Chemoreception: From Cellular Signaling to Functional Plasticity

Front Matter....Pages i-xviii
Honoring Pierre Dejours : His Contribution to the Study of the Role of the Arterial Chemoreceptors in the Regulation of Breathing in Humans....Pages 1-7
2P Domain K + Channels: Novel Pharmacological Targets for Volatile General Anesthetics....Pages 9-23
Ca 2+ responses to hypoxia are mediated by IP 3 -R on Ca 2+ store depletion....Pages 25-32
Functional Identification of Kvα Subunits Contributing to the O 2 -Sensitive K + Current in Rabbit Carotid Body Chemoreceptor Cells....Pages 33-39
Carotid Body Chemoreceptor Activity in Mice Deficient in Selected Subunits of NADPH Oxidase....Pages 41-46
Glucose Sensing Cells in the Carotid Body....Pages 47-53
Effect of Mitochondrial Inhibitors on Type I Cells....Pages 55-58
Ascorbate in the Carotid Body....Pages 59-64
Studies on Glomus Cell Sensitivity to Hypoxia in Carotid Body Slices....Pages 65-73
An Unusual Cytochrome a 592 with Low PO 2 Affinity correlates with Afferent Discharge in the Carotid Body....Pages 75-83
A Reevaluation of the Mechanisms Involved in the Secretion of Catecholamine Evoked by 2, 4-Dinitro Phenol from Chemoreceptor Cells of the Rabbit Carotid Body....Pages 85-93
Enhancing Effect of Vasopressin on the Hyperglycemic Response to Carotid Body Chemoreceptor Stimulation....Pages 95-107
Immunohistochemical Study of the Carotid Body During Acute Hypoxia....Pages 109-116
Effect of HERG-like Potassium Channel Blocker on the Carotid Body Chemoreception....Pages 117-122
The Effect of Methanandamide on Isolated Type I Cells....Pages 123-127
Doxapram Stimulates Carotid Body with Different Mechanisms from Hypoxic Chemotransduction....Pages 129-134
Neuromuscular Blocking Agents and Carotid Body Oxygen Sensing....Pages 135-140
The Pulmonary Interstitium: an Introductory Review....Pages 141-145
Regulation of K + Currents by CO in Carotid Body type I Cells and Pulmonary Artery Smooth Muscle Cells....Pages 147-154
Ionotropic Receptors in Pulmonary Neuroepithelial Bodies (NEB) and their Possible Role in Modulation of Hypoxia Signalling....Pages 155-161
Mitochondrial Complex II is Essential for Hypoxia-induced ROS Generation and Vasoconstriction in the Pulmonary Vasculature....Pages 163-169
Regulation of the Hypoxia-inducible Transcription Factor HIF-1 by Reactive Oxygen Species in Smooth Muscle Cells....Pages 171-178
0 2 -Sensing Mechanisms in Efferent Neurons to the Rat Carotid Body....Pages 179-185
Amyloid Peptide-Mediated Hypoxic Regulation of Ca 2+ Channels in PC12 Cells....Pages 187-192
Role of ROS and NO in Hypoxia-induced Increase in Tyrosine Hydroxylase-messenger RNA in PC12 cells....Pages 193-199
Oxygen Sensing by Human Recombinant Tandem-P Domain Potassium Channels....Pages 201-208
Oxygen Sensing by Human Recombinant Large Conductance,Calcium-activated Potassium Channels....Pages 209-215
Potential Oxygen Sensing Pathways in the Zebrafish Gill....Pages 217-223
Sensory Neurons of Rat and Mice Dorsal Root Ganglia Respond to Hypoxia with Increased NO Generation....Pages 225-230
Molecular Mechanisms of Oxygen-Induced Regulation of Na + /K + Pump....Pages 231-238
The Paraganglia of the Rat Superior Laryngeal Nerve....Pages 239-246
Dye and Electric Coupling between Carotid Nerve Terminals and Glomus Cells....Pages 247-253
Neurotransmitter Relationships in the Hypoxia-challenged Cat Carotid Body....Pages 255-261
ACH Differentially Modulates Voltage-gated K Channels in Glomus Cells between DBA/2J and A/J Strains of Mice....Pages 263-268
Hypoxic Augmentation of Neuronal Nicotinic Acetylcholine Receptors and Carotid Body Function....Pages 269-275
Cholinergic Actions on Carotid Chemosensory System....Pages 277-283
Nicotinic Acetylcholine Receptor Channels in Cat Chemoreceptor Cells....Pages 285-290
Hypoxia Does Not Uniformly Facilitate the Release of Multiple Transmitters from the Carotid Body....Pages 291-296
Expression and Function of Presynaptic Neurotransmitter Receptors in the Chemoafferent Pathway of the Rat Carotid Body....Pages 297-303
