Is Your Clinical Diagnosis? 36.9 How Would You Arrive At This Working Diagnosis? 36.10 How Would You Confirm Your Clinical Diagnosis? 36.11 How Would You Manage This Patent? 36.12 Oral Candidosis 36.13 Clinical Presentation of Oral Candidosis 36.14 Pseudomembranous Candidosis/Oral Thrush 36.15 Acute Erythematous Candidosis 36.16 Chronic Hyperplastic Candidosis 36.17 Candida-Associated Denture Stomatitis/Chronic Atrophic Candidosis/Chronic Erythematous Candidosis 36.18 Angular Cheilitis 36.19 Median Rhomboid Glossitis (MRG) 36.20 Management of Oral Candidosis Further Reading 37: Slow Growing Lump on the Labial Mucosa: HPV Infection (Squamous Cell Papilloma/ Condyloma/ Viral Wart) 37.1 Main Complaint 37.2 History of Complaint 37.3 Additional Complaints 37.4 With the Findings From the History, What is Your Differential Diagnosis? 37.5 How Do You Justify Your Differential Diagnosis After History Taking? 37.6 Findings of Examination 37.7 What are the Other Relevant Features That You Will Look For? 37.8 What is Your Clinical Differential Diagnosis? 37.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 37.9.1 Squamous Cell Papilloma 37.9.2 Condyloma Acuminatum 37.9.3 Verruca Vulgaris (Viral Wart) 37.10 What is the Most Likely Diagnosis? 37.11 How Would You Investigate This Patient? 37.12 What are the Risk Factors for Oral HPV? 37.13 How Would You Manage This Patient? 37.14 What are the Histopathological Features of Squamous Cell Papilloma? 37.15 What are the Important Histopathological Differential Diagnosis of Squamous Cell Papilloma? 37.16 Oral Manifestations of HPV Infections 37.16.1 Oral Squamous Cell Papilloma 37.16.2 Condyloma Acuminatum 37.16.3 Verruca Vulgaris/Viral Wart 37.16.4 Multifocal Epithelial Hyperplasia (Heck’s Disease) 37.16.5 Management of Common Oral HPV Lesions Further Reading 38: Pustules on One Side of the Face: Herpes Zoster 38.1 Main Complaint 38.2 History of Complaint 38.3 Additional Complaints 38.4 With the Findings from the History, What is Your Differential Diagnosis? 38.5 How Do You Justify Your Differential Diagnosis After History Taking? 38.6 Findings on Examination 38.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 38.8 What is Your Clinical Diagnosis? 38.9 How Would You Justify Your Clinical Diagnosis? 38.10 How Would You Manage This Patient? 38.11 What are the Complications of This Condition? 38.12 Herpes Zoster (Shingles) and Post-herpetic Neuralgia 38.12.1 Prodrome 38.12.2 Rash 38.12.2.1 Resolution Further Reading 39: Non-healing Ulcer on the Palate in a Long-Term Diabetic Patient: Deep Fungal Infection 39.1 Main Complaint 39.2 History of Complaint 39.3 Additional Complaints 39.4 With the Findings from the History, What Is Your Differential Diagnosis? 39.5 How Do You Justify Your Differential Diagnosis After History Taking? 39.6 Findings of Clinical Examination 39.7 What Is Your Clinical Differential Diagnosis? 39.8 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 39.9 How Would You Investigate This Patient? 39.10 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 39.11 Biopsy Report Confirms the Previous Clinical Diagnosis of Mucormycosis. What Are the Histopathological Features That Help in the Diagnosis? 39.12 What Is the Final Diagnosis? 39.13 How Would You Manage This Patient? 39.14 Mucormycosis Further Reading 40: Deep-Seated Lump in the Buccal Mucosa: Dirofilariasis 40.1 Main Complaint 40.2 History of Complaint 40.3 Additional Complaints 40.4 With the Findings from the History, What is Your Differential Diagnosis? 40.5 How Do You Justify Your Differential Diagnosis After History Taking? 