Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy

Front Matter....Pages i-xiii
Front Matter....Pages 1-1
Theoretical, Clinical, and Pharmacokinetic Aspects of Cancer Chemotherapy Administered by Continuous Infusion....Pages 3-12
Pharmocology and Therapeutic Efficacy of Bleomycin Administered By Continuous Infusion....Pages 13-17
Continuous-Infusion Adriamycin....Pages 19-25
5-Fluorouracil Plus Thymidine or Leucovorin by Continuous I.V. Infusion in the Treatment of Advanced Colorectal Carcinoma....Pages 27-42
Epipodophyllotoxin and Cisplatin on Continuous Infusion Schedules....Pages 43-50
Biodegradable Starch Microspheres (Spherex), a Clinically Useful Medical Device for Combined Intra-Arterial Chemotherapeutic Treatment of Primary and Metastatic Cancers of the Liver: The Potential Clinical Value for Spherex in Regionalized Immunotherapy, Hyperthermia and Radiation Protection....Pages 51-66
Selective Therapy of Hepatic Cancers Using Microspheres....Pages 67-69
Preliminary Results of a Randomized Study of Intrahepatic Infusion versus Systemic Infusion of FUDR for Metastatic Colorectal Carcinoma....Pages 73-78
COPBLAM: Infusion Chemotherapy for Large Cell Lymphoma....Pages 79-86
Adriamycin Continuous I.V. Infusion for the Treatment of Childhood Hepatic Malignancies, Toxicity, and Efficacy: A Pilot Study Childrens Cancer Study Group, Los Angeles, California....Pages 87-90
An Uncontrolled Phase II Study of Constant Infusion Vincristine-Adriamycin....Pages 91-94
Low-Dose Ara-C by Continuous Infusion in the Treatment of Acute Non-Lymphocytic Leukemia (ANLL) and Myelodysplastic Syndrome (MDS)....Pages 95-100
The 5-Day Continuous Infusion of Cis-Platinum: An Update on Toxicity Pattern....Pages 101-105
Long Term Appraisal of the Lemon-Foley Method of Chemotherapy of Solid Tumors of the Gastrointestinal Tract....Pages 107-110
Front Matter....Pages 111-111
Theoretical Basis and Clinical Applications of 5-Fluorouracil as a Radiosensitizer....Pages 113-125
Treatment of Hepatic Metastases from Gastrointestinal Primaries with Split Course Radiation Therapy and Concomitant Infusion 5-Fluorouracil....Pages 127-132
Combined Modality Therapy With 5-Fluorouracil, Mitomycin C and Radiation Therapy for Squamous Cell Cancers....Pages 133-147
Treatment of Bladder Carcinoma with Concomitant Infusion Chemotherapy and Irradiation....Pages 149-153
A Urologist’s Viewpoint: Treatment of Invasive Bladder Cancer by the XRT/5FU Protocol....Pages 155-157
Concomitant Radiation Therapy and Doxorubicin by Continuous Infusion in Advanced Malignancies - a Phase I-II Study - Evidence Of Synergistic Effect in Soft Tissue Sarcomas and Hepatomas....Pages 159-176
Front Matter....Pages 111-111
CIS Platin By Continuous Infusion with Concurrent Radiation in Malignant Tumors (A Phase I-II Study)....Pages 177-180
Combination of Radiation with Concomitant Continuous Adriamycin Infusion in a Patient with a Partially Excised Pleomorphic Soft Tissue Sarcoma of the Lower Extremity....Pages 183-188
Treatment of Recurrent Carcinoma of the Paranasal Sinuses Using Concomitant Infusion CIS-Platinum and Radiation Therapy....Pages 189-193
Hepatic Artery Infusion (HAI) For Hepatic Metastases in Combination with Hepatic Resection or Hepatic Radiation....Pages 195-199
Phase II Study of Simultaneous Radiation Therapy Continuous Infusion 5-Fu and Bolus Mitomycin-C....Pages 201-205
Cancer of the Esophagus — Medical University of South Carolina Pilot Study....Pages 207-209
Continuous Infusion VP-16, Bolus Cisplatin, and Simultaneous Radiation Therapy as Salvage Therapy in Small Cell Bronchogenic Carcinoma....Pages 211-216
Concomitant Radiation, Mitomycin C And 5 Flourouracil Infusion in Gastrointestinal Cancer - A Preliminary Report....Pages 217-220
Front Matter....Pages 221-221
Procedures for the Use of Implantable and External Pumps for Continuous Infusion Chemotherapy....Pages 223-228
Central Line Catheter Care: The Nurse and the Patient’s Perspective....Pages 229-231
Potential Complications of Right Atrial Catheterization....Pages 233-237
Long Term Complications of the Indwelling Central Line Catheters....Pages 239-242
Back Matter....Pages 243-248