Chronic Obstructive Pulmonary Disease

Front Matter....Pages i-xvi
Defining Chronic Obstructive Pulmonary Disease....Pages 1-8
Pathology....Pages 9-34
Lung Structure-Function Relationships....Pages 35-45
Epidemiology: A British Perspective....Pages 47-67
Development of Impaired Lung Function: Natural History and Risk Factors....Pages 69-91
Biochemical and Cellular Mechanisms....Pages 93-133
Lung Mechanics....Pages 135-160
Pulmonary Gas Exchange....Pages 161-184
Respiratory Muscles....Pages 185-203
Ventilatory Control and Dyspnea....Pages 205-242
Pulmonary Circulation, Cardiac Function and Fluid Balance....Pages 243-291
Sleep....Pages 293-308
Clinical and Laboratory Assessment....Pages 309-349
Imaging....Pages 351-372
Smoking Cessation and Prevention....Pages 373-390
Bronchodilators: Basic Pharmacology....Pages 391-417
Symptomatic Bronchodilator Treatment....Pages 419-445
Corticosteroid Treatment....Pages 447-459
Acute Respiratory Failure....Pages 461-494
Domiciliary Oxygen Therapy....Pages 495-526
Pulmonary Rehabilitation....Pages 527-545
Bullous Lung Disease....Pages 547-559
Lung Transplantation....Pages 561-570
Back Matter....Pages 571-579