40.6 Findings of Clinical Examination 40.7 What is Your Clinical Differential Diagnosis? 40.8 How Would You Justify the Inclusion of the Diseases Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 40.9 How Would You Investigate This Patient? 40.10 What is the Next Step in the Management of this Patient? 40.11 What are the Histopathological Features Helpful to Arrive at the Definitive Diagnosis? 40.12 What is the Most Likely Diagnosis? 40.13 What are the Specific Histopathological Features of Dirofilaria? 40.14 How Would You Manage This Patient? 40.15 Oral Dirofilariasis Further Reading 41: Inabilty to Wear Dentures: Denture-Induced Stomatitis 41.1 Main Complaint 41.2 History of Complaint 41.3 Additional Complaints 41.4 With the Findings from the History, What Is Your Differential Diagnosis? 41.5 Findings on Clinical Examination 41.6 How Would You Identify Poor Denture Hygiene If Deposits Are Not Visible Clinically? 41.7 With the History and Clinical Findings, What Is Your Differential Diagnosis? 41.8 How Do You Justify Your Differential Diagnosis? 41.9 What Is the Most Likely Clinical Diagnosis and Your Justification? 41.10 How Would You Investigate This Patient? 41.11 How Would You Manage This Patient? 41.12 Denture-Induced Stomatitis 41.12.1 Prosthetic Factors 41.12.2 Infectious Factors Further Reading 42: Fever with Ulcers in the Mouth: Herpes Simplex Infection 42.1 Main Complaint 42.2 History of Complaint 42.3 Additional Complaints 42.4 With the Findings from the History, What is Your Differential Diagnosis? 42.5 How Do You Justify Your Differential Diagnosis After History Taking? 42.6 Findings of Examination 42.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 42.8 What is Your Working Diagnosis After History Taking and Clinical Examination? 42.9 How Would You Investigate This Patient? 42.10 What is the Significance of Immune Status of the Patient? 42.11 How Would You Manage This Patient? 42.12 What is the Possible Complication of this Condition? 42.13 Primary Herpetic Gingivostomatitis Further Reading 43: Persistent Ulcer on the Tongue with Cough: Tuberculosis 43.1 Main Complaint 43.2 History of Complaint 43.3 Additional Complaints 43.4 With the Findings from the History, What Is Your Differential Diagnosis? 43.5 How Do You Justify Your Differential Diagnosis after History Taking? 43.6 Findings of Clinical Examination 43.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 43.8 What Is Your Clinical Differential Diagnosis? 43.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 43.9.1 Tuberculous Ulcer 43.9.2 Deep Fungal Infection 43.9.3 Oral Cancer 43.10 How Would You Investigate This Patient? 43.11 His Biopsy Report Confirms the Clinical Diagnosis of TB. What Are the Histopathological Features that Help in the Diagnosis? 43.12 What Are the Findings Expected to be Seen in Other Investigations? 43.13 How Would You Manage This Patient? 43.14 Tuberculosis Further Reading 44: Painful Swelling in the Face and Neck: Odontogenic Infection 44.1 Main Complaint 44.2 History of Complaint 44.3 Past Dental, Medical, and Social History 44.4 Clinical Examination 44.5 What Is Your Differential Diagnosis with the Findings from the History and Clinical Examination? Justify the Inclusion of Different Entities 44.6 What Is the Most Likely Clinical Diagnosis? 44.7 How Would You Manage This Patient? 44.8 What are the Necessary Investigations that Should Be Performed Out in a Logical Sequence? 44.8.1 Laboratory Findings (On Admission to Hospital): 44.8.2 Pulp Sensibility Test 44.8.3 Dental Pantomography (DPT) 44.8.4 Aspiration 44.8.5 Computerised Tomography Scanning (CT) 44.9 What Is the Definitive Diagnosis? 