Clinical Obstetrics: The Fetus and Mother Handbook

Cover Page......Page 1
Title Page......Page 4
ISBN 1405132167......Page 5
Contents......Page 6
Contributors......Page 9
Foreword......Page 15
Preface......Page 16
Preface to the first edition......Page 17
Acknowledgments......Page 18
Abbreviations......Page 19
Part I: Conception and Conceptus Development......Page 30
1: Early conceptus growth and immunobiologic adaptations of pregnancy......Page 32
2: Normal embryonic and fetal development......Page 48
Part II: Pregnancy and the Fetoplacental Unit......Page 62
3: Normal and abnormal placentation......Page 64
4: Fetoplacental perfusion and transfer of nutrients......Page 88
5: Endocrinology of pregnancy and the placenta......Page 97
Part III: Fetal Developmental Biology......Page 112
6: Fetal lung development and amniotic fluid analysis......Page 114
7: Fetal cardiovascular physiology and response to stress conditions......Page 122
8: Immunology of the fetus......Page 143
9: Fetal endocrinology......Page 153
10: Fetal hematology......Page 161
Part IV: Variations in Embryonal and Fetal Growth and Development......Page 170
11: Sporadic and recurrent pregnancy loss......Page 172
12: Ectopic and heterotopic pregnancies......Page 190
13: Multifetal pregnancies: epidemiology, clinical characteristics, and management......Page 206
14: Biology of normal and deviant fetal growth......Page 232
Part V: Fetal Infections and Teratogenesis......Page 244
15: Developmental toxicology, drugs, and fetal teratogenesis......Page 246
16: Drugs, alcohol abuse, and effects in pregnancy......Page 265
17: Teratogenic viruses......Page 277
18: Transplacentally acquired microbial infections in the fetus......Page 291
19: Antibiotics and other antimicrobial agents in pregnancy and during lactation......Page 313
Part VI: Fetal Diseases......Page 322
20: Principles of human genetics: chromosomal and singlegene disorders......Page 324
21: Genetic counseling in prenatal and perinatal medicine......Page 347
22: Basic principles of ultrasound......Page 365
23: Prenatal diagnosis of central nervous system malformations......Page 376
24: Prenatal diagnosis of thoracic and cardiac abnormalities......Page 390
25: Gastrointestinal and genitourinary anomalies......Page 406
26: Fetal skeletal anomalies......Page 430
27: First- and second-trimester prenatal diagnosis......Page 502
28: First- and second-trimester screening for open neural tube defects and Down syndrome......Page 514
Part VII: Methods of Evaluation of Fetal Development and Well-being......Page 534
29: Prenatal diagnosis of deviant fetal growth......Page 536
30: Three- and four-dimensional ultrasound and magnetic resonance imaging in pregnancy......Page 555
31: Doppler ultrasonography and fetal well-being......Page 590
32: Antepartum and intrapartum surveillance of the fetus and the amniotic fluid......Page 615
Part VIII: Fetal Therapy......Page 636
33: The fetus at surgery......Page 638
34: Fetal medical treatment......Page 646
Part IX: Maternal Biological Adaptations to Pregnancy......Page 660
35: Maternal biological, biomechanical, and biochemical changes in pregnancy......Page 662
36: Maternal nutrition......Page 674
Part X: Maternal Diseases Complicating Pregnancy......Page 684
37: Trauma, shock, and critical care obstetrics......Page 686
38: Hypertensive diseases in pregnancy......Page 712
39: Cardiac diseases in pregnancy......Page 729
40: Maternal pulmonary disorders complicating pregnancy......Page 747
41: Diabetes mellitus in pregnancy......Page 769
42: Endocrine disorders in pregnancy......Page 791
43: Gastrointestinal diseases complicating pregnancy......Page 806
44: Liver disease in pregnancy......Page 826
45: Pregnancy complicated by renal disorders......Page 840
46: Neurological disorders in pregnancy......Page 847
47: Thromboembolic disorders of pregnancy......Page 854
48: Coagulation and hematological disorders of pregnancy......Page 878
49: Maternal alloimmunization and fetal hemolytic disease......Page 896
50: Maternal infections, human immunodeficiency virus infection, and sexually transmitted diseases in pregnancy......Page 914
51: Rheumatologic and connective tissue disorders in pregnancy......Page 960
52: Dermatologic disorders during pregnancy......Page 976
53: Cancer and other neoplasms in pregnancy......Page 990
Part XI: Medicosocial Considerations in Pregnancy......Page 1014
54: Pregnancy before age 20 years and after age 35 years......Page 1016
55: Essentials in biostatistics and perinatal epidemiology......Page 1036
56: Sexuality in pregnancy and the postpartum period......Page 1045
57: Psychiatric problems during pregnancy and the puerperium......Page 1051
58: Ethical and legal dimensions of medicine of the pregnant woman and fetus......Page 1068
Part XII: Obstetric and Peripartal Events......Page 1076
59: Bleeding in the third trimester......Page 1078
60: Normal and abnormal labor......Page 1094
61: Operative vaginal delivery......Page 1106
62: Preterm labor......Page 1114
63: Prelabor rupture of the membranes......Page 1159
64: Prolonged pregnancy......Page 1218
65: Anesthesia in the high-risk patient......Page 1227
66: Puerperium and lactation: physiology of the reproductive system......Page 1235
Part XIII: The Newborn Infant......Page 1248
67: Premature birth and neurological complications......Page 1250
68: Common problems of the newborn......Page 1261
Index......Page 1290