Chemoselective and bioorthogonal ligation reactions : concepts and applications

Content: Contents to Volume 1 List of Contributors xi Preface xvii Part I Chemistries 1 1 A Brief Introduction to Traditional Bioconjugate Chemisrty 3W. Russ Algar 2 (3+2)-Doplar Cycloadditions in Bioconjugation 37Jason E. Hein 3 Diels-Adler and Inverse Diels-Adler Reactions 67Roberto J. Brea and Neal K. Devaraj 4 The Straudinger Ligation 97Olaia Nieto-Garcia, Marcie B. Jaffee, Michaela Muhlberg, and Christian P.R. Hackenberger 5 Thiol-Ene Chemistry 117Neil B. Cramer and Christopher N. Bowman 6 Ligand-Directed Tosyl and Acyl Imidazole Chemisrty 147Kazuya Matsuo and Itaru Hamachi 7 Bioorthogonal Labeling of Cellular Proteins by Enzymatic and Related Mechanisms 165Scott A. Walper, Kendrick B. Turner, and Igor L. Medintz 8 Metal-Mediated Bioconjugation 231Justin M. Chalker Contents to Volume 2 List of Contributors xiii Preface xix Part II applications 271 9 Protein and Anitbody Labeling 273Angela M. Mariani and Kim E. Sapsford 10 Activity-Based Protein Profiling 305Elaine V. Wolf and Steven H.L. Verhelst 11 Nucleic Acid Labeling, Ligation and Modicfication 335Afah H. El-Sagheer and Tom Brown 12 Chemoselective Reactions for Glycan Labeling 363Janet E. McCombs and Jennifer J. Kholer 13 Chemoselective Attachment of Lipids to Proteins 391Christian F. W. Becker 14 In Vivo Applications of Bioorthogonal Chemistries 417Chelsea G. Gordon and Carolyn R. Bertozzi 15 Immobilization of Biomolecular Probes for Arrays and Assays: Critical Aspects of Biointerfaces 459Stella H. North and Chris Rowe Taitt 16 Chemical Ligations in the Design of Hydrogel Materials 497Scott H. Medina and Joel P. Schneider 17 Nanoparticle Bioconjugates: Materials that Benefit from Chemoselective and Bioorthogonal Ligation Chemistires 543Melissa Massey and W. Russ Algar 18 Applications of Engineered Viral Nanoparticles in Materials and Medicine 631Michael D. Glidden II, John F. Edelbrock, Amy M. Wen, Sourabh Shukla, Yingfang Ma, Roger H. French, Jonathan K. Pokorski, and Nicole F. Steinmetz Index 711