44.10 What Specific Findings Help You to Arrive at the Definitive Diagnosis? 44.11 How Would You Treat This Patient? 44.12 What Is the Rationale for Treatment Provided? 44.13 Follow-up and Prognosis 44.14 Odontogenic Infections 44.14.1 Definition and Epidemiology 44.14.2 Clinical Presentation 44.14.3 Principles of Management 44.14.4 Assess the Severity and Decide the Setting of Care 44.14.5 Determine the Level of Integrity of Host Defences 44.14.6 Determine and Eliminate the Source of Infection 44.14.7 Establish and Maintain Drainage 44.14.8 Administer Appropriate Antibiotics as Necessary 44.14.9 Support and Monitor General Health and Regularly Review Clinical Progress 44.14.10 Follow-up Focused on Prevention 44.14.11 Complications Further Reading 45: Pain in the Lower Jaw with Numbness of the Lip: Osteomyelitis of the Mandible 45.1 Main Complaint 45.2 History of Complaint 45.3 Past Medical History 45.4 Past Dental History 45.5 Social History and Family History 45.6 With the Information From the History, What Is Your Differential Diagnosis? 45.7 How Would You Justify your Differential Diagnosis after Taking the History? 45.8 Findings of Clinical Examination 45.9 What Is Your Clinical Differential Diagnosis? 45.10 Explain the Justification for Your Clinical Differential Diagnosis 45.11 What Is the Working Diagnosis? 45.12 How Would You Investigate This Patient? 45.13 What Is the Most Likely Diagnosis? 45.14 How Would You Manage This Patient? 45.15 What Are the Histopathological Findings of the Surgically Removed Lesional Tissue? 45.16 Osteomyelitis 45.16.1 The Zurich Classification of Osteomyelitis of the Jaws Further Reading 46: Painless and Exposed Bone in the Maxilla: Medication-Related Osteonecrosis of the Jaw (MRONJ) 46.1 Main Complaint 46.2 History of Complaint 46.3 Additional Complaints 46.4 With the Findings From the History, What Is Your Differential Diagnosis? 46.5 How Do You Justify Your Differential Diagnosis After History Taking? 46.6 Findings of Clinical Examination 46.7 What Other Relevant Features Do You Look for with the Findings You Have So Far? 46.8 What Is Your Clinical Differential Diagnosis? 46.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 46.9.1 Medication-Related Osteonecrosis of the Jaws (MRONJ) 46.9.2 Osteoradionecrosis (ORN) 46.9.3 Osteomyelitis 46.9.4 Metastatic Lesion 46.9.5 What Is the Most Likely Diagnosis? 46.9.6 How Would You Investigate This Patient? 46.9.7 A DPT Was Taken for This Patient. What Features Do You See in This DPT? 46.9.8 Is Biopsy Always Necessary in All Cases? 46.9.9 What Do You Expect to See If Biopsy Is Performed? 46.9.10 How Would You Manage This Patient? 46.10 Medication-Related Osteonecrosis of the Jaws (MRONJ) Suggested Readings XII: Oral Manifestations of Autoimmune Disorders 47: Blisters and Ulcers on the Soft Palate: Pemphigus 47.1 Main Complaint 47.2 History of Complaint 47.3 Additional Complaints 47.4 With the Findings from the History, What Is Your Differential Diagnosis? 47.5 How Do You Justify Your Differential Diagnosis after History Taking? 47.6 Findings of Clinical Examination 47.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 47.8 What Is Your Clinical Differential Diagnosis? 47.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 47.10 What Is the Most Likely Diagnosis and Why? 47.11 How Would You Investigate This Patient? 47.12 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 47.13 What Specific Histopathological Features Are Helpful to Arrive at the Definitive Diagnosis? 