Clinical Applications of Capillary Electrophoresis: Methods and Protocols

Front Matter ....Pages i-xii
Front Matter ....Pages 1-1
 An Overview of CE in Clinical Analysis  (David S. Hage)....Pages 3-11
Front Matter ....Pages 13-13
 Rapid and Sensitive Determination of Branched-Chain Amino Acids in Human Plasma by Capillary Electrophoresis with Contactless Conductivity Detection for Physiological Studies  (Petr Tůma)....Pages 15-24
 Monitorization of α1-Acid Glycoprotein Deglycosylation Using SU-8 Microchips Electrophoresis with LIF Detection  (María del Mar Barrios-Romero, Agustín G. Crevillén, Angel Puerta, Mercedes de Frutos, José Carlos Diez-Masa)....Pages 25-39
 Glycoform Analysis of Alpha1-Acid Glycoprotein by Capillary Electrophoresis Using Electrophoretic Injection  (Chenhua Zhang, William Clarke, David S. Hage)....Pages 41-56
 On-Line Immunoaffinity Solid-Phase Extraction Capillary Electrophoresis-Mass Spectrometry for the Analysis of Serum Transthyretin  (Roger Pero-Gascon, Laura Pont, Victoria Sanz-Nebot, Fernando Benavente)....Pages 57-76
 Measurement of Neutral and Sialylated IgG n-Glycome at Asn-297 by CE-LIF to Assess Hypogalactosylation in Rheumatoid Arthritis  (Christian Schwedler, Véronique Blanchard)....Pages 77-93
 The Control of Glucose and Lactate Levels in Nutrient Medium After Cell Incubation and in Microdialysates of Human Adipose Tissue by Capillary Electrophoresis with Contactless Conductivity Detection  (Petr Tůma)....Pages 95-108
 Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization  (Morten E. Pedersen, Jesper Østergaard, Henrik Jensen)....Pages 109-123
Front Matter ....Pages 125-125
 A Chiral Generic Strategy for Enantioseparation of Acidic and Basic Drugs Using Short End Injection Capillary Electrophoresis: Application to Design of Experiment  (Hassan Y. Aboul-Enein, Ahmed M. Abdel-Megied)....Pages 127-136
Front Matter ....Pages 137-137
 New Advances for Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Mass Spectrometry (CE-MS)  (Meera Shanmuganathan, Philip Britz-McKibbin)....Pages 139-163
 Capillary Electrophoresis-Mass Spectrometry for Metabolic Profiling of Biomass-Limited Samples  (Wei Zhang, Thomas Hankemeier, Rawi Ramautar)....Pages 165-172
Front Matter ....Pages 173-173
 Device Fabrication and Fluorescent Labeling of Preterm Birth Biomarkers for Microchip Electrophoresis  (Anna V. Nielsen, Adam T. Woolley)....Pages 175-184
 Analysis of Inflammatory Mediators in Newborn Dried Blood Spot Samples by Chip-Based Immunoaffinity Capillary Electrophoresis  (Terry M. Phillips, Edward F. Wellner)....Pages 185-198
 Triplet-Repeat Primed PCR and Capillary Electrophoresis for Characterizing the Fragile X Mental Retardation 1 CGG Repeat Hyperexpansions  (Indhu-Shree Rajan-Babu, Samuel S. Chong)....Pages 199-210
Front Matter ....Pages 211-211
 A Capillary Electrophoresis UV Detection-Based Method for Global Genomic DNA Methylation Assessment in Human Whole Blood  (Angelo Zinellu, Elisabetta Sotgiu, Salvatore Sotgia, Ciriaco Carru)....Pages 213-219
 Capillary Electrophoresis Analysis of Prostate-Specific Antigen (PSA)  (Noemi Farina-Gomez, Diana Navarro-Calderon, Angel Puerta, Monica Gonzalez, José Carlos Diez-Masa, Mercedes de Frutos)....Pages 221-234
 Prostate Protein n-Glycosylation Profiling by Means of DNA Sequencer-Assisted Fluorophore-Assisted Carbohydrate Electrophoresis  (Tijl Vermassen, Nico Callewaert, Sylvie Rottey, Joris R. Delanghe)....Pages 235-250
 Aptamer-Based Microchip Electrophoresis Assays for Amplification Detection of Carcinoembryonic Antigen  (Shulin Zhao)....Pages 251-259
Front Matter ....Pages 261-261
 Highly Sensitive SDS Capillary Gel Electrophoresis with Sample Stacking Requiring Only Nanograms of Adeno-Associated Virus Capsid Proteins  (Chao-Xuan Zhang, Michael M. Meagher)....Pages 263-270
Back Matter ....Pages 271-273