Chlamydia pneumoniae and Chronic Diseases: Proceedings of the State-of-the-Art Workshop held at the Robert Koch-Institut Berlin on 19 and 20 March 1999

Front Matter....Pages I-XVI
Introduction....Pages 1-2
Pathogenic mechanisms of chronic Chlamydia infections ....Pages 3-7
Biology, immunology and persistence of Chlamydia pneumoniae : Links to chronic disease....Pages 8-18
Animal models for Chlamydia pneumoniae infection....Pages 19-24
Molecular biology and serodiagnostics of Chlamydia pneumoniae — potential way to a vaccine....Pages 25-31
Direct detection of Chlamydia pneumoniae in atherosclerotic plaques....Pages 33-41
Detection of Chlamydia pneumoniae DNA in white blood cells....Pages 42-47
Detection of Chlamydia pneumoniae in clinical specimens by PCR-EIA....Pages 48-51
State of the art in the diagnosis of acute and chronic Chlamydia pneumoniae infection....Pages 52-61
Epidemiological data on respiratory tract infection with Chlamydia pneumoniae and clinical complications....Pages 63-67
Role of C. pneumoniae in severe asthma and COPD: Epidemiology and treatment....Pages 68-72
 Chlamydia pneumoniae in atherosclerosis....Pages 73-83
Prevalence of Chlamydia pneumoniae in human coronary plaques with acute coronary syndrome....Pages 84-90
Chlamydial lipopolysaccharide and atherosclerosis....Pages 91-96
Clinical trial designs to study antibiotic intervention in atherosclerosis....Pages 97-102
Why antibiotics against Chlamydia pneumoniae for treatment of atherosclerotic disease could fail....Pages 103-107
Atherosclerosis: Why the search for a causative infectious agent is not warranted....Pages 108-111
Chlamydia infections and arthritis....Pages 112-120
 Chlamydia pneumoniae , APOE genotype, and Alzheimer’s disease....Pages 121-136
Association of Chlamydia pneumoniae with Multiple Sclerosis: Protocol for detection of C. pneumoniae in the CSF and summary of preliminary results....Pages 137-152
Trends and variations of chronic diseases in populations — Can infectious agents help to solve the puzzles?....Pages 153-162
The epidemiology of Chlamydia pneumoniae versus the epidemiology of potential Chlamydial diseases (Atherosclerosis, Multiple Sclerosis, M. Alzheimer)....Pages 163-170
The high male mortality of coronary heart diseases can be explained as a result of chronic infection....Pages 171-177
The Spandauer Gesundheitstest — Retrospective cohort study on Chlamydia pneumoniae infections and cardiovascular disease — A study concept....Pages 178-183
Public health impact of atherosclerosis and Chlamydia pneumoniae infections — What do we know and what to expect from future research....Pages 184-192
Final Discussion: Pro and Contra the Role of Chlamydia pneumoniae in Chronic Diseases....Pages 193-203