47.14 What Is the Definitive Diagnosis? 47.15 What Is the Treatment Protocol? 47.16 Pemphigus Vulgaris Suggested Readings 48: A Patient Presenting with Desquamative Gingivitis: Mucous Membrane Pemphigoid 48.1 Main Complaint 48.2 History of Complaint 48.3 Additional Complaints 48.4 With the Findings from the History, What is Your Differential Diagnosis? 48.5 How Do You Justify Your Differential Diagnosis After History Taking? 48.6 Findings of Clinical Examination 48.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 48.8 What is Your Clinical Differential Diagnosis? 48.9 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis? 48.10 What is the Most Likely Diagnosis and Why? 48.11 How Would You Investigate This Patient? 48.12 How Would You Do an Incisional Biopsy for This Patient? What are the Important Considerations? 48.13 The Haematoxylin & Eosin Stained Sections from the Biopsy Showed a Subepithelial Blister. What Specific Histopathological Features and Immunofluorescence Findings are Helpful to Arrive at the Definitive Diagnosis? 48.14 What is the Definitive Diagnosis? 48.15 How Do You Manage This Patient? 48.16 Mucous Membrane Pemphigoid Suggested Readings XIII: Oral Manifestations of Hematological Disorders 49: Multiple Reddish Swellings on the Gum: Leukemia 49.1 Main Complaint 49.2 History of Complaint 49.3 Based on the Findings From the Patient's History, What Is Your Differential Diagnosis? 49.4 How Do You Justify Your Differential Diagnosis Based on the History? 49.5 What Are the Findings of the Clinical Examination? 49.6 What Is Your Clinical Differential Diagnosis? 49.7 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 49.8 What is the Most Likely Diagnosis? 49.9 What Special Investigations Are Needed to Confirm Your Diagnosis? 49.10 How Would You Do an Incisional Biopsy for This Patient? What Are the Important Considerations? 49.11 What Other Relevant Features Would You Look for with Your Findings So Far? 49.12 What Is the Definitive Diagnosis? 49.13 How Would You Manage This Patient? 49.14 Leukemia 49.14.1 Acute Lymphocytic Leukemia (ALL) 49.14.2 Chronic Lymphocytic Leukaemia (CLL) 49.14.3 Acute Myeloid Leukemia (AML) 49.14.4 Chronic Myeloid Leukemia (CML) 49.14.5 Oral Manifestations of Leukemia 49.15 Dentist's Role in Management Further Reading 50: Generalized Weakness and Recurrent Ulcers on the Tongue: Anemia 50.1 Main Complaint 50.2 History of Complaint 50.3 Past Medical History 50.4 Past Dental History 50.5 Social History 50.6 What Is Your Differential Diagnosis with the Findings from the History? 50.7 How Do You Justify Your Differential Diagnosis? 50.8 What Are the Findings of Clinical Examination? 50.8.1 Extra Oral 50.8.2 Intraoral 50.9 What Is Your Clinical Diagnosis? 50.10 How Would You Exclude Other Conditions Leading to Oral Ulceration from Your Differential Diagnosis and Justify Your Clinical Diagnosis? 50.11 How Do You Investigate the Patient to Confirm Your Diagnosis? 50.12 What Is Your Definitive Diagnosis? 50.13 What Are the Specific Findings That Help You to Confirm Your Definitive Diagnosis? 50.14 How Would You Manage This Patient? 50.15 Follow-up and Prognosis 50.16 Oral Manifestations of Anemia 50.16.1 Specific Oral Manifestations Suggested Reading XIV: Granulomatous Disorders 51: Generalized Swelling of the Lip: Orofacial Granulomatosis 51.1 Main Complaint 51.2 History of Complaint 51.3 With the Findings from the History, What is Your Differential Diagnosis? 51.4 How Do You Justify Your Differential Diagnosis After History Taking? 51.5 Findings of Examination 51.6 What is Your Clinical Differential Diagnosis? 