Clinical manual of blood and bone marrow transplantation

Content: Title Page 
 Copyright Page
 Contents
 Contributors
 Preface
 Chapter 1 Donor and graft selection strategy
 Introduction
 What are the donor options?
 What are the graft sources?
 Donor options
 HLA matching for donor selection
 HLA matching of UCB
 HLA antibodies
 How is DSA tested?
 Graft composition
 PB graft
 BM graft
 Why is BM graft is preferred in children with hematologic malignancies?
 UCB graft
 Which graft type should I use?
 Non-HLA factors 
 What if more than one HLA-matched donor is available? 
 Summary
 Abbreviations
 Selected reading
 Chapter 2 HLA typing and implications IntroductionHLA nomenclature and tissue typing techniques
 Polymorphism
 Unrelated donor search and tools for donor search and selection
 HLA typing for donor search
 The donor search
 Classical HLA alleles: Impact of mismatching
 Non-classical HLA alleles and matching techniques: Impact on outcomes 
 Summary
 Selected reading
 Chapter 3 Risk-benefit assessment in allogeneic hematopoietic transplant: Factors, scores, and models 
 Introduction
 What are the factors to consider prior to HCT?
 Age
 Performance status
 Socioeconomic status
 Race
 Organ function Models used for risk-benefit measurement Models estimating incidences of NRM
 Models estimating relapse risk
 Models estimating all-cause mortality 
 How to evaluate a patient for fitness for HCT
 Guidelines on pretransplantation data gathering
 Summary and practice points for eligibility for HCT
 Acknowledgments
 Conflict of interest
 Selected reading
 Chapter 4 Donor and recipient pre‐transplant evaluation
 Introduction
 Donor infectious evaluation
 History
 Physical examination
 Laboratory testing
 Management
 Special consideration for potentially unsafe products Donor non-infectious evaluation History
 Physical examination
 Laboratory testing
 Instrumental investigations
 Special consideration for female donors of child‐bearing age group
 Recipient infectious evaluation
 History
 Physical examination
 Laboratory testing
 Management
 Recipient non-infectious evaluation 
 Assessment of disease type and status
 Assessment of functional status and comorbidities
 Assessment of psychosocial, financial, and caregiver issues
 Summary
 Selected reading
 Chapter 5 Autologous and allogeneic progenitor cell mobilization
 Introduction
 Autologous mobilization When to use plerixaforWhat if CD34+ cell mobilization fails?
 Some practical aspects of autologous CD34+ cell mobilization
 Allogeneic CD34+ cell mobilization
 What is the best CD34+ cell mobilization regimen for allogeneic healthy volunteer donors?
 What is the optimal PB CD34+ cell dose for allogeneic hematopoietic cell transplantation?
 High yield points
 Selected reading
 Chapter 6 Hematopoietic stem and progenitor cell collection by apheresis: Techniques and tricks 
 Introduction
 Collection techniques and devices used
 Technical/clinical aspects of HPC (A) collections
 Vascular access