Chronic Renal Disease: Causes, Complications, and Treatment

Front Matter....Pages i-xvi
Front Matter....Pages 1-1
A Personal Perspective on the State of the Art in Research in Glomerulonephritis....Pages 5-7
Biosynthesis and Immunochemical Localization of Glomerular Components....Pages 9-14
The Role of Fixed (Native) and Planted Antigens in Glomerular Disease....Pages 15-28
Deposition of Circulating Immune Complexes in Glomeruli....Pages 29-38
Renal Cystic Disease as the Target of Research....Pages 41-46
Morphology of Human Renal Cystic Disease....Pages 47-54
Morphology of Polycystic Kidney Disease in Man and Experimental Models....Pages 55-68
Ordered and Disordered Growth of Renal Cells....Pages 69-78
Movements of Salts and Water into Cysts in Polycystic Kidney Disease....Pages 79-87
Movement of Organic Molecules into Cysts....Pages 89-93
Kinetics of Cyst Development in Cystic Renal Disease....Pages 95-103
Early Polycystic Kidney Disease....Pages 105-112
Front Matter....Pages 113-113
An Overview of Recent Advances in Mineral Metabolism....Pages 117-125
The Pathology of the Uremic Bone Lesion....Pages 127-138
Vitamin D Metabolism in Chronic Renal Disease....Pages 139-153
Metabolism of Parathyroid Hormone and Interpretation of Radioimmunoassays for PTH....Pages 155-163
Collagen Metabolism in Uremia....Pages 165-172
Neurologic Complications of Renal Failure....Pages 175-184
Dialysis Encephalopathy....Pages 185-200
Uremic Neuropathy....Pages 201-216
Front Matter....Pages 113-113
Cardiovascular Complications in End-Stage Renal Disease Patients....Pages 219-223
Renal Function, Sodium, Volume, and Arterial Pressure Relationships....Pages 225-238
Abnormal Carbohydrate and Lipoprotein Metabolism in Uremia....Pages 239-253
The Role of Blood Pressure Regulation in Uremia....Pages 255-257
The Role of Manipulating Lipids in Uremia....Pages 259-268
Coronary Artery Disease in Diabetic Patients with End-Stage Renal Disease....Pages 269-275
Indicators for Cardiovascular Catastrophe in Diabetic Patients with Renal Failure....Pages 277-283
Front Matter....Pages 285-285
The Child with Renal Failure....Pages 287-290
Prevention of Renal Damage by Early Recognition of Urinary Tract Infections in Childhood....Pages 291-299
Nutritional Requirements for Growth in Children with Renal Insufficiency....Pages 301-308
Protein Utilization in Chronic Renal Insufficiency in Children....Pages 309-320
Renal Osteodystrophy in Children....Pages 321-331
Renal Transplantation in Children Aged 1–5 Years....Pages 333-342
Experience with End-Stage Renal Disease Treatment of Young Children....Pages 343-345
The European Experience with Treatment of End-Stage Renal Disease in Young Children....Pages 347-354
Prognosis of Renal Disease in Infancy....Pages 355-360
Front Matter....Pages 361-361
Drug-Induced Nephrotoxicity....Pages 365-380
Antibiotic Management of Urinary Tract Infection in the Chronic Renal Failure Patient....Pages 381-387
Contrast Media Acute Renal Failure....Pages 389-395
Effect of Renal Disease on Pharmacokinetics and Bioavailability....Pages 397-406
Front Matter....Pages 361-361
Pathogenesis of Aminoglycoside Nephrotoxicity....Pages 407-416
Acute Problems during Hemodialysis....Pages 417-426
The Role of Net Na and H 2 O Flux in the Morbidity of Hemodialysis and Hemofiltration....Pages 429-437
The Role of Small-Molecule Removal in the Control of Treatment Morbidity with Hemodialysis and Hemofiltration....Pages 439-445
The Role of Membrane Biocompatibility on the Clinical Effects of Hemodialysis Therapy....Pages 447-451
Comparative Physiology of Acetate and Bicarbonate Alkalinization....Pages 453-461
The State of the Art....Pages 465-466
Use of Total Lymphoid Irradiation in Organ Transplantation....Pages 467-475
Total Lymphoid Irradiation for Immunosuppression....Pages 477-495
Cyclosporin A as an Immunosuppressive Agent in Transplantation....Pages 497-505
The Pretreatment Principle in Renal Transplantation as Illustrated by Thoracic Duct Drainage....Pages 507-515
Thoracic Duct Drainage....Pages 517-522
Current Status of Induction of Specific Unresponsiveness to Organ Allografts....Pages 523-527
Immunogenetics of HLA....Pages 529-535
Some Questions of a Clinical Nephrologist Concerning Nutritional Therapy and Patients with Chronic Renal Failure....Pages 539-543
The Loss of Renal Enzymes....Pages 545-557
Can Low-Protein Diet Retard the Progression of Chronic Renal Failure?....Pages 559-565
Evaluation of Amino Acid Requirements in Uremia by Determination of Intracellular Free-Amino-Acid Concentrations in Muscle....Pages 567-571
Nutritional Management of Chronic Renal Failure for Two Purposes: Postponing Onset and Reducing Frequency of Dialysis....Pages 573-585
A Progressive Encephalopathy in Children with Renal Failure in Infancy....Pages 587-590
Back Matter....Pages 591-607