51.7 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 51.8 How Would You Investigate this Patient? 51.9 What Are the Findings of the Investigations? 51.10 What are the Histopathological Findings? 51.11 Do any other Investigations Need to be Performed in Order to Arrive at the Definitive Diagnosis? 51.12 What is the Definitive Diagnosis and Explain the Findings Which Helped You to Arrive at the Definitive Diagnosis? 51.13 How Would You Manage This Patient? 51.14 Orofacial Granulomatosis (OFG) Suggested Reading 52: Swelling of the Lips and Shortness of Breath: Sarcoidosis 52.1 Main Complaint 52.2 History of Complaint 52.3 Additional Complaints 52.4 With the History Findings, What Is Your Differential Diagnosis? 52.5 How Do You Justify Your Differential Diagnosis After History Taking? 52.6 Findings of Examination 52.7 What Other Relevant Features Would You Look for Based on Your Current Findings? 52.8 What Is Your Clinical/Working Diagnosis? 52.9 How Would You Exclude Other Conditions and Justify Your Clinical/Working Diagnosis? 52.9.1 Orofacial Granulomatosis (OFG)/Crohn’s Disease 52.9.2 Sjogren Syndrome 52.9.3 Sarcoidosis 52.10 How Would You Investigate This Patient? 52.11 How Would You Do a Lip Biopsy for This Patient? 52.12 What Are the Histopathological Features Present in Sarcoidosis? 52.13 How Would You Manage This Patient? 52.14 Sarcoidosis Suggested Reading XV: Neurological Disorders 53: Asymmetry of Face: Bell’s Palsy 53.1 Main Complaint 53.2 Additional Complaints 53.3 With the Findings from the History, What Is Your Differential Diagnosis? 53.4 How Do You Justify Your Differential Diagnosis After History Taking? 53.5 Findings of Examination 53.6 What Other Relevant Features Would You Look for with the Findings You Have So Far? 53.7 What Is Your Clinical Diagnosis? 53.8 How Would You Exclude Other Conditions and Justify the Inclusion of the Disease That You Have Mentioned in the Clinical Diagnosis to Arrive at a Working Diagnosis? 53.9 What Is the Most Likely Diagnosis? 53.10 How Would You Investigate This Patient? 53.11 What Is the Final Diagnosis? 53.12 How Would You Manage This Patient? 53.13 Bell’s Palsy Further Reading 54: Unbearable Pain in the Left Lower Jaw: Trigeminal Neuralgia 54.1 Main Complaint 54.2 History of Complaint 54.3 Additional Complaints 54.4 With the Findings from the History, What Is Your Differential Diagnosis? 54.5 How Do You Justify Your Differential Diagnosis After History Taking? 54.6 Findings of Clinical Examination 54.7 What Is Your Clinical Differential Diagnosis? 54.8 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 54.9 What Is the Most Likely Diagnosis? 54.10 How Would You Investigate This Patient? 54.11 Trigeminal Neuralgia Suggested Reading XVI: Temporomandibular Disorders 55: Pain During Mouth Opening: Temporomandibular Disorders (Myalgia) 55.1 Main Complaint 55.2 History of Complaint 55.3 Additional Complaints 55.4 From the Clinical History, What Is Your Differential Diagnosis? 55.5 How Do You Justify Your Differential Diagnosis After History Taking? 55.6 Findings of Examination 55.7 What Is the Most Likely Diagnosis? 55.8 How Do You Justify the Exclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 55.8.1 Dry Socket 55.8.2 Pericoronitis 55.8.3 Acute Periapical Periodontitis 55.8.4 Cracked Tooth 55.8.5 How Would You Investigate This Patient? 55.8.6 How Would You Manage This Patient? 55.9 Temporomandibular Disorders (TMDs) Suggested Reading 56: Bilateral Pain in Front of The Ear During Mouth Opening: Temporomandibular Disorders (Disc Displacement Disorders) 56.1 Main Complaint 56.2 History of Complaint 56.3 Additional Complaints 56.4 With the Findings from the History, What Is Your Differential Diagnosis? 