Cellular and Molecular Biology of Myelination

Front Matter....Pages I-XVII
Front Matter....Pages 1-1
The O-2A Progenitor during Development and Remyelination....Pages 3-17
Regulation of Oligodendrocyte Progenitor Development: Antibody-Perturbation Studies....Pages 19-31
Oligodendrocyte Differentiation: Developmental and Functional Subpopulations....Pages 33-45
Long-Term Tissue Cultures of Newborn Rat Optic Nerve Cells : Functional Differentiation of Glia and Appearance of Neuron-Like Cells....Pages 47-58
Distribution of Myelin Protein Gene Products in Actively-Myelinating Oligodendrocytes....Pages 59-79
Immuno-Localization of Sodium Channels in Axon Membrane and Astrocytes and Schwann Cells in vivo and in vitro....Pages 81-97
Front Matter....Pages 99-99
Some Aspects of Mechanisms of Inflammatory Demyelination....Pages 101-113
Tellurium-Induced Demyelination....Pages 115-128
Oligodendrocyte Reaction to Axonal Damage....Pages 129-142
Glial Cell Differentiation in Regeneration and Myelination....Pages 143-154
Aggregating Brain Cell Cultures: A Model to Study Myelination and Demyelination....Pages 155-170
The Transplantation of Glial Cells into Areas of Primary Demyelination....Pages 171-184
Remyelination of a Chemically Induced Demyelinated Lesion in the Spinal Cord of the Adult Shiverer Mouse by Transplanted Oligodendrocytes....Pages 185-198
Front Matter....Pages 199-199
cAMP-Dependent Protein Kinase: Subunit Diversity and Functional Role in Gene Expression....Pages 201-215
Protein Kinase C in Neuronal Cell Growth and Differentiation....Pages 217-230
Oligodendrocyte-Substratum Interaction Signals Cell Polarization and Secretion....Pages 231-246
Protein Kinases A and C are Involved in Oligodendroglial Process Formation....Pages 247-253
Growth Factors in Human Glial Cells in Culture....Pages 255-279
Regulation of Oligodendrocyte Development by Insulin-Like Growth Factors and Cyclic AMP....Pages 281-292
Platelet-Derived Growth Factor and Its Receptors in Central Nervous System Gliogenesis....Pages 293-307
Front Matter....Pages 309-309
Gene Transfer of Rat Mature Oligodendrocytes and O-2A Progenitor Cells with the ß-Galactosidase Gene....Pages 311-316
Immortalization of Oligodendrocyte Precursors from the Optic Nerve of the Rat with a Temperature-Sensitive form of the SV40 T Antigen Using a Retrovirus Vector....Pages 317-327
Expression of Nervous System cDNAs in Glial and Non-Glial Cell Lines....Pages 329-339
Front Matter....Pages 341-341
Myelin and Myelin-Forming Cells in the Brain of Fish — A Cell Culture Approach....Pages 343-359
Myelin Proteolipid Protein: Cladistic Tool to Study Vertebrate Phylogeny....Pages 361-372
Phylogenetic Aspects of Myelin Structure....Pages 373-387
Front Matter....Pages 389-389
Composition and Metabolism of Myelin Cerebrosides and Gangliosides....Pages 391-404
Receptor Activity and Signal Transduction in Myelin....Pages 405-416
Myelin Oligodendrocyte Glycoprotein — a Model Target Antigen for Antibody Mediated Demyelination....Pages 417-431
Role of an Endogenous Mannosyl-Lectin in Myelination and Stabilization of Myelin Structure....Pages 433-450
Myelin Gene Regulation in the Peripheral Nervous System....Pages 451-461
GTP-Binding Proteins associated with CNS Myelin....Pages 463-471
Front Matter....Pages 473-473
Molecular Approaches to the Study of the Regulation of Myelin Synthesis....Pages 475-487
From Myelin Basic Protein to Myelin Deficient Mice....Pages 489-503
Proteolipid protein: From the primary structure to the gene....Pages 505-516
Developmental Expression of the Myelin Proteolipid Protein Gene....Pages 517-532
The Myelination Cascade....Pages 533-541
Back Matter....Pages 543-569