Cerebral Ischemia and Dementia

Front Matter....Pages I-XV
Front Matter....Pages 1-1
How Does Cerebrovascular Disease Cause Dementia?....Pages 3-6
Front Matter....Pages 7-7
The Epidemiology of Vascular Dementia....Pages 9-15
Epidemiology of Vascular Dementia and Stroke in Akita, Japan....Pages 16-24
Dementia in Stroke Survivors....Pages 25-30
Front Matter....Pages 31-31
The Anatomical Substrate of Ischemic Vascular Dementia....Pages 33-38
Vascular Dementia: The Search for a Correlate....Pages 39-53
Incomplete Infarction Is an Important Component in Cerebrovascular Dementia....Pages 54-59
Front Matter....Pages 61-61
Molecular Biology of Atherothrombotic Brain Infarction and Its Role in Vascular Dementia....Pages 63-68
Cellular Aspects of Atherosclerosis and Approaches to Intervention: A Mechanism to Reduce Stroke and Vascular Dementia Risk....Pages 69-76
Inhibition of Atherogenesis In Vivo and In Vitro....Pages 77-84
Front Matter....Pages 85-85
Alzheimer’s Disease: Role of Energy Metabolism and Treatment of Symptoms....Pages 87-93
Neurochemical Changes in Brains from Patients with Vascular Dementia....Pages 94-102
Subcortical Changes Following Ischaemic and Other Lesions of Cerebral Cortical Structures: Trophic Mechanisms and Neuronal Degeneration....Pages 103-120
Front Matter....Pages 121-121
Selective Vulnerability of the CA1 Sector in the Gerbil After 5 Minutes of Global Ischemia: Relationship to Disturbances in Protein Synthesis and to Motor Hyperactivity....Pages 123-131
Energy Metabolism in Cortex and Hippocampus During Aging, Ischemia, and Dementia....Pages 132-148
Mechanisms of Glial Swelling from Lactacidosis and High K + Levels in the Extracellular Compartment....Pages 149-156
Potential Mechanisms Underlying Protection Against Cerebral Ischemia by Spontaneous Locomotion in Mongolian Gerbils....Pages 157-160
Glutamate: A Role in Both Cerebral Ischaemia and Dementia of the Alzheimer Type....Pages 161-172
Sabeluzole Enhances Spontaneous EEG Activity and SSEP, and Accelerates Their Posthypoxic Recovery in Rat....Pages 173-182
Front Matter....Pages 183-183
Linkage Analysis in Italian Pedigrees with Autosomal Dominant Familial Alzheimer’s Disease....Pages 185-186
Front Matter....Pages 183-183
RBC Aggregation Is Not a Primary Factor for Microvascular Stasis on Temporary Complete Ischemia of the Feline Brain....Pages 187-192
White Blood Cell Behavior in the Cerebral Microcirculation....Pages 193-196
Improved Learning with N -Methyl- D -aspartate Receptor Antagonist After Global Cerebral Ischemia....Pages 197-201
Electrophysiological Markers of the Early Stages of Alzheimer’s Disease....Pages 202-216
Front Matter....Pages 217-217
Neuropsychological Assessment of Demented Patients....Pages 219-224
Multiinfarct and Microinfarct Dementia....Pages 225-233
Acute Aphasia....Pages 234-243
Front Matter....Pages 245-245
Cerebral Hemodynamics in Patients with Periventricular White-Matter Lesions on Brain Imaging....Pages 247-254
The Relation of Stroke to Leukoaraiosis....Pages 255-259
Computed Tomographic Evaluation of the Cervical Carotid Artery....Pages 260-265
Magnetic Resonance Imaging and Spectroscopy: A Unique Approach to Ischemic Cerebrovascular Disease....Pages 266-275
Imaging Techniques and Neuropsychological Testing in Dementia with Severe White Matter Changes....Pages 276-284
Front Matter....Pages 285-285
Cerebral Ischemia Correlates Better with Cognitive Impairments in Mild to Moderate Multi-Infarct Dementia than Infarcted Brain Volume....Pages 287-295
Regional Cerebral Blood Flow in Binswanger’s Disease....Pages 296-302
Front Matter....Pages 303-303
Cognitive Utilization of Cerebral Vasomotor Reserve in Cerebrovascular Disease....Pages 305-309
Tomographic Measurements of Regional Cerebral Blood Flow by SPECT in Vascular Dementia....Pages 310-315
Contribution of HM-PAO-SPECT and 133 Xe-rCBF to the Differential Diagnosis of Dementia as Experienced in Clinical Practice....Pages 316-321
Intracerebral Reserve Assessment with SPECT: Reactivity to Acetazolamide and Cerebral Blood Volume Measurement....Pages 322-326
SPECT Brain Imaging in Chronic Stroke and Dementia: A Comparison of 99m Tc-ECD and 99m Tc-HMPAO....Pages 327-333
CSF α 1 -Antichymotrypsin and Antitrypsin in Multi-Infarct Dementia and Alzheimer’s Disease....Pages 334-337
Front Matter....Pages 339-339
Functional Recovery After Cerebral Ischemia: Studies in the Motor System....Pages 341-346
Detection of Structural and Metabolic Changes of the Brain in Normal Aging and Dementia with Modern Imaging Techniques....Pages 347-359
Subcortical Lesions and Dementia: The Role of Positron Emission Tomography....Pages 360-367
PET Metabolic and Neuropsychological Correlates of Periventricular Lucencies....Pages 368-373
Front Matter....Pages 375-375
Accuracy of the Antemortem Diagnosis and Neuropathological Features of Multi-Infarct Dementia....Pages 377-381
Development and Evaluation of the Maudsley Mentation Scale for Bedside Measurement of Fluctuations in Cognitive Function in Patients with Acute Vascular Lesions: Comparison with the Glasgow Coma Scale....Pages 382-385
Acute Confusional States After Stroke: Occurrence, Determinants, and Neuroendocrine Correlates....Pages 386-394
The Prognosis of Stroke in the Elderly....Pages 395-399
Thalamic Dementia and Pseudodementia....Pages 400-403
Front Matter....Pages 405-405
Positron Emission Tomography in Cerebrovascular Disease: Implications for Therapy?....Pages 407-415
A Clinical Trial of Pentoxifylline in Vascular Dementia....Pages 416-423
Rheological Therapy of Vascular Dementia: A Rational Basis?....Pages 424-431
Monosialoganglioside in Subarachnoid Hemorrhage....Pages 432-434
GM 1 Ganglioside Therapy in Acute Ischemic Stroke....Pages 435-441
Communicating Hydrocephalus — Diagnosis and Management....Pages 442-445
Assessment of CSF Volume in Normal Subjects and Patients with Dementia Due to Normal Pressure Hydrocephalus....Pages 456-461
Back Matter....Pages 463-472