56.5 Findings of Examination 56.6 What Is the Most Likely Diagnosis? 56.7 How Would You Investigate This Patient? 56.8 How Would You Manage This Patient? 56.9 Temporomandibular Joint Disorder (TMD): Disc Displacement Disorders Suggested Reading XVII: Salivary Gland Disorders 57: Dry Mouth and Dry Eyes: Sjogren Syndrome 57.1 Main Complaint 57.2 History of Complaint 57.3 Past Medical History 57.4 Past Dental History 57.5 Social History 57.6 Findings of Extraoral Examination 57.7 Findings of Intraoral Examination 57.8 What Is Your Provisional Diagnosis for This Patient? Give Reasons for Your Diagnosis? 57.9 What Investigations Need to Be Carried out for This Patient? 57.10 What Are the Histopathological Features of the Labial Salivary Gland Biopsy? 57.11 What Is the Definitive Diagnosis for This Patient? 57.12 What Specific Findings Help You to Arrive at the Diagnosis of SS (Clinical Findings and Investigations)? 57.13 What Is the Management Plan for This Patient? Indicate the Rationale for Selecting a Particular Treatment Option If Many Available 57.14 What Is the Prognosis of a Patient with SS? 57.15 Sjogren Syndrome (SS) Suggested Reading 58: Swelling over the Right Cheek: Pleomorphic Adenoma 58.1 Main Complaint 58.2 History of Complaint 58.3 Additional Information 58.4 With the Findings from the History, What is Your Differential Diagnosis? 58.5 How Do You Justify Your Differential Diagnosis After History Taking? 58.6 Findings of Examination 58.7 What is Your Provisional Clinical Diagnosis? 58.8 What is the Justification for Your Provisional Clinical Diagnosis? 58.9 How Would You Investigate This Patient? 58.10 What is the Most Likely Diagnosis Based on Cytological Findings? 58.11 How Would You Manage This Patient? 58.12 The Specimen was sent for Histopathological Examination. What are the Features That Confirm the Diagnosis? 58.13 What is Your Definitive Diagnosis Based on the Histopathological Findings? 58.14 Pleomorphic Adenoma Suggested Reading 59: Swelling in the Floor of the Mouth: Adenoid Cystic Carcinoma 59.1 Main Complaint 59.2 History of Complaint 59.3 Additional Complaints 59.4 Past Medical/Dental and Social History 59.5 With the Findings from the History, What Is Your Differential Diagnosis? 59.6 How Do You Justify Your Differential Diagnosis After History Taking? 59.7 Findings of Clinical Examination 59.8 What Other Relevant Features Are Evident? 59.9 What Is Your Clinical Differential Diagnosis? 59.10 How Would You Exclude Other Conditions and Justify the Inclusion of the Disease That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 59.11 What Is the Most Likely Diagnosis? 59.11.1 Mucoepidermoid Carcinoma 59.11.2 Adenoid Cystic Carcinoma 59.11.3 Polymorphous Adenocarcinoma 59.12 How Would You Investigate This Patient? 59.13 How Would You Perform FNAB and What Are the Important Considerations? 59.14 What Cytopathological Features Would You Expect to See in This Lesion? 59.15 What Would Be the Best Imaging Modality to Investigate This Lesion? 59.16 How Would You Treat This Patient? 59.17 What Are the Histopathological Features That You Would Expect to See in the Excised Specimen? 59.18 Follow Up and Prognosis 59.19 Adenoid Cystic Carcinoma 59.20 Diagnostic Algorithm Suggested Reading 60: A Painless Swelling on the Left Cheek: Warthin Tumour 60.1 Main Complaint 60.2 History of Complaint 60.3 Past Medical/Dental and Social History 60.4 With the Findings from the History, What Is Your Differential Diagnosis? 