Cellular and Molecular Basis of Synaptic Transmission

Front Matter....Pages I-XV
The Cellular Basis of Synaptic Transmission: An Overview....Pages 1-23
Specializations of Subsynaptic Cytoplasms. Comparison of Axospinous Synapses and Neuromuscular Junctions....Pages 25-50
New Evidence Supporting the Vesicle Hypothesis for Quantal Secretion at the Neuromuscular Junction....Pages 51-72
Poststimulation Increase of Synaptic Vesicle Number in the Preganglionic Nerve Terminals of the Cat Sympathetic Ganglion In Vivo ....Pages 73-82
Synaptic Vesicle Classes in Torpedo and Skate Electric Organ and Muscle....Pages 83-95
Effect of Nerve Stimulation, K + Saline and Hypertonic Saline on Classes of Quanta, Quantal Content and Synaptic Vesicle Size Distribution of Torpedo Electric Organ....Pages 97-120
Fine Structural Correlates of Calcium Dynamics in the Presynaptic Terminal....Pages 121-135
Differential Release of Transmitters and Neuropeptides Co-Stored in Central and Peripheral Neurons....Pages 137-151
The Detection, Isolation and Properties of Sub-Populations of Mammalian Brain Synaptosomes of Defined Neurotransmitter Type....Pages 153-169
Excitatory Amino Acids; Physiology, Anatomy and Biochemistry....Pages 171-183
Synaptosomal Bioenergetics and the Mechanism of Amino Acid Transmitter Release....Pages 185-198
Heterologous Carriers Located on Rat CNS Nerve Endings and their Possible Role in the Modulation of Transmitter Release....Pages 199-213
Spontaneous Release of Acetylcholine from Torpedo Electromotor Neurons....Pages 215-227
The Mechanism of Acetylcholine Release: Its Essential Component, the Mediatophore....Pages 229-239
Potassium Channels in Rat Brain Synaptosomes: Pharmacology and Toxicology....Pages 241-261
Calcium Channels and Na + /Ca 2+ Exchange in Synaptosomes....Pages 263-284
Properties of Presynaptic Voltage-Sensitive Calcium Channels in Rat Synaptosomes....Pages 285-291
Mechanisms of Failure of Synaptic Transmission During Anoxia....Pages 293-304
Adrenergic and Cholinergic Vesicles: Are there Common Antigens and Common Properties?....Pages 305-314
Structure and Function of Synaptic Vesicles:New Aspects....Pages 315-324
Complexity and Regulation in the Acetylcholine Storage System of Synaptic Vesicles....Pages 325-335
Synaptic Vesicle Proteins....Pages 337-350
Synaptophysin: A Major Cell Type-Specific Vesicle Protein of Neuroendocrine Cells....Pages 351-356
The New Paradigm: Sympathetic Neurotransmission by Lateral Interaction Between Single Mixed Quanta Acting in Two Different Biophases....Pages 357-375
Sympatho-Adrenal Co-Storage, Release and Synthesis of Enkephalins and Catecholamines Induced by Acute CNS Ischemia in Pig....Pages 377-393
Extracellular Metabolism of ATP at the Cholinergic Electromotor Synapse: Characterization and Location of Ectonucleotidases....Pages 395-410
The Application of Immunoaffinity Techniques to the Study of Cholinergic Neurobiology....Pages 411-424
Transmitter/Modulator Induced Events Related to Excitation-Contraction Coupling in Skeletal Muscle of Vertebrates. Action of ATP.....Pages 425-441
Identity and Functional Role of Neuropeptides in Torpedo Electric Organ....Pages 443-452
Mechanisms Regulating the Expression and Function of Acetylcholine Receptor....Pages 453-461
Antibodies as Probes of the Structure of the Nicotinic Acetylcholine Receptor....Pages 463-473
Brain α-Neurotoxin-Binding Proteins and Nicotinic Acetylcholine Receptors....Pages 475-492
Human Neuroblastoma Cells: An in Vitro Model for the Study of Mammalian Neuronal Nicotinic Receptors....Pages 493-506
Molecular Biology Approaches to the Function and Development of CNS Synapses.....Pages 507-524
Recent Studies on Opioid Receptors....Pages 525-539
Back Matter....Pages 541-550