Adenosine-Acetylcholine Interactions at the Rat Carotid Body....Pages 305-311
Diverse Cholinergic Receptors in the Cat Carotid Chemosensory Unit....Pages 313-319
Carotid Chemosensory Neurons in the Petrosal Ganglia are Excited by ACh and ATP....Pages 321-326
The Use of NK-1 Receptor Null Mice to Assess the Significance of Substance P in the Carotid Body Function.....Pages 327-336
Concomitant Effect of Acetylcholine and Dopamine on Carotid Chemosensory Activity in Catecholamine Depleted Cats....Pages 337-343
Contribution of Neural and Endothelial Isoforms of the Nitric Oxide Synthase to the Inhibitory Effects of NO on the Cat Carotid Body....Pages 345-351
Nitric Oxide and Calcium Binding Protein in Hypoxic Rat Carotid Body....Pages 353-358
Carotid Body Nitric Oxide Activity in Spontaneously Diabetic BB Rat....Pages 359-366
Contribution of Dopamine D 2 Receptors for the cAMP Levels at the Carotid Body....Pages 367-373
Chemosensitivity of Medullary Respiratory Neurones....Pages 375-387
Effects of Controller Dynamics on Simulations of Irregular and Periodic Breathing....Pages 389-399
C0 2 /H + Signal Transduction and Central Ventilatory Control....Pages 401-406
Differential Expression of Intracellular Acidosis in Rat Brainstem Regions in Response to Hypercapnic Ventilation....Pages 407-413
Tentative Role of the Na + /H + Exchanger Type 3 in Central Chemosensitivity of Respiration....Pages 415-421
Effect of Losartan Microinjections into the NTS on the Cardiovascular Components of Chemically Evoked Reflexes in a Rabbit Model of Acute Heart Ischemia....Pages 423-431
Effects of Acute Hypoxic Conditions on Extracellular Excitatory Amino Acids and Dopamine in the Striatum of Freely-moving Rats....Pages 433-444
Activity of Dorsal Medullary Respiratory Neurons in Awake Rats....Pages 445-453
Cardiovascular and Respiratory Responses to Heme Oxygenase Inhibition in Conscious Rats....Pages 455-460
Peripheral Chemoreceptor Input to Cardiac Vagal Preganglionic Neurones in the Anaesthetised Rat....Pages 461-466
Hypoxic Remodelling of Ca 2+ Homeostasis in Rat Type I Cortical Astrocytes....Pages 467-472
Effect of CO 2 on Cardiovascular Regulation in Conscious Rats....Pages 473-479
A6 Noradrenergic Cell Group Modulates the Hypoxic Ventilatory Response....Pages 481-487
Ventilatory Chemosensory Drive in Cats, Rats and Guinea-pigs....Pages 489-495
Deletion of Tachykinin NK1 Receptor Gene in Mice does not Alter Respiratory Network Maturation but Alters Respiratory Responses to Hypoxia.....Pages 497-504
Autonomic Ganglion Cells : Likely Source of Acetylcholine in the Rat Carotid Body....Pages 505-515
Effects of Perinatal Hyperoxia on Carotid Body Chemoreceptor Activity in Vitro ....Pages 517-524
Prenatal Hypoxia and Early Postnatal Maturation of the Chemoafferent Pathway....Pages 525-533
pH Sensitivity of Spinal Cord Rhythm in Fetal Mice in Vitro ....Pages 535-539
Time Dependent Regulation of Dopamine D 1 - and D 2 - Receptor Gene Expression in the Carotid Body of Developing Rabbits by Hypoxia....Pages 541-547
Ventilatory Response to CO 2 in New Born Mouse....Pages 549-554
Long-term Effects of Neonatal Cryoanesthesia on Hypoxic Ventilatory Response in Weanling Rats Depend on Neonatal Testosterone....Pages 555-558
Systemic and Cellular Responses to Intermittent Hypoxia: Evidence for Oxidative Stress and Mitochondrial Dysfunction....Pages 559-564
Effects of Hypobaric Hypoxia on the Intercellular Coupling of Glomus Cells....Pages 565-571
Oxygen Sensing by Human Recombinant Large Conductance, Calcium-activated Potassium Channels....Pages 573-581
Altered Expression of Vascular Endothelial Growth Factor and FLK-1 Receptor in Chronically Hypoxic Rat Carotid Body....Pages 583-591
Role of HIF-1 in Physiological Adaptation of the Carotid Body during Chronic Hypoxia....Pages 593-601
Carotid Body HIF-1α, VEGF and NOS Expression during Aging and Hypoxia....Pages 603-610
Rat Carotid Bodies in Systemic Hypoxia....Pages 611-617
Immunohistochemical Study of the Carotid Body just after Arousal from Hibernation....Pages 619-628
Back Matter....Pages 629-633