60.5 How Do You Justify Your Differential Diagnosis After History Taking? 60.6 Findings of Examination 60.7 What Is Your Clinical Differential Diagnosis? 60.8 How Would You Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Exclude Other Conditions? 60.8.1 Pleomorphic Adenoma 60.8.2 Warthin Tumour 60.9 How Would You Investigate the Patient? 60.10 What Is the Reason to Perform an FNAC Without Performing an Incisional Biopsy? 60.11 The Cytology Report Confirms the Previous Clinical Diagnosis of Warthin Tumour. What Are the Cytological Features? 60.12 What Would Be the Best Imaging Modality to Investigate This Lesion? 60.13 How Would You Treat This Patient? 60.14 What Are the Common Complications with Surgery to the Parotid Gland? 60.15 What Histopathological Features Would You Expect to See in the Excision Specimen? 60.16 Follow-Up and Prognosis 60.17 Warthin Tumour 60.18 Diagnostic Algorithm Suggested Reading 61: Intermittent Pain and Swelling in the Floor of the Mouth: Sialolithiasis 61.1 Main Complaint 61.2 History of Complaint 61.3 Additional Complaints 61.4 With the Findings from the History, What is Your Differential Diagnosis? 61.5 How do You Justify Your Differential Diagnosis after History Taking? 61.6 Findings of Examination 61.7 What is Your Clinical Differential Diagnosis? 61.8 How would You Justify Your Clinical Diagnosis? 61.9 What are the Investigations that should be Carried Out in Logical Sequence? 61.10 What are the Findings of Investigations? 61.11 What is the Definitive Diagnosis? 61.12 How would You Manage This Patient? 61.13 Sialolithiasis 61.14 Differential Diagnosis of Sialolithiasis 61.15 Diagnostic Algorithm for Salivary Calculi Suggested Reading 62: A Lump on the Palate: Mucoepidermoid Carcinoma 62.1 Main Complaint 62.2 History of Complaint 62.3 Past Medical, Dental and Social History 62.4 With the Findings from the History, What Is Your Differential Diagnosis? 62.5 How Do You Justify Your Differential Diagnosis After History Taking? 62.6 Findings of Examination 62.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 62.8 What Is Your Clinical Differential Diagnosis? 62.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases that You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 62.9.1 Mucoepidermoid Carcinoma (MEC) 62.9.2 Adenoid Cystic Carcinoma 62.9.3 Polymorphous Adenocarcinoma 62.9.4 Pleomorphic Adenoma 62.10 What Is the Most Likely Diagnosis? 62.11 How Would You Investigate This Patient? 62.12 How Would You Biopsy the Lesion? What Are the Important Considerations? 62.13 Biopsy Report Confirms the Previous Clinical Diagnosis of Mucoepidermoid Carcinoma. What Are the Histopathological Features that Will Help in the Diagnosis? 62.14 What Would Be the Best Imaging Modality to Investigate This Lesion? 62.15 How Would You Manage This Patient? 62.16 Mucoepidermoid Carcinoma 62.17 Diagnostic Algorithm Suggested Reading XVIII: Orofacial Syndromes 63: Multiple Asymptomatic Cysts in the Jaws: Naevoid Basal Cell Carcinoma Syndrome 63.1 Main Complaint 63.2 History of Complaint 63.3 Additional Complaints 63.4 With the Findings from the History, What Is Your Differential Diagnosis? 63.5 How Do You Justify Your Differential Diagnosis After History Taking? 63.6 Findings of Clinical Examination 63.7 What Other Relevant Features Would You Look for with the Findings You Have So Far? 63.8 What Is Your Clinical Differential Diagnosis? 63.9 How Would You Exclude Other Conditions and Justify the Inclusion of the Diseases That You Have Mentioned in the Differential Diagnosis to Arrive at a Working Diagnosis? 