Chronically Evolving Viral Hepatitis

Front Matter....Pages i-xi
Front Matter....Pages 1-1
Immune pathogenesis of hepatitis A....Pages 3-4
Relapsing hepatitis A in Saimiri monkeys experimentally reinfected with a wild type hepatitis A virus (HAV)....Pages 5-10
Immune pathogenesis of hepatitis B....Pages 11-18
T cell recognition of hepatitis B envelope proteins....Pages 19-22
Fine specificity of the human T cell response to hepatitis B virus core antigen....Pages 23-28
HBcAg induced T-cell independent anti-HBc production in chronic HBsAg carriers....Pages 29-35
Divergent anti-HBc reactivities in HB-immune and chronic HBsAg carriers....Pages 36-38
Absence of free core antigen in anti-HBc negative viremic hepatitis B carriers....Pages 39-41
Homing of T-lymphocytes in acute and chronic HBV positive inflammatory liver disease....Pages 42-45
Hepatitis B virus specific transcripts in peripheral blood mononuclear cells....Pages 46-49
Detection of transcriptionally active hepatitis B virus DNA in peripheral mononuclear blood cells after infection during immunosuppressive chemotherapy using the polymerase chain reaction....Pages 50-53
Front Matter....Pages 55-55
The hepatitis B virus X protein transactivation of c-fos and c-myc proto-oncogenes is mediated by multiple transcription factors....Pages 57-61
 Trans -activation by hepatitis B virus X protein is mediated via a tumour promoter pathway....Pages 63-64
Truncated pre-S/S proteins transactivate multiple target sequences....Pages 65-69
Hepatitis C virus and hepatocellular carcinoma....Pages 70-75
Prevalence of antibodies to hepatitis C virus in patients with hepatocellular carcinoma in Austria....Pages 76-80
Front Matter....Pages 81-81
Variants of hepatitis B virus....Pages 83-85
Hepatitis B virus (HBV) genomic variations in chronic hepatitis....Pages 86-89
Replication of a molecularly cloned HBeAg negative hepatitis B virus variant in transfected HepG2 cells....Pages 90-94
Lack of pre-C region mutation in woodchuck hepatitis virus from seroconverted woodchucks....Pages 95-96
Front Matter....Pages 81-81
Clinical significance of the polymerase chain reaction (PCR) assay in chronic HBV carriers....Pages 97-101
Front Matter....Pages 103-103
PreS antigen expression and anti-preS response in hepatitis B virus infections: relationship to serum HBV-DNA, intrahepatic HBcAg, liver damage and specific T-cell response....Pages 105-112
PCR analysis of HBV infected sera: relationship between expression of pre-S antigens and viral replication....Pages 113-115
Detection of HBV DNA by PCR in serum from an HBsAg negative blood donor implicated in cases of post-transfusion hepatitis B....Pages 116-118
HBc and HBe specificity of monoclonal antibodies against complete and truncated HBc proteins from E. coli....Pages 119-121
Measurement of anti-HBc IgM levels using the Amerlite anti-HBc IgM assay....Pages 122-123
Evaluation of a new enhanced luminescence immunoassay for confirming the presence of HBsAg in human serum or plasma....Pages 124-125
Front Matter....Pages 127-127
Functions of hepatitis B surface proteins....Pages 129-132
Deletion and insertion mutants of HBsAg particles....Pages 133-136
Properties of a recombinant yeast-derived hepatitis B surface antigen containing S, preS2 and preSl antigenic domains....Pages 137-141
Diverging policies for vaccination against hepatitis B....Pages 142-146
Immunogenicity and safety of a recombinant hepatitis B vaccine produced in mammalian cells and containing the S and the preS2 sequences....Pages 147-153
Kinetics of anti-HBs after hepatitis B vaccination: a comparison of two recombinant and one plasma-derived vaccines....Pages 154-155
Enhanced luminescent assays for hepatitis markers: Assessment of post vaccine responses....Pages 156-159
Front Matter....Pages 161-161
Comparative molecular biology of flaviviruses and hepatitis C virus....Pages 163-171
Hepatitis C viral RNA in serum of patients with chronic non-A, non-B hepatitis: detection by the polymerase chain reaction using multiple primer sets....Pages 172-178
Detection and characterization of hepatitis C virus sequence in the serum of a patient with chronic HCV infection....Pages 179-183
Sequence analysis of PCR amplified hepatitis C virus cDNA from French non-A, non-B hepatitis patients....Pages 184-185
Antigenicity of synthetic peptides derived from C100 protein of hepatitis C virus....Pages 186-190