63.9.1 Odontogenic Cyst with Possible Gorlin-Goltz Syndrome (GGS) 63.9.2 Odontogenic Tumours 63.9.3 Pathology of the Maxillary Sinus 63.10 What Is the Most Likely Diagnosis? 63.11 How Would You Investigate This Patient? 63.12 What Findings Would You Expect from the Above Investigations? 63.13 What Are the Histopathological Features of the Biopsy from the Cystic Lesion? 63.14 How Would You Confirm the Diagnosis of GGS? 63.15 What Other Additional Investigations Would You Perform? 63.16 How Would You Manage This Patient? 63.17 Gorlin-Goltz Syndrome (GGS) 63.18 Diagnostic Algorithm Suggested Reading 64: A Hard Lump at the Back of the Lower Jaw: Gardner Syndrome 64.1 Main Complaint 64.2 History of Complaint 64.3 Additional Complaints 64.4 Findings of Clinical Examination 64.5 What Other Relevant Features Would You Look for with the Findings You Have So Far? 64.6 With The Findings From The History And Clinical Examination, What is Your Differential Diagnosis? 64.7 How Do You Justify Your Differential Diagnosis? 64.8 What Is the Most Likely Clinical Diagnosis? 64.9 How Would You Investigate This Patient? 64.10 What Are the Investigation Indings? 64.11 What Is the Importance of Investigating Intestinal Symptoms in a Suspected Patient with GS? 64.12 How Do You Confirm the Diagnosis of GS? 64.13 What Is Your Definitive Diagnosis? 64.14 How Would You Manage This Patient? 64.15 What Histopathological Features Would You Expect to See in the Excised Lesion? 64.16 Gardner Syndrome (GS) 64.17 Management Algorithm of GS Suggested Reading XIX: Forensic Odontology 65: Burning Sensation of the Tongue: Burning Mouth Syndrome 65.1 Main Complaint 65.2 History of Complaint 65.3 Additional Information 65.4 With the Findings from the History, What is Your Differential Diagnosis? 65.5 Findings of Examination 65.6 What is Your Provisional Clinical Diagnosis? 65.7 How Would You Exclude Other Conditions and Justify the Inclusion of the Disease That You Have Mentioned as the Diagnosis? 65.7.1 Oral Mucosal Lesions/Diseases 65.7.2 Oral Candidiasis 65.7.3 Local Trauma 65.7.4 Hyposalivation 65.7.5 Endocrine-Related Disorders 65.7.6 Nutritional Deficiency 65.7.7 Medications 65.8 How Would You Investigate This Patient? 65.9 What is Your Definitive Diagnosis Based on the Clinical and Laboratory Results/Findings? 65.10 How Would You Manage This Patient? 65.11 Burning Mouth Syndrome 65.11.1 Management 65.11.2 Topical 65.11.3 Systemic 65.11.4 Others Suggested Reading 66: Forensic Age Estimation: Forensic Odontology 66.1 Main Complaint 66.2 History of Complaint 66.3 Past Dental and Medical History 66.4 Family History 66.5 Social History 66.6 Examination 66.7 What is the Protocol of Conducting Dental Age Estimation? 66.8 Why is Obtaining Personal Information of a Person Important? 66.9 What is the Type of Radiograph Taken for Dental Age Estimation? 66.10 Radiographic Findings 66.10.1 Mr X 66.10.2 Mr Y 66.10.3 Analysis 66.10.3.1 Mr X 66.10.3.2 Mr Y 66.10.4 Results 66.10.4.1 Mr X 66.10.4.2 Mr Y 66.10.5 Conclusion 66.11 Forensic Age Estimation 66.11.1 Dental Age Estimation of Infants, Children and Adolescents 66.11.1.1 Histological Assessment 66.11.1.2 Atlas of Tooth Development 66.11.1.3 Radiographic Assessment 66.11.1.4 Measuring the Apical Foramen of Developing Teeth 66.11.1.5 Third Molar Development 66.11.2 Dental Age Estimation of Adults 66.11.2.1 Secondary Dentin Formation 66.11.2.2 Attrition 66.11.2.3 Root Transparency 66.11.2.4 Cementum Annulations 66.11.2.5 Aspartic Acid Racemisation 66.11.2.6 DNA Methylation 66.11.3 Conclusion Suggested Reading Index