Localization of hepatitis C virus antigen(s) by immunohistochemistry on fixed-embedded liver tissue....Pages 191-195
Front Matter....Pages 161-161
Identification of HCV-associated antigen(s) in hepatocytes....Pages 196-198
Front Matter....Pages 199-199
Hepatitis C virus (HCV) and autoimmune liver diseases....Pages 201-204
Antibodies to hepatitis C virus in primary biliary cirrhosis....Pages 205-209
Prevalence of antibodies against hepatitis C virus in primary biliary cirrhosis and autoimmune chronic hepatitis....Pages 210-211
HCV infection and chronic active hepatitis in alcoholics....Pages 212-214
Hepatitis C virus infection in patients with idiopathic hemochromatosis (IH) and porphyria cutanea tarda (PCT)....Pages 215-216
Front Matter....Pages 217-217
Diagnostic reagents for hepatitis C virus....Pages 219-221
Follow-up of patients with hepatitis non-A, non-B: incidence and persistence of anti-HCV depend on route of transmission....Pages 222-226
Confirmation of anti-HCV EIA reactivities by RIBA and neutralization assay among blood donors and patients with chronic liver disease and hepatocellular carcinoma....Pages 227-231
Recombinant immunoblot assay for hepatitis C virus antibody in chronic hepatitis....Pages 232-233
PCR detection of HCV RNA among French non-A, non-B hepatitis patients....Pages 234-237
Front Matter....Pages 239-239
HCV and blood transfusion....Pages 241-243
Evaluation of anti-HCV positive blood donors identified during routine screening....Pages 244-246
Presence of HCV RNA in serum of asymptomatic blood donors involved in post-transfusion hepatitis (PTH)....Pages 247-248
Epidemiology of anti-HCV antibodies in France....Pages 249-252
Assay of antibodies to hepatitis C virus protein C100-3 in blood donors from Northern Germany....Pages 253-255
Front Matter....Pages 257-257
Chronic viral hepatitis in children....Pages 259-262
Long-term outcome of chronic type B hepatitis in childhood....Pages 263-264
Hepatitis in children with thalassemia major....Pages 265-267
Hepatitis in pre-school children: prevalent role of cytomegalovirus....Pages 268-272
Front Matter....Pages 257-257
Repeated course of interferon treatment in chronic hepatitis B in childhood....Pages 273-276
Effect of prednisone priming followed by alfa-interferon in treatment of children with chronic hepatitis B: an interim analysis of a controlled trial....Pages 277-280
Association between HLA class I antigens and response to interferon therapy in children with chronic HBV hepatitis....Pages 281-283
Front Matter....Pages 285-285
Treatment of chronic viral hepatitis anno 1990....Pages 287-290
Induction of autoantibodies during alpha interferon treatment in chronic hepatitis B....Pages 291-293
One course versus two courses of recombinant alpha interferon in chronic C hepatitis....Pages 294-298
Interferon therapy of cryptogenic chronic active liver disease and its relationship to anti-HCV....Pages 299-303
Interferon alpha 2-b therapy of HCV and NonBNonC chronic hepatitis....Pages 304-305
Long-term effects of recombinant leukocyte alpha interferon in the treatment of chronic delta hepatitis....Pages 306-307
Front Matter....Pages 309-309
Liver transplantation and hepatitis viruses....Pages 311-316
Front Matter....Pages 317-317
Prevalence of antibody to hepatitis C virus in acute non-A, non-B hepatitis in patients from different epidemiological categories....Pages 319-320
Prevalence of anti-HCV antibodies in patients with acute nonA-nonB viral hepatitis....Pages 321-322
Antibody to hepatitis C virus in acute, self-limited, type B hepatitis....Pages 323-324
HCV infection in HBsAg positive chronic liver disease....Pages 325-326
Prevalence of antibody to hepatitis C virus in chronic HBsAg carriers....Pages 327-328
HBV and HCV infection in i.v. drug addicts; coinfection with HIV....Pages 329-332
HCV and HIV infection among intravenous drug abusers in Eastern Sicily....Pages 333-334
Anti-hepatitis C antibody prevalence among intravenous drug addicts in the Catanzaro area....Pages 335-336
Hepatitis C virus (HCV) infection in the Piacenza dialysis center....Pages 337-338
Prevalence of hepatitis C virus (HCV) antibodies in haemodialysis patients....Pages 339-342
Front Matter....Pages 317-317
Preliminary investigation on intrafamilial spread of hepatitis C virus (HCV)....Pages 343-344
Involved factors in the intrafamilial spread of hepatitis C virus....Pages 345-346
Prevalence of anti-HCV in two Tanzanian villages....Pages 347-348
Back Matter